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| Ensembl ID | ENSG00000278637 | Gene ID | 8359 | Accession | 4781 |
| Gene Symbol | H4C1 | Alias | H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4FA;H4-16;H4C11;H4C12;H4C13;H4C14;H4C15;H4C16;HIST1H4A | Full Name | H4 clustered histone 1 |
| Position | 6 : 26021649 - 26022050 | Length | 402 bases | Strand | Plus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015] | ||||
ENSG00000278637 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000278637 | 3.24 | 8.02e-23 | BRCA | |
| ENSG00000278637 | 3.31 | 2.82e-15 | UCEC | |
| ENSG00000278637 | 3.78 | 1.31e-13 | LUAD |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000278637 | tumors | 10344733 | |
| ENSG00000278637 | tumour | 10376979 | |
| ENSG00000278637 | breast cancer | 11682064 | |
| ENSG00000278637 | Skin tumors | 11782361 | |
| ENSG00000278637 | tumor | 12385581 | |
| ENSG00000278637 | tumor | 12579268 | |
| ENSG00000278637 | gastric cancer | 12677198 | |
| ENSG00000278637 | colorectal cancers | 12724227 | |
| ENSG00000278637 | cancer | 12865631 | |
| ENSG00000278637 | Tumor | 12891711 | |
| ENSG00000278637 | tumor | 12939461 | |
| ENSG00000278637 | colon cancer | 12975486 | |
| ENSG00000278637 | tumours | 14614037 | |
| ENSG00000278637 | cancer | 15095300 | |
| ENSG00000278637 | cancer | 15765097 | |
| ENSG00000278637 | cancer | 16131487 | |
| ENSG00000278637 | tumors | 16205112 | |
| ENSG00000278637 | tumor | 16254189 | |
| ENSG00000278637 | tumors | 16270534 | |
| ENSG00000278637 | breast cancer | 16322686 | |
| ENSG00000278637 | tumours | 16404435 | |
| ENSG00000278637 | tumor | 1644858 | |
| ENSG00000278637 | tumor | 16488987 | |
| ENSG00000278637 | tumor | 16497704 | |
| ENSG00000278637 | tumor | 16699174 | |
| ENSG00000278637 | breast cancer | 16707467 | |
| ENSG00000278637 | breast cancer | 16861913 | |
| ENSG00000278637 | tumor | 16863736 | |
| ENSG00000278637 | tumor | 1711413 | |
| ENSG00000278637 | pediatric tumors | 17725108 | |
| ENSG00000278637 | cancer | 17729398 | |
| ENSG00000278637 | lung cancer | 18172270 | |
| ENSG00000278637 | tumor | 18187659 | |
| ENSG00000278637 | tumour | 18384290 | |
| ENSG00000278637 | cancer | 18595135 | |
| ENSG00000278637 | cancers | 18701507 | |
| ENSG00000278637 | lung cancer | 18974389 | |
| ENSG00000278637 | cancer | 19056850 | |
| ENSG00000278637 | tumor | 19086847 | |
| ENSG00000278637 | DLBCL | 19438744 | |
| ENSG00000278637 | cancer | 19509260 | |
| ENSG00000278637 | pancreatic cancer | 19582723 | |
| ENSG00000278637 | cancer | 19961487 | |
| ENSG00000278637 | ovarian epithelial tumors | 20057286 | |
| ENSG00000278637 | ovarian cancer | 20111712 | |
| ENSG00000278637 | tumor | 20534538 | |
| ENSG00000278637 | cancer | 21145737 | |
| ENSG00000278637 | breast cancers | 21321083 | |
| ENSG00000278637 | ovarian cancer | 21355783 | |
| ENSG00000278637 | cancer | 21415707 | |
| ENSG00000278637 | AML | 21968610 | |
| ENSG00000278637 | cancer | 22035019 | |
| ENSG00000278637 | cancer | 22260708 | |
| ENSG00000278637 | tumor | 22279574 | |
| ENSG00000278637 | cancer | 22419068 | |
| ENSG00000278637 | tumours | 22569052 | |
| ENSG00000278637 | pancreatic cancer | 22607671 | |
| ENSG00000278637 | tumor | 22720237 | |
| ENSG00000278637 | tumor | 23019525 | |
| ENSG00000278637 | tumor | 23308215 | |
| ENSG00000278637 | prostate cancer | 23524101 | |
| ENSG00000278637 | tumor | 23553687 | |
| ENSG00000278637 | tumor | 23720754 | |
| ENSG00000278637 | cancer | 23826629 | |
| ENSG00000278637 | prostate cancer | 24065480 | |
| ENSG00000278637 | thyroid cancer | 24155971 | |
| ENSG00000278637 | lung cancer | 24283195 | |
| ENSG00000278637 | tumor | 24778322 | |
| ENSG00000278637 | cancer | 24913909 | |
| ENSG00000278637 | prostate cancer | 24937452 | |
| ENSG00000278637 | cancers | 24953066 | |
| ENSG00000278637 | tumor | 25073158 | |
| ENSG00000278637 | pancreatic cancer | 25152840 | |
| ENSG00000278637 | colon cancer | 25451013 | |
| ENSG00000278637 | non-small-cell lung cancer | 25473433 | |
| ENSG00000278637 | tumors | 25512468 | |
| ENSG00000278637 | cancers | 25512710 | |
| ENSG00000278637 | breast tumors | 25814362 | |
| ENSG00000278637 | tumour | 25864732 | |
| ENSG00000278637 | tumors | 25889518 | |
| ENSG00000278637 | tumor | 25954275 | |
| ENSG00000278637 | Endometrial Cancer | 26222483 | |
| ENSG00000278637 | cancers | 26321891 | |
| ENSG00000278637 | tumors | 26929985 | |
| ENSG00000278637 | lung cancer | 27091080 | |
| ENSG00000278637 | prostate cancer | 27268279 | |
| ENSG00000278637 | cancer | 27322556 | |
| ENSG00000278637 | cancer | 27499010 | |
| ENSG00000278637 | cancer | 27994746 | |
| ENSG00000278637 | cancer | 28139737 | |
| ENSG00000278637 | tumor | 28360947 | |
| ENSG00000278637 | Prostate Cancer | 28609657 | |
| ENSG00000278637 | tumors | 28866885 | |
| ENSG00000278637 | cancer | 28874504 | |
| ENSG00000278637 | lung cancer | 29030587 | |
| ENSG00000278637 | prostate cancer | 29069764 | |
| ENSG00000278637 | cervical cancer | 29184082 | |
| ENSG00000278637 | tumor | 29250163 | |
| ENSG00000278637 | tumor | 29308302 | |
| ENSG00000278637 | cancer | 29401749 | |
| ENSG00000278637 | cancer | 29616094 | |
| ENSG00000278637 | breast cancer | 29667342 | |
| ENSG00000278637 | cancers | 29721093 | |
| ENSG00000278637 | breast cancer | 29745061 | |
| ENSG00000278637 | breast cancer | 29759486 | |
| ENSG00000278637 | tumor | 30021196 | |
| ENSG00000278637 | Ovarian cancer | 30394813 | |
| ENSG00000278637 | cervical cancer | 30416981 | |
| ENSG00000278637 | cancer | 30471193 | |
| ENSG00000278637 | ovarian cancer | 30759370 | |
| ENSG00000278637 | cancer | 30807115 | |
| ENSG00000278637 | AML | 30819918 | |
| ENSG00000278637 | childhood cancer | 30929275 | |
| ENSG00000278637 | breast tumors | 30938887 | |
| ENSG00000278637 | pancreatic cancer | 30942624 | |
| ENSG00000278637 | tumour | 31043582 | |
| ENSG00000278637 | prostate cancer | 31061526 | |
| ENSG00000278637 | tumors | 31137727 | |
| ENSG00000278637 | bladder cancer | 31217782 | |
| ENSG00000278637 | breast cancer | 31219579 | |
| ENSG00000278637 | pancreatic tumor | 31312365 | |
| ENSG00000278637 | Colon Cancer | 31471419 | |
| ENSG00000278637 | Cancer | 31575549 | |
| ENSG00000278637 | tumors | 31608230 | |
| ENSG00000278637 | tumor | 31665067 | |
| ENSG00000278637 | lung cancer | 31737580 | |
| ENSG00000278637 | cancer | 31903140 | |
| ENSG00000278637 | pituitary tumor | 8232763 | |
| ENSG00000278637 | tumors | 8668193 | |
| ENSG00000278637 | tumor | 8816806 | |
| ENSG00000278637 | tumor | 9472111 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000278637 | MESO | 3e-04 | high | ||
| ENSG00000278637 | UVM | 0.042 | high | ||
| ENSG00000278637 | UCEC | 0.025 | low | ||
| ENSG00000278637 | ACC | 0.0016 | high | ||
| ENSG00000278637 | LGG | 0.0018 | high | ||
| ENSG00000278637 | HNSC | 0.024 | low | ||
| ENSG00000278637 | KICH | 0.00064 | high | ||
| ENSG00000278637 | LUAD | 0.043 | high | ||
| ENSG00000278637 | THYM | 0.0018 | low | ||
| ENSG00000278637 | BRCA | 0.017 | high | ||
| ENSG00000278637 | COAD | 0.026 | low | ||
| ENSG00000278637 | OV | 0.0019 | low | ||
| ENSG00000278637 | DLBC | 0.022 | low | ||
| ENSG00000278637 | KIRC | 0.0083 | high | ||
| ENSG00000278637 | SKCM | 0.018 | high |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|---|---|---|---|---|---|---|
| ENSG00000278637 | ESCA | Del | 1.105836 | 0.108265 | 0.379032 | 0.266304 | |
| ENSG00000278637 | SKCM | Amp | 2.531068 | 0.176440 | 0.749660 | 0.523161 | |
| ENSG00000278637 | LIHC | Amp | 1.403237 | 0.132038 | 0.741473 | 0.408108 | |
| ENSG00000278637 | BLCA | Amp | 3.087502 | 0.241656 | 0.573650 | 0.294118 | |
| ENSG00000278637 | UVM | Amp | 2.348192 | 0.265094 | 1.138665 | 0.550000 | |
| ENSG00000278637 | OV | Amp | 3.395858 | 0.413298 | 0.714270 | 0.483592 |