Ensembl ID ENSG00000273749 Gene ID 23191 Accession 13759
Gene Symbol CYFIP1 Alias SHYC;SRA1;SRA-1;P140SRA-1 Full Name cytoplasmic FMR1 interacting protein 1
Position 15 : 22867052 - 22981063 Length 114012 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, Mar 2022]

ENSG00000273749 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000273749 tumors 19524508
ENSG00000273749 cancers 19573806
ENSG00000273749 Cancer 25906751
ENSG00000273749 Cancer 26676744
ENSG00000273749 Breast Cancer 27432794
ENSG00000273749 cancer 27527252
ENSG00000273749 cancers 28410392
ENSG00000273749 tumor 29534591
ENSG00000273749 breast cancer 29706651
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000273749 SARC 0.015 low
ENSG00000273749 CHOL 0.037 low
ENSG00000273749 UVM 0.0078 high
ENSG00000273749 UCEC 0.011 low
ENSG00000273749 ACC 0.00083 high
ENSG00000273749 LUSC 0.0099 high
ENSG00000273749 READ 0.02 low
ENSG00000273749 KIRP 0.0055 low
ENSG00000273749 LUAD 0.0061 high
ENSG00000273749 PCPG 0.043 high
ENSG00000273749 THYM 0.0023 high
ENSG00000273749 BRCA 0.0016 high
ENSG00000273749 COAD 0.028 high
ENSG00000273749 PRAD 0.024 high
ENSG00000273749 BLCA 0.0025 high
ENSG00000273749 LAML 0.046 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency