Drugs target to HSP90AB1

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
RETASPIMYCIN HYDROCHLORIDESmall moleculenoneHeat shock protein HSP90 inhibitor3['Terminated', 'Terminated', 'Completed', 'Withdrawn', 'Completed', 'Withdrawn', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
RETASPIMYCINSmall moleculenoneHeat shock protein HSP90 inhibitor3['Withdrawn', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Withdrawn', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ALVESPIMYCINSmall moleculenoneHeat shock protein HSP90 inhibitor2['Terminated', 'Terminated', 'Terminated', 'Completed', 'Unknown status']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
BIIB021Small moleculenoneHeat shock protein HSP90 inhibitor2['Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
GANETESPIBSmall moleculenoneHeat shock protein HSP90 inhibitor3['Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Recruiting', 'Completed', 'Terminated', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
TANESPIMYCINSmall moleculenoneHeat shock protein HSP90 inhibitor3['Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Terminated', 'Completed', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
LUMINESPIBSmall moleculenoneHeat shock protein HSP90 inhibitor2['Completed', 'Unknown status', 'Withdrawn', 'Terminated', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Terminated', 'Completed', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
SNX 5422Small moleculenoneHeat shock protein HSP90 inhibitor2['Completed', 'Completed', 'Terminated', 'Completed', 'Completed', 'Terminated']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ONALESPIBSmall moleculenoneHeat shock protein HSP90 inhibitor1['Completed', 'Terminated', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Active, not recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
CD24FCUnknownnoneHeat shock protein HSP90 inhibitor3['Completed', 'Terminated', 'Withdrawn']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']