Drugs target to XPO1

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
SELINEXORSmall moleculeacute myeloid leukemiaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculebreast cancerExportin-1 inhibitor2.0CompletedClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor3.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculeacute myeloid leukemiaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculemyelodysplastic syndromeExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeovarian carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeacute myeloid leukemiaExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculeneoplasm of mature B-cellsExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculediffuse large B-cell lymphomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculehepatocellular carcinomaExportin-1 inhibitor1.0TerminatedClinicalTrials
SELINEXORSmall moleculeCOVID-19Exportin-1 inhibitor2.0CompletedClinicalTrials
SELINEXORSmall moleculebreast cancerExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculededifferentiated liposarcomaExportin-1 inhibitor2.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculesquamous cell carcinomaExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculemetastatic melanomaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculeacute lymphoblastic leukemiaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculemixed phenotype acute leukemiaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculemyelodysplastic syndromeExportin-1 inhibitor2.0CompletedClinicalTrials
SELINEXORSmall moleculeThymomaExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculemetastatic melanomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeneoplasm of mature B-cellsExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculeneoplasmExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculeendometrial cancerExportin-1 inhibitor3.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculediabetic footExportin-1 inhibitor1.0WithdrawnClinicalTrials
SELINEXORSmall moleculeglioblastoma multiformeExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculealveolar soft part sarcomaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculeEpstein-Barr virus-positive diffuse large B-cell lymphoma of the elderlyExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculerectum cancerExportin-1 inhibitor1.0Unknown statusClinicalTrials
SELINEXORSmall moleculeacute lymphoblastic leukemiaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor2.0WithdrawnClinicalTrials
SELINEXORSmall moleculeunspecified peripheral T-cell lymphomaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculeurothelial carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculediffuse large B-cell lymphomaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculeacute myeloid leukemiaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculelymphomaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculecolorectal neoplasmExportin-1 inhibitor1.0TerminatedClinicalTrials
SELINEXORSmall moleculecutaneous melanomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeCOVID-19Exportin-1 inhibitor2.0WithdrawnClinicalTrials
SELINEXORSmall moleculeAL amyloidosisExportin-1 inhibitor0.5WithdrawnClinicalTrials
SELINEXORSmall moleculeacute myeloid leukemiaExportin-1 inhibitor2.0CompletedClinicalTrials
SELINEXORSmall moleculediffuse large B-cell lymphomaExportin-1 inhibitor1.0Not yet recruitingClinicalTrials
SELINEXORSmall moleculemyelodysplastic syndromeExportin-1 inhibitor2.0WithdrawnClinicalTrials
SELINEXORSmall moleculeRichter syndromeExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculeFallopian Tube CarcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeendometrial cancerExportin-1 inhibitor3.0RecruitingClinicalTrials
SELINEXORSmall moleculeglioblastoma multiformeExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculemetastatic colorectal cancerExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculeprostate cancerExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculebreast carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculediffuse large B-cell lymphomaExportin-1 inhibitor4.0-DailyMed
SELINEXORSmall moleculeprimary peritoneal carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor2.0Not yet recruitingClinicalTrials
SELINEXORSmall moleculemyelofibrosisExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculegliosarcomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculenon-small cell lung carcinomaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculeacute leukemia of ambiguous lineageExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor1.0WithdrawnClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculechronic myelogenous leukemiaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculesquamous cell lung carcinomaExportin-1 inhibitor1.0WithdrawnClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor2.0CompletedClinicalTrials
SELINEXORSmall moleculemelanomaExportin-1 inhibitor1.0Active, not recruitingClinicalTrials
SELINEXORSmall moleculeThymomaExportin-1 inhibitor2.0Unknown statusClinicalTrials
SELINEXORSmall moleculecancerExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculesmall cell lung carcinomaExportin-1 inhibitor2.0TerminatedClinicalTrials
SELINEXORSmall moleculediffuse large B-cell lymphomaExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculesarcomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculeneoplasmExportin-1 inhibitor4.0-ATC
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor1.0Not yet recruitingClinicalTrials
SELINEXORSmall moleculeneoplasm of mature B-cellsExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculemyelofibrosisExportin-1 inhibitor2.0RecruitingClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor3.0RecruitingClinicalTrials
SELINEXORSmall moleculeneoplasm of mature B-cellsExportin-1 inhibitor1.0SuspendedClinicalTrials
SELINEXORSmall moleculerenal cell carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculetherapy related acute myeloid leukemia and myelodysplastic syndromeExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculemultiple myelomaExportin-1 inhibitor4.0-FDA,DailyMed
SELINEXORSmall moleculelymphoid neoplasmExportin-1 inhibitor1.0CompletedClinicalTrials
SELINEXORSmall moleculecancerExportin-1 inhibitor1.0WithdrawnClinicalTrials
SELINEXORSmall moleculenon-small cell lung carcinomaExportin-1 inhibitor1.0RecruitingClinicalTrials
SELINEXORSmall moleculesoft tissue sarcomaExportin-1 inhibitor1.0CompletedClinicalTrials