Drugs target to NDUFS1

Drug name Drug type Disease/phenotype Mechanism of action(MoA) Phase Status Source
METFORMINSmall moleculenoneMitochondrial complex I (NADH dehydrogenase) inhibitor4['Completed', 'Completed', 'Enrolling by invitation', 'Completed', 'Completed', 'Active, not recruiting', 'Active, not recruiting', 'Completed', 'Recruiting', 'Completed', 'Withdrawn', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Recruiting', 'Completed', 'Suspended', 'Terminated', 'Terminated', 'Unknown status', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Active, not recruiting', 'Completed', '-', 'Recruiting', 'Not yet recruiting', 'Terminated', 'Completed', 'Completed', 'Recruiting', 'Recruiting', 'Recruiting', 'Unknown status', 'Completed', 'Not yet recruiting', 'Completed', 'Suspended', 'Unknown status', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Withdrawn', 'Active, not recruiting', 'Recruiting', 'Enrolling by invitation', 'Recruiting', 'Completed', 'Active, not 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'Completed', 'Completed', '-', 'Completed', 'Terminated', 'Recruiting', 'Active, not recruiting', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Unknown status', 'Active, not recruiting', 'Completed', 'Not yet recruiting', 'Recruiting', 'Unknown status', 'Active, not recruiting', 'Completed', 'Unknown status', 'Completed', 'Unknown status', 'Completed', 'Completed', 'Completed', 'Completed', 'Completed', 'Unknown status', 'Terminated', 'Completed', 'Completed', 'Completed', 'Terminated', 'Not yet recruiting', 'Recruiting', 'Completed', 'Completed', 'Recruiting', 'Completed', 'Recruiting', 'Recruiting', 'Completed', 'Terminated', 'Suspended', 'Terminated', 'Completed', 'Not yet recruiting', 'Completed', 'Completed', 'Terminated', 'Unknown status', 'Not yet recruiting', 'Recruiting', 'Completed', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Unknown status', 'Withdrawn', 'Recruiting', 'Unknown status', 'Completed', 'Recruiting', 'Recruiting', 'Active, not 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'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
METFORMIN HYDROCHLORIDESmall moleculenoneMitochondrial complex I (NADH dehydrogenase) inhibitor4['Unknown status', 'Recruiting', 'Completed', 'Recruiting', 'Active, not recruiting', 'Recruiting', 'Completed', 'Unknown status', 'Recruiting', 'Active, not recruiting', 'Terminated', 'Not yet recruiting', 'Completed', 'Suspended', 'Not yet recruiting', 'Recruiting', 'Recruiting', 'Withdrawn', 'Completed', 'Active, not recruiting', 'Completed', 'Completed', 'Completed', 'Recruiting', 'Withdrawn', 'Recruiting', 'Active, not recruiting', 'Withdrawn', 'Not yet recruiting', 'Completed', 'Withdrawn', 'Not yet recruiting', 'Completed', 'Withdrawn', 'Completed', 'Recruiting', 'Completed', '-', 'Unknown status', 'Terminated', 'Suspended', 'Completed', 'Recruiting', 'Recruiting', 'Suspended', 'Suspended', 'Suspended', 'Completed', 'Withdrawn', '-', 'Recruiting', 'Completed', 'Completed', 'Completed', 'Not yet recruiting', 'Suspended', 'Unknown status', 'Active, not recruiting', 'Suspended', 'Active, not recruiting', 'Completed', 'Suspended', 'Not yet recruiting', 'Completed', 'Recruiting', 'Completed', 'Completed', 'Withdrawn', 'Completed', 'Suspended', 'Unknown status', 'Suspended', 'Suspended', 'Not yet recruiting', 'Withdrawn', 'Active, not recruiting']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'DailyMed,FDA', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']
ME-344Small moleculenoneMitochondrial complex I (NADH dehydrogenase) inhibitor1['Completed', 'Terminated', 'Completed']['ClinicalTrials', 'ClinicalTrials', 'ClinicalTrials']