Ensembl ID ENSG00000247626 Gene ID 92935 Accession 25133
Gene Symbol MARS2 Alias MetRS;COXPD25;mtMetRS Full Name methionyl-tRNA synthetase 2, mitochondrial
Position 2 : 197705369 - 197708395 Length 3027 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]

ENSG00000247626 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000247626 MARS2 0.64 2.63e-15 COAD
ENSG00000247626 MARS2 1.12 8.88e-26 LUSC
ENSG00000247626 MARS2 0.86 3.84e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000247626 MARS2 STAD 0.021 low
ENSG00000247626 MARS2 UCEC 0.00047 low
ENSG00000247626 MARS2 THCA 0.00034 high
ENSG00000247626 MARS2 ACC 0.021 high
ENSG00000247626 MARS2 LGG 0.00012 high
ENSG00000247626 MARS2 LUSC 0.0036 low
ENSG00000247626 MARS2 HNSC 0.028 low
ENSG00000247626 MARS2 READ 0.023 low
ENSG00000247626 MARS2 COAD 0.02 low
ENSG00000247626 MARS2 UCS 0.028 high
ENSG00000247626 MARS2 KIRC 0.00026 low
ENSG00000247626 MARS2 PRAD 0.00034 low
ENSG00000247626 MARS2 BLCA 0.016 low
ENSG00000247626 MARS2 LAML 0.045 high
ENSG00000247626 MARS2 GBM 0.0037 low
ENSG00000247626 MARS2 SKCM 0.00028 high
ENSG00000247626 MARS2 CESC 0.0099 high
ENSG00000247626 MARS2 LIHC 0.018 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000247626 MARS2 CESC Amp 1.113137 0.145273 0.534423 0.162712
ENSG00000247626 MARS2 KIRP Amp 1.434009 0.083902 0.685829 0.177083
ENSG00000247626 MARS2 HNSC Amp 1.173903 0.128597 0.501473 0.159004
ENSG00000247626 MARS2 HNSC Del 0.767803 0.054962 0.298757 0.153257
ENSG00000247626 MARS2 BLCA Del 0.672221 0.075892 0.356796 0.318627