Ensembl ID ENSG00000275700 Gene ID 26574 Accession 19235
Gene Symbol AATF Alias DED;BFR2;CHE1;CHE-1 Full Name apoptosis antagonizing transcription factor
Position 17 : 36948925 - 37056871 Length 107947 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

ENSG00000275700 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000275700 AATF 0.42 3.26e-17 KIRC
ENSG00000275700 AATF 0.68 1.04e-17 HNSC
ENSG00000275700 AATF 0.63 2.45e-25 BRCA
ENSG00000275700 AATF 0.68 7.59e-17 COAD
ENSG00000275700 AATF 0.56 1.69e-13 LUSC
ENSG00000275700 AATF 0.62 1.60e-16 LIHC
ENSG00000275700 AATF 0.51 3.50e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000275700 AATF tumor 14761944
ENSG00000275700 AATF tumor 15069192
ENSG00000275700 AATF tumor 19668227
ENSG00000275700 AATF tumor 19924290
ENSG00000275700 AATF breast cancer 20025740
ENSG00000275700 AATF tumor 20924650
ENSG00000275700 AATF tumour 22190004
ENSG00000275700 AATF endometrial cancers 22909821
ENSG00000275700 AATF tumor 22983126
ENSG00000275700 AATF tumor 23146908
ENSG00000275700 AATF breast cancer 23801113
ENSG00000275700 AATF tumor 23935974
ENSG00000275700 AATF cancer 25231211
ENSG00000275700 AATF cancer 25914721
ENSG00000275700 AATF cancer 26313917
ENSG00000275700 AATF tumors 26913241
ENSG00000275700 AATF lung cancer 2750081
ENSG00000275700 AATF malignant tumor 27599843
ENSG00000275700 AATF cancer 28214471
ENSG00000275700 AATF cancer 28622443
ENSG00000275700 AATF tumor 29130107
ENSG00000275700 AATF tumor 29140741
ENSG00000275700 AATF cancer 29232376
ENSG00000275700 AATF lung cancer 29321668
ENSG00000275700 AATF tumor 29367285
ENSG00000275700 AATF Wilms' tumor 30338213
ENSG00000275700 AATF cancers 30526315
ENSG00000275700 AATF tumor 30673862
ENSG00000275700 AATF tumor 31152681
ENSG00000275700 AATF cancer 31363146
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000275700 AATF MESO 0.03 high
ENSG00000275700 AATF STAD 0.026 low
ENSG00000275700 AATF CHOL 0.011 high
ENSG00000275700 AATF PAAD 0.028 high
ENSG00000275700 AATF UCEC 0.0038 high
ENSG00000275700 AATF THCA 0.011 high
ENSG00000275700 AATF ACC 0.00013 high
ENSG00000275700 AATF HNSC 0.017 high
ENSG00000275700 AATF READ 0.0013 low
ENSG00000275700 AATF KICH 0.00078 high
ENSG00000275700 AATF LUAD 0.0049 high
ENSG00000275700 AATF PCPG 0.02 high
ENSG00000275700 AATF THYM 0.029 low
ENSG00000275700 AATF BRCA 0.0072 low
ENSG00000275700 AATF KIRC 0.025 high
ENSG00000275700 AATF PRAD 0.049 low
ENSG00000275700 AATF BLCA 0.012 high
ENSG00000275700 AATF SKCM 0.016 high
ENSG00000275700 AATF CESC 0.0039 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000275700 AATF ACC Del 1.014407 0.110671 0.564267 0.277778
ENSG00000275700 AATF COAD Amp 1.821999 0.089737 0.525894 0.230599
ENSG00000275700 AATF SARC Del 0.912802 0.127643 0.421641 0.256809
ENSG00000275700 AATF PCPG Del 5.314186 0.134997 0.650515 0.228395
ENSG00000275700 AATF BRCA Amp 3.033493 0.185873 0.679084 0.217593
ENSG00000275700 AATF BRCA Del 3.834029 0.086311 0.431230 0.321296
ENSG00000275700 AATF STAD Amp 4.141108 0.219548 0.534365 0.238095
ENSG00000275700 AATF UCEC Del 3.042522 0.072913 0.585568 0.194805