Ensembl ID ENSG00000277157 Gene ID 8360 Accession 4782
Gene Symbol H4C4 Alias H4/b;H4C1;H4C2;H4C3;H4C5;H4C6;H4C8;H4C9;H4FB;H4-16;H4C11;H4C12;H4C13;H4C14;H4C15;H4C16;HIST1H4D;dJ221C16.9 Full Name H4 clustered histone 4
Position 6 : 26188710 - 26189112 Length 403 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

ENSG00000277157 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000277157 3.63 2.10e-65 BRCA
ENSG00000277157 3.62 4.71e-16 COAD
ENSG00000277157 2.49 1.12e-23 LUSC
ENSG00000277157 1.99 3.88e-20 PRAD
ENSG00000277157 2.93 2.53e-24 UCEC
ENSG00000277157 3.88 7.68e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000277157 tumors 10344733
ENSG00000277157 tumour 10376979
ENSG00000277157 breast cancer 11682064
ENSG00000277157 Skin tumors 11782361
ENSG00000277157 tumor 12385581
ENSG00000277157 tumor 12579268
ENSG00000277157 gastric cancer 12677198
ENSG00000277157 tumor 12724227
ENSG00000277157 cancer 12865631
ENSG00000277157 Tumor 12891711
ENSG00000277157 tumor 12939461
ENSG00000277157 colon cancer 12975486
ENSG00000277157 tumours 14614037
ENSG00000277157 cancer 15095300
ENSG00000277157 cancer 15765097
ENSG00000277157 cancer 16131487
ENSG00000277157 tumors 16205112
ENSG00000277157 tumor 16254189
ENSG00000277157 tumors 16270534
ENSG00000277157 breast cancer 16322686
ENSG00000277157 tumours 16404435
ENSG00000277157 tumor 1644858
ENSG00000277157 tumor 16488987
ENSG00000277157 liver tumors 16497704
ENSG00000277157 cancer 16699174
ENSG00000277157 breast cancer 16707467
ENSG00000277157 breast cancer 16861913
ENSG00000277157 tumor 16863736
ENSG00000277157 tumor 1711413
ENSG00000277157 pediatric tumors 17725108
ENSG00000277157 cancer 17729398
ENSG00000277157 lung cancer 18172270
ENSG00000277157 tumor 18187659
ENSG00000277157 tumour 18384290
ENSG00000277157 cancer 18595135
ENSG00000277157 cancers 18701507
ENSG00000277157 lung cancer 18974389
ENSG00000277157 cancer 19056850
ENSG00000277157 tumor 19086847
ENSG00000277157 DLBCL 19438744
ENSG00000277157 cancer 19509260
ENSG00000277157 pancreatic cancer 19582723
ENSG00000277157 cancer 19961487
ENSG00000277157 ovarian epithelial tumors 20057286
ENSG00000277157 ovarian cancer 20111712
ENSG00000277157 tumor 20534538
ENSG00000277157 cancer 21145737
ENSG00000277157 breast cancers 21321083
ENSG00000277157 ovarian cancer 21355783
ENSG00000277157 cancer 21415707
ENSG00000277157 AML 21968610
ENSG00000277157 cancer 22035019
ENSG00000277157 cancer 22260708
ENSG00000277157 tumor 22279574
ENSG00000277157 cancer 22419068
ENSG00000277157 tumours 22569052
ENSG00000277157 pancreatic cancer 22607671
ENSG00000277157 tumor 22720237
ENSG00000277157 tumor 23019525
ENSG00000277157 tumor 23308215
ENSG00000277157 prostate cancer 23524101
ENSG00000277157 tumor 23553687
ENSG00000277157 tumor 23720754
ENSG00000277157 cancer 23826629
ENSG00000277157 prostate cancer 24065480
ENSG00000277157 thyroid cancer 24155971
ENSG00000277157 lung cancer 24283195
ENSG00000277157 tumor 24778322
ENSG00000277157 cancer 24913909
ENSG00000277157 prostate cancer 24937452
ENSG00000277157 cancers 24953066
ENSG00000277157 tumor 25073158
ENSG00000277157 pancreatic cancer 25152840
ENSG00000277157 colon cancer 25451013
ENSG00000277157 non-small-cell lung cancer 25473433
ENSG00000277157 tumors 25512468
ENSG00000277157 cancers 25512710
ENSG00000277157 cancer 25814362
ENSG00000277157 tumour 25864732
ENSG00000277157 tumors 25889518
ENSG00000277157 tumor 25954275
ENSG00000277157 Endometrial Cancer 26222483
ENSG00000277157 cancers 26321891
ENSG00000277157 tumors 26929985
ENSG00000277157 lung cancer 27091080
ENSG00000277157 prostate cancer 27268279
ENSG00000277157 cancer 27322556
ENSG00000277157 cancer 27499010
ENSG00000277157 cancer 27994746
ENSG00000277157 cancer 28139737
ENSG00000277157 tumor 28360947
ENSG00000277157 Prostate Cancer 28609657
ENSG00000277157 tumors 28866885
ENSG00000277157 cancer 28874504
ENSG00000277157 lung cancer 29030587
ENSG00000277157 prostate cancer 29069764
ENSG00000277157 cervical cancer 29184082
ENSG00000277157 tumor 29250163
ENSG00000277157 tumor 29308302
ENSG00000277157 cancer 29401749
ENSG00000277157 cancer 29616094
ENSG00000277157 breast cancer 29667342
ENSG00000277157 cancers 29721093
ENSG00000277157 breast cancer 29745061
ENSG00000277157 breast cancer 29759486
ENSG00000277157 tumor 30021196
ENSG00000277157 Ovarian cancer 30394813
ENSG00000277157 cervical cancer 30416981
ENSG00000277157 cancer 30471193
ENSG00000277157 ovarian cancer 30759370
ENSG00000277157 cancer 30807115
ENSG00000277157 AML 30819918
ENSG00000277157 childhood cancer 30929275
ENSG00000277157 breast tumors 30938887
ENSG00000277157 pancreatic cancer 30942624
ENSG00000277157 tumour 31043582
ENSG00000277157 prostate cancer 31061526
ENSG00000277157 tumors 31137727
ENSG00000277157 bladder cancer 31217782
ENSG00000277157 breast cancer 31219579
ENSG00000277157 cancer 31312365
ENSG00000277157 Colon Cancer 31471419
ENSG00000277157 Cancer 31575549
ENSG00000277157 tumors 31608230
ENSG00000277157 tumor 31665067
ENSG00000277157 lung cancer 31737580
ENSG00000277157 cancer 31903140
ENSG00000277157 pituitary tumor 8232763
ENSG00000277157 tumors 8668193
ENSG00000277157 tumor 8816806
ENSG00000277157 tumor 9472111
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000277157 MESO 0.024 high
ENSG00000277157 SARC 0.0044 high
ENSG00000277157 CHOL 0.0092 low
ENSG00000277157 PAAD 0.031 low
ENSG00000277157 UCEC 0.017 low
ENSG00000277157 THCA 0.03 low
ENSG00000277157 ACC 0.0039 high
ENSG00000277157 PCPG 0.016 low
ENSG00000277157 THYM 0.00053 low
ENSG00000277157 COAD 0.047 high
ENSG00000277157 UCS 0.025 low
ENSG00000277157 ESCA 0.0013 high
ENSG00000277157 OV 0.044 low
ENSG00000277157 KIRC 0.0023 high
ENSG00000277157 PRAD 0.037 low
ENSG00000277157 TGCT 0.048 low
ENSG00000277157 BLCA 0.0083 low
ENSG00000277157 LAML 0.018 high
ENSG00000277157 GBM 0.01 high
ENSG00000277157 SKCM 0.029 high
ENSG00000277157 CESC 0.016 low
ENSG00000277157 LIHC 0.0059 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000277157 ESCA Del 1.634155 0.122975 0.381049 0.277174
ENSG00000277157 SKCM Amp 2.215015 0.167852 0.743132 0.523161
ENSG00000277157 LIHC Amp 1.260465 0.128199 0.743134 0.405405
ENSG00000277157 BLCA Amp 2.415104 0.222480 0.548336 0.291667
ENSG00000277157 UVM Amp 1.976306 0.243776 1.148270 0.537500
ENSG00000277157 OV Amp 2.217248 0.380994 0.702375 0.471503