Ensembl ID ENSG00000276966 Gene ID 8367 Accession 4790
Gene Symbol H4C5 Alias H4/j;H4C1;H4C2;H4C3;H4C4;H4C6;H4C8;H4C9;H4FJ;H4-16;H4C11;H4C12;H4C13;H4C14;H4C15;H4C16;HIST1H4E;TEVANED3;TEBIVANED3 Full Name H4 clustered histone 5
Position 6 : 26204610 - 26205021 Length 412 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

ENSG00000276966 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000276966 2.01 1.15e-17 KIRC
ENSG00000276966 1.61 2.01e-13 HNSC
ENSG00000276966 3.45 1.24e-13 BLCA
ENSG00000276966 3.30 3.28e-61 BRCA
ENSG00000276966 2.92 3.23e-16 COAD
ENSG00000276966 2.87 1.78e-37 LUSC
ENSG00000276966 2.13 3.68e-19 PRAD
ENSG00000276966 2.51 2.47e-16 LIHC
ENSG00000276966 2.94 1.88e-27 UCEC
ENSG00000276966 3.80 1.27e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000276966 tumors 10344733
ENSG00000276966 tumour 10376979
ENSG00000276966 breast cancer 11682064
ENSG00000276966 Skin tumors 11782361
ENSG00000276966 tumor 12385581
ENSG00000276966 tumor 12579268
ENSG00000276966 gastric cancer 12677198
ENSG00000276966 colorectal cancers 12724227
ENSG00000276966 cancer 12865631
ENSG00000276966 Tumor 12891711
ENSG00000276966 tumor 12939461
ENSG00000276966 colon cancer 12975486
ENSG00000276966 tumours 14614037
ENSG00000276966 cancer 15095300
ENSG00000276966 cancer 15765097
ENSG00000276966 cancer 16131487
ENSG00000276966 tumors 16205112
ENSG00000276966 tumor 16254189
ENSG00000276966 tumors 16270534
ENSG00000276966 breast cancer 16322686
ENSG00000276966 cancer 16404435
ENSG00000276966 tumor 1644858
ENSG00000276966 tumor 16488987
ENSG00000276966 tumor 16497704
ENSG00000276966 tumor 16699174
ENSG00000276966 breast cancer 16707467
ENSG00000276966 breast cancer 16861913
ENSG00000276966 tumor 16863736
ENSG00000276966 tumor 1711413
ENSG00000276966 pediatric tumors 17725108
ENSG00000276966 cancer 17729398
ENSG00000276966 lung cancer 18172270
ENSG00000276966 prostate cancer 18187659
ENSG00000276966 tumour 18384290
ENSG00000276966 cancer 18595135
ENSG00000276966 cancers 18701507
ENSG00000276966 cancer 18974389
ENSG00000276966 cancer 19056850
ENSG00000276966 tumor 19086847
ENSG00000276966 DLBCL 19438744
ENSG00000276966 cancer 19509260
ENSG00000276966 pancreatic cancer 19582723
ENSG00000276966 cancer 19961487
ENSG00000276966 ovarian epithelial tumors 20057286
ENSG00000276966 ovarian cancer 20111712
ENSG00000276966 tumor 20534538
ENSG00000276966 cancer 21145737
ENSG00000276966 breast cancers 21321083
ENSG00000276966 ovarian cancer 21355783
ENSG00000276966 cancer 21415707
ENSG00000276966 AML 21968610
ENSG00000276966 cancer 22035019
ENSG00000276966 cancer 22260708
ENSG00000276966 tumor 22279574
ENSG00000276966 cancer 22419068
ENSG00000276966 tumours 22569052
ENSG00000276966 pancreatic cancer 22607671
ENSG00000276966 tumor 22720237
ENSG00000276966 tumor 23019525
ENSG00000276966 tumor 23308215
ENSG00000276966 prostate cancer 23524101
ENSG00000276966 tumor 23553687
ENSG00000276966 tumor 23720754
ENSG00000276966 cancer 23826629
ENSG00000276966 prostate cancer 24065480
ENSG00000276966 thyroid cancer 24155971
ENSG00000276966 lung cancer 24283195
ENSG00000276966 tumor 24778322
ENSG00000276966 cancer 24913909
ENSG00000276966 prostate cancer 24937452
ENSG00000276966 cancers 24953066
ENSG00000276966 tumor 25073158
ENSG00000276966 pancreatic cancer 25152840
ENSG00000276966 colon cancer 25451013
ENSG00000276966 non-small-cell lung cancer 25473433
ENSG00000276966 tumors 25512468
ENSG00000276966 cancers 25512710
ENSG00000276966 breast tumors 25814362
ENSG00000276966 tumour 25864732
ENSG00000276966 tumors 25889518
ENSG00000276966 tumor 25954275
ENSG00000276966 Endometrial Cancer 26222483
ENSG00000276966 cancers 26321891
ENSG00000276966 tumors 26929985
ENSG00000276966 lung cancer 27091080
ENSG00000276966 prostate cancer 27268279
ENSG00000276966 cancer 27322556
ENSG00000276966 cancer 27499010
ENSG00000276966 cancer 27994746
ENSG00000276966 cancer 28139737
ENSG00000276966 tumor 28360947
ENSG00000276966 Prostate Cancer 28609657
ENSG00000276966 tumors 28866885
ENSG00000276966 cancer 28874504
ENSG00000276966 lung cancer 29030587
ENSG00000276966 prostate cancer 29069764
ENSG00000276966 cervical cancer 29184082
ENSG00000276966 tumor 29250163
ENSG00000276966 tumor 29308302
ENSG00000276966 cancer 29401749
ENSG00000276966 cancer 29616094
ENSG00000276966 breast cancer 29667342
ENSG00000276966 cancers 29721093
ENSG00000276966 breast cancer 29745061
ENSG00000276966 breast cancer 29759486
ENSG00000276966 tumor 30021196
ENSG00000276966 cancer 30394813
ENSG00000276966 cervical cancer 30416981
ENSG00000276966 cancer 30471193
ENSG00000276966 ovarian cancer 30759370
ENSG00000276966 cancer 30807115
ENSG00000276966 AML 30819918
ENSG00000276966 childhood cancer 30929275
ENSG00000276966 breast tumors 30938887
ENSG00000276966 pancreatic cancer 30942624
ENSG00000276966 tumour 31043582
ENSG00000276966 prostate cancer 31061526
ENSG00000276966 tumors 31137727
ENSG00000276966 bladder cancer 31217782
ENSG00000276966 breast cancer 31219579
ENSG00000276966 pancreatic tumor 31312365
ENSG00000276966 Colon Cancer 31471419
ENSG00000276966 Cancer 31575549
ENSG00000276966 tumors 31608230
ENSG00000276966 tumor 31665067
ENSG00000276966 lung cancer 31737580
ENSG00000276966 cancer 31903140
ENSG00000276966 pituitary tumor 8232763
ENSG00000276966 tumors 8668193
ENSG00000276966 tumor 8816806
ENSG00000276966 tumor 9472111
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000276966 MESO 0.032 low
ENSG00000276966 SARC 0.00059 high
ENSG00000276966 STAD 0.0089 low
ENSG00000276966 UVM 0.016 low
ENSG00000276966 PAAD 0.003 low
ENSG00000276966 LGG 0.017 high
ENSG00000276966 LUSC 0.024 low
ENSG00000276966 KIRP 0.0042 high
ENSG00000276966 THYM 0.019 low
ENSG00000276966 COAD 0.01 high
ENSG00000276966 UCS 0.0026 high
ENSG00000276966 ESCA 0.043 high
ENSG00000276966 KIRC 0.00047 high
ENSG00000276966 BLCA 0.026 low
ENSG00000276966 LAML 0.0017 low
ENSG00000276966 CESC 0.048 low
ENSG00000276966 LIHC 0.0067 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000276966 PAAD Del 2.847890 0.084141 0.336799 0.375000
ENSG00000276966 ESCA Del 1.634155 0.122975 0.381049 0.277174
ENSG00000276966 SKCM Amp 2.215015 0.167852 0.743132 0.523161
ENSG00000276966 LIHC Amp 1.048142 0.121991 0.737044 0.405405
ENSG00000276966 BLCA Amp 2.508805 0.225170 0.552003 0.291667
ENSG00000276966 UVM Amp 1.976306 0.243776 1.148270 0.537500
ENSG00000276966 OV Amp 2.289747 0.383079 0.700499 0.474957