Ensembl ID ENSG00000256463 Gene ID 27164 Accession 10527
Gene Symbol SALL3 Alias ZNF796 Full Name spalt like transcription factor 3
Position 18 : 78979818 - 79002677 Length 22860 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011]

ENSG00000256463 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000256463 SALL3 2.68 2.78e-24 BRCA
ENSG00000256463 SALL3 7.03 9.09e-34 LUSC
ENSG00000256463 SALL3 4.35 3.29e-18 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000256463 SALL3 bladder cancer 18094410
ENSG00000256463 SALL3 pancreatic cancer 18332107
ENSG00000256463 SALL3 cancer 19139273
ENSG00000256463 SALL3 cancers 20184741
ENSG00000256463 SALL3 cancer 23143597
ENSG00000256463 SALL3 colon cancer 25774687
ENSG00000256463 SALL3 Cervical Cancer 26697877
ENSG00000256463 SALL3 cancer 28077797
ENSG00000256463 SALL3 HNSCC 28616099
ENSG00000256463 SALL3 lung cancer 29514626
ENSG00000256463 SALL3 tumor 29581773
ENSG00000256463 SALL3 tumors 29587736
ENSG00000256463 SALL3 cervical cancer 29850477
ENSG00000256463 SALL3 Cancer 30901947
ENSG00000256463 SALL3 cervical cancer 31271297
ENSG00000256463 SALL3 Cervical Cancer 31699190
ENSG00000256463 SALL3 cancer 31746370
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000256463 SALL3 MESO 0.0068 high
ENSG00000256463 SALL3 SARC 0.046 high
ENSG00000256463 SALL3 UVM 0.0051 high
ENSG00000256463 SALL3 PAAD 0.03 low
ENSG00000256463 SALL3 UCEC 0.00029 high
ENSG00000256463 SALL3 THCA 6e-04 high
ENSG00000256463 SALL3 ACC 0.029 high
ENSG00000256463 SALL3 HNSC 0.017 low
ENSG00000256463 SALL3 KIRP 0.012 high
ENSG00000256463 SALL3 LUAD 0.028 low
ENSG00000256463 SALL3 THYM 0.015 low
ENSG00000256463 SALL3 BRCA 0.044 low
ENSG00000256463 SALL3 KIRC 0.0046 high
ENSG00000256463 SALL3 LAML 0.0071 low
ENSG00000256463 SALL3 GBM 0.015 low
ENSG00000256463 SALL3 SKCM 0.013 high
ENSG00000256463 SALL3 CESC 0.0034 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000256463 SALL3 LUSC Del 7.953142 0.136142 0.391672 0.459082
ENSG00000256463 SALL3 LUAD Del 7.064499 0.107426 0.381935 0.480620
ENSG00000256463 SALL3 LGG Del 1.298014 0.045585 0.451284 0.146199
ENSG00000256463 SALL3 READ Del 5.252556 0.158133 0.655056 0.854545
ENSG00000256463 SALL3 COAD Del 6.365332 0.090021 0.617637 0.629712
ENSG00000256463 SALL3 SARC Del 0.656917 0.118375 0.482057 0.322957
ENSG00000256463 SALL3 PAAD Del 0.945689 0.051191 0.394110 0.652174
ENSG00000256463 SALL3 ESCA Del 4.226930 0.183580 0.474572 0.592391
ENSG00000256463 SALL3 HNSC Del 26.061164 0.201804 0.446577 0.553640
ENSG00000256463 SALL3 TGCT Del 2.671455 0.098882 0.391173 0.833333
ENSG00000256463 SALL3 BLCA Del 3.718164 0.119941 0.444813 0.436275
ENSG00000256463 SALL3 BRCA Del 4.822087 0.091725 0.445273 0.330556
ENSG00000256463 SALL3 STAD Del 12.408571 0.160802 0.438398 0.439909
ENSG00000256463 SALL3 PRAD Del 4.220766 0.108925 0.490774 0.278455
ENSG00000256463 SALL3 UCEC Del 5.388841 0.091393 0.537063 0.183673
ENSG00000256463 SALL3 OV Del 28.757240 0.442222 0.671379 0.658031