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Drugs target to EGLN3
| Drug name | Drug type | Disease/phenotype | Mechanism of action(MoA) | Phase | Status | Source |
|---|---|---|---|---|---|---|
| VADADUSTAT | Small molecule | chronic kidney disease | Egl nine homolog 3 inhibitor | 3.0 | Suspended | ClinicalTrials |
| ROXADUSTAT | Small molecule | chronic kidney disease | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 1.0 | Terminated | ClinicalTrials |
| ROXADUSTAT | Small molecule | myelodysplastic syndrome | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | Active, not recruiting | ClinicalTrials |
| ROXADUSTAT | Small molecule | ST Elevation Myocardial Infarction | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Recruiting | ClinicalTrials |
| ROXADUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | - | ATC |
| VADADUSTAT | Small molecule | liver disease | Egl nine homolog 3 inhibitor | 1.0 | Completed | ClinicalTrials |
| VADADUSTAT | Small molecule | chronic kidney disease | Egl nine homolog 3 inhibitor | 2.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 4.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Terminated | ClinicalTrials |
| ROXADUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | Recruiting | ClinicalTrials |
| VADADUSTAT | Small molecule | anemia (phenotype) | Egl nine homolog 3 inhibitor | 3.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | chronic kidney disease | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 4.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | peripheral vascular disease | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | injury | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 1.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 4.0 | - | ATC |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 1.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | chronic kidney disease | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 3.0 | Completed | ClinicalTrials |
| ROXADUSTAT | Small molecule | kidney disease | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 1.0 | Completed | ClinicalTrials |
| DAPRODUSTAT | Small molecule | anemia (phenotype) | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Completed | ClinicalTrials |
| VADADUSTAT | Small molecule | anemia (phenotype) | Egl nine homolog 3 inhibitor | 3.0 | - | ATC |
| ROXADUSTAT | Small molecule | myelodysplastic syndrome | Hypoxia-inducible factor prolyl hydroxylase inhibitor | 2.0 | Active, not recruiting | ClinicalTrials |