Ensembl ID ENSG00000271425 Gene ID 100132406 Accession 31992
Gene Symbol NBPF10 Alias AB6;AG1;NBPF9 Full Name NBPF member 10
Position 1 : 146064711 - 146229000 Length 164290 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

ENSG00000271425 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000271425 GBM 24967941
ENSG00000271425 breast cancers 29879995
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000271425 PAAD 0.014 high
ENSG00000271425 UCEC 0.0033 high
ENSG00000271425 LGG 0.036 high
ENSG00000271425 HNSC 0.0052 low
ENSG00000271425 KICH 0.0048 high
ENSG00000271425 THYM 0.0046 high
ENSG00000271425 COAD 0.017 high
ENSG00000271425 ESCA 0.0091 high
ENSG00000271425 PRAD 0.043 high
ENSG00000271425 LAML 0.024 high
ENSG00000271425 SKCM 0.031 low
ENSG00000271425 CESC 0.045 high
ENSG00000271425 LIHC 0.0052 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency