Ensembl ID
ENSG00000258818
Gene ID
6038
Accession
10047
Gene Symbol
RNASE4
Alias
RAB1;RNS4
Full Name
ribonuclease A family member 4
Position
14 : 20684560 - 20701216
Length
16657 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs diverse RBP type
Canonical_RBPs
Summary
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013]
ENSG00000258818 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000258818
RNASE4
1.01
1.99e-16
KIRC
ENSG00000258818
RNASE4
-1.5
1.31e-20
HNSC
ENSG00000258818
RNASE4
-1.9
3.12e-13
BLCA
ENSG00000258818
RNASE4
-1.2
1.35e-30
BRCA
ENSG00000258818
RNASE4
-3.2
6.98e-50
KICH
ENSG00000258818
RNASE4
-2.3
1.35e-63
LUSC
ENSG00000258818
RNASE4
-2.2
4.46e-17
UCEC
ENSG00000258818
RNASE4
-3.2
8.10e-16
CHOL
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000258818
RNASE4
cancers
24659782
ENSG00000258818
RNASE4
skin tumors
30925905
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000258818
RNASE4
MESO
0.0059
low
show
ENSG00000258818
RNASE4
SARC
0.00091
low
show
ENSG00000258818
RNASE4
STAD
0.011
high
show
ENSG00000258818
RNASE4
CHOL
0.031
high
show
ENSG00000258818
RNASE4
UVM
0.0023
low
show
ENSG00000258818
RNASE4
PAAD
0.014
low
show
ENSG00000258818
RNASE4
UCEC
0.00028
low
show
ENSG00000258818
RNASE4
ACC
0.0063
high
show
ENSG00000258818
RNASE4
KIRP
0.031
high
show
ENSG00000258818
RNASE4
KICH
0.01
high
show
ENSG00000258818
RNASE4
THYM
0.022
high
show
ENSG00000258818
RNASE4
COAD
0.011
low
show
ENSG00000258818
RNASE4
OV
0.039
low
show
ENSG00000258818
RNASE4
DLBC
0.019
high
show
ENSG00000258818
RNASE4
KIRC
0.0016
low
show
ENSG00000258818
RNASE4
BLCA
0.04
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000258818
RNASE4
LUSC
Del
1.083513
0.071312
0.355895
0.341317
ENSG00000258818
RNASE4
LUAD
Amp
1.610736
0.140736
0.431110
0.323643
ENSG00000258818
RNASE4
KIRP
Del
1.122031
0.031201
0.551124
0.170139
ENSG00000258818
RNASE4
ACC
Amp
0.908712
0.273335
1.099683
0.300000
ENSG00000258818
RNASE4
READ
Del
1.003302
0.080707
0.491898
0.418182
ENSG00000258818
RNASE4
GBM
Del
5.514048
0.096444
0.599339
0.294627
ENSG00000258818
RNASE4
PAAD
Del
0.945689
0.050602
0.405273
0.103261
ENSG00000258818
RNASE4
HNSC
Del
0.800630
0.055377
0.414712
0.130268
ENSG00000258818
RNASE4
OV
Amp
3.842798
0.424459
0.817972
0.250432
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