Ensembl ID ENSG00000244038 Gene ID 1650 Accession 2728
Gene Symbol DDOST Alias OST;WBP1;AGER1;CDG1R;GATD6;OST48;OKSWcl45 Full Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Position 1 : 20651767 - 20661544 Length 9778 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]

ENSG00000244038 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000244038 DDOST 0.45 8.80e-16 KIRC
ENSG00000244038 DDOST 0.83 3.93e-12 BLCA
ENSG00000244038 DDOST 0.48 1.47e-22 BRCA
ENSG00000244038 DDOST 0.62 1.27e-18 LUSC
ENSG00000244038 DDOST 0.48 8.90e-11 LIHC
ENSG00000244038 DDOST 0.92 4.41e-22 UCEC
ENSG00000244038 DDOST 0.71 2.33e-21 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000244038 DDOST pancreatic tumor 24471499
ENSG00000244038 DDOST cancer 31867042
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000244038 DDOST MESO 0.015 low
ENSG00000244038 DDOST SARC 0.0016 high
ENSG00000244038 DDOST CHOL 0.029 high
ENSG00000244038 DDOST UVM 0.032 low
ENSG00000244038 DDOST PAAD 0.029 high
ENSG00000244038 DDOST UCEC 0.00031 low
ENSG00000244038 DDOST THCA 0.018 high
ENSG00000244038 DDOST ACC 0.027 high
ENSG00000244038 DDOST LUSC 0.04 high
ENSG00000244038 DDOST HNSC 0.00044 high
ENSG00000244038 DDOST KICH 0.00011 high
ENSG00000244038 DDOST PCPG 0.0076 low
ENSG00000244038 DDOST BRCA 0.014 low
ENSG00000244038 DDOST COAD 0.013 low
ENSG00000244038 DDOST UCS 0.0088 high
ENSG00000244038 DDOST OV 0.023 low
ENSG00000244038 DDOST DLBC 0.025 low
ENSG00000244038 DDOST KIRC 0.0015 high
ENSG00000244038 DDOST LAML 0.01 low
ENSG00000244038 DDOST GBM 0.017 high
ENSG00000244038 DDOST SKCM 0.044 low
ENSG00000244038 DDOST CESC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000244038 DDOST CHOL Del 21.929463 1.103702 0.699731 0.805556
ENSG00000244038 DDOST LUSC Del 5.160097 0.114748 0.385237 0.455090
ENSG00000244038 DDOST LUAD Del 1.170597 0.057909 0.294699 0.238372
ENSG00000244038 DDOST CESC Del 1.420147 0.081474 0.419167 0.118644
ENSG00000244038 DDOST KIRP Del 6.528625 0.077064 0.585567 0.180556
ENSG00000244038 DDOST READ Del 8.741826 0.215874 0.450436 0.454545
ENSG00000244038 DDOST COAD Del 17.848803 0.155796 0.454534 0.354767
ENSG00000244038 DDOST UCS Del 1.146478 0.241663 0.480396 0.303571
ENSG00000244038 DDOST SARC Del 0.914968 0.128064 0.630285 0.163424
ENSG00000244038 DDOST GBM Del 4.073585 0.085374 0.521355 0.091854
ENSG00000244038 DDOST PAAD Del 2.918902 0.085318 0.352488 0.326087
ENSG00000244038 DDOST SKCM Del 2.062924 0.087615 0.449773 0.193460
ENSG00000244038 DDOST HNSC Del 2.521111 0.073214 0.378482 0.172414
ENSG00000244038 DDOST LIHC Del 16.358713 0.211848 0.540243 0.381081
ENSG00000244038 DDOST PCPG Del 2.584689 0.095567 0.676520 0.629630
ENSG00000244038 DDOST TGCT Del 0.602670 0.052689 0.351125 0.193333
ENSG00000244038 DDOST BLCA Del 0.718341 0.076953 0.315690 0.191176
ENSG00000244038 DDOST BRCA Del 36.941695 0.195178 0.433109 0.412037
ENSG00000244038 DDOST STAD Del 4.527323 0.104337 0.353898 0.251701
ENSG00000244038 DDOST UCEC Del 11.404583 0.127950 0.510681 0.146568
ENSG00000244038 DDOST MESO Del 4.157699 0.243907 0.533620 0.333333
ENSG00000244038 DDOST KIRC Del 7.234665 0.055978 0.419755 0.185606
ENSG00000244038 DDOST UVM Del 2.302714 0.116385 0.824497 0.312500
ENSG00000244038 DDOST OV Del 27.659321 0.435117 0.559538 0.431779