Ensembl ID ENSG00000258818 Gene ID 6038 Accession 10047
Gene Symbol RNASE4 Alias RAB1;RNS4 Full Name ribonuclease A family member 4
Position 14 : 20684560 - 20701216 Length 16657 bases Strand Plus strand
Status Confidence Main interacting RNAsdiverseRBP type Canonical_RBPs
Summary The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013]

ENSG00000258818 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000258818 RNASE4 1.01 1.99e-16 KIRC
ENSG00000258818 RNASE4 -1.5 1.31e-20 HNSC
ENSG00000258818 RNASE4 -1.9 3.12e-13 BLCA
ENSG00000258818 RNASE4 -1.2 1.35e-30 BRCA
ENSG00000258818 RNASE4 -3.2 6.98e-50 KICH
ENSG00000258818 RNASE4 -2.3 1.35e-63 LUSC
ENSG00000258818 RNASE4 -2.2 4.46e-17 UCEC
ENSG00000258818 RNASE4 -3.2 8.10e-16 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000258818 RNASE4 cancers 24659782
ENSG00000258818 RNASE4 skin tumors 30925905
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000258818 RNASE4 MESO 0.0059 low
ENSG00000258818 RNASE4 SARC 0.00091 low
ENSG00000258818 RNASE4 STAD 0.011 high
ENSG00000258818 RNASE4 CHOL 0.031 high
ENSG00000258818 RNASE4 UVM 0.0023 low
ENSG00000258818 RNASE4 PAAD 0.014 low
ENSG00000258818 RNASE4 UCEC 0.00028 low
ENSG00000258818 RNASE4 ACC 0.0063 high
ENSG00000258818 RNASE4 KIRP 0.031 high
ENSG00000258818 RNASE4 KICH 0.01 high
ENSG00000258818 RNASE4 THYM 0.022 high
ENSG00000258818 RNASE4 COAD 0.011 low
ENSG00000258818 RNASE4 OV 0.039 low
ENSG00000258818 RNASE4 DLBC 0.019 high
ENSG00000258818 RNASE4 KIRC 0.0016 low
ENSG00000258818 RNASE4 BLCA 0.04 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000258818 RNASE4 LUSC Del 1.083513 0.071312 0.355895 0.341317
ENSG00000258818 RNASE4 LUAD Amp 1.610736 0.140736 0.431110 0.323643
ENSG00000258818 RNASE4 KIRP Del 1.122031 0.031201 0.551124 0.170139
ENSG00000258818 RNASE4 ACC Amp 0.908712 0.273335 1.099683 0.300000
ENSG00000258818 RNASE4 READ Del 1.003302 0.080707 0.491898 0.418182
ENSG00000258818 RNASE4 GBM Del 5.514048 0.096444 0.599339 0.294627
ENSG00000258818 RNASE4 PAAD Del 0.945689 0.050602 0.405273 0.103261
ENSG00000258818 RNASE4 HNSC Del 0.800630 0.055377 0.414712 0.130268
ENSG00000258818 RNASE4 OV Amp 3.842798 0.424459 0.817972 0.250432