Ensembl ID
ENSG00000254093
Gene ID
54984
Accession
30046
Gene Symbol
PINX1
Alias
Gno1;LPTL;LPTS;Pxr1
Full Name
PIN2 (TERF1) interacting telomerase inhibitor 1
Position
8 : 10764961 - 10839876
Length
74916 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
Enables telomerase RNA binding activity and telomerase inhibitor activity. Involved in several processes, including negative regulation of DNA biosynthetic process; positive regulation of protein localization to nucleolus; and protein localization to organelle. Acts upstream of or within telomere maintenance via telomerase. Located in several cellular components, including chromosomal region; nuclear lumen; and spindle. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000254093 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000254093
PINX1
tumor
11867205
ENSG00000254093
PINX1
neck tumor
12508358
ENSG00000254093
PINX1
liver cancer
12561469
ENSG00000254093
PINX1
tumor
14984932
ENSG00000254093
PINX1
cancer
15181449
ENSG00000254093
PINX1
hereditary prostate cancer
15264240
ENSG00000254093
PINX1
tumor
15637589
ENSG00000254093
PINX1
gastric cancer
18784941
ENSG00000254093
PINX1
tumor
20816839
ENSG00000254093
PINX1
bladder cancer
22363464
ENSG00000254093
PINX1
cancer
24349080
ENSG00000254093
PINX1
Tumor
25479038
ENSG00000254093
PINX1
breast cancer
26187699
ENSG00000254093
PINX1
cancers
27221889
ENSG00000254093
PINX1
epithelial ovarian cancer
28233473
ENSG00000254093
PINX1
cancer
29017500
ENSG00000254093
PINX1
tumor
30026037
ENSG00000254093
PINX1
Tumors
30079348
ENSG00000254093
PINX1
cancer
31027734
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000254093
PINX1
MESO
0.00043
high
show
ENSG00000254093
PINX1
SARC
0.042
low
show
ENSG00000254093
PINX1
UVM
0.017
high
show
ENSG00000254093
PINX1
UCEC
0.016
low
show
ENSG00000254093
PINX1
ACC
0.037
low
show
ENSG00000254093
PINX1
LGG
0.00058
high
show
ENSG00000254093
PINX1
LUSC
0.014
low
show
ENSG00000254093
PINX1
READ
0.049
low
show
ENSG00000254093
PINX1
LUAD
0.0046
high
show
ENSG00000254093
PINX1
PCPG
0.039
low
show
ENSG00000254093
PINX1
COAD
0.011
low
show
ENSG00000254093
PINX1
ESCA
0.011
low
show
ENSG00000254093
PINX1
DLBC
0.02
low
show
ENSG00000254093
PINX1
KIRC
0.037
low
show
ENSG00000254093
PINX1
BLCA
0.028
high
show
ENSG00000254093
PINX1
SKCM
0.0071
high
show
ENSG00000254093
PINX1
LIHC
0.0034
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000254093
PINX1
LUSC
Del
5.518537
0.117773
0.458815
0.660679
ENSG00000254093
PINX1
LUAD
Del
1.676203
0.063784
0.455332
0.501938
ENSG00000254093
PINX1
READ
Del
6.797937
0.181754
0.678564
0.593939
ENSG00000254093
PINX1
COAD
Del
6.404302
0.090261
0.680804
0.432373
ENSG00000254093
PINX1
UCS
Del
1.145886
0.239730
0.716076
0.553571
ENSG00000254093
PINX1
PAAD
Del
0.602811
0.042953
0.396998
0.320652
ENSG00000254093
PINX1
ESCA
Amp
2.579603
0.367326
0.942231
0.260870
ENSG00000254093
PINX1
HNSC
Del
3.234269
0.079021
0.420873
0.534483
ENSG00000254093
PINX1
LIHC
Del
3.043841
0.099194
0.715089
0.678378
ENSG00000254093
PINX1
BLCA
Del
4.557972
0.129228
0.518729
0.588235
ENSG00000254093
PINX1
BRCA
Del
16.991309
0.139241
0.596803
0.518519
ENSG00000254093
PINX1
STAD
Amp
8.146706
0.297053
0.751116
0.383220
ENSG00000254093
PINX1
PRAD
Del
8.122387
0.137312
0.564040
0.502033
ENSG00000254093
PINX1
UCEC
Del
5.259009
0.090388
0.674370
0.215213
ENSG00000254093
PINX1
OV
Del
25.578826
0.421093
0.752424
0.694301
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