Ensembl ID ENSG00000239672 Gene ID 4830 Accession 7849
Gene Symbol NME1 Alias NB;AWD;NBS;GAAD;NDKA;NM23;NDPKA;NDPK-A;NM23-H1 Full Name NME/NM23 nucleoside diphosphate kinase 1
Position 17 : 51153559 - 51162428 Length 8870 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

ENSG00000239672 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000239672 NME1 0.83 3.05e-15 KIRC
ENSG00000239672 NME1 1.30 5.04e-15 BLCA
ENSG00000239672 NME1 1.93 3.05e-86 BRCA
ENSG00000239672 NME1 1.70 1.62e-48 COAD
ENSG00000239672 NME1 1.60 3.91e-11 READ
ENSG00000239672 NME1 2.20 1.54e-88 LUSC
ENSG00000239672 NME1 0.99 1.19e-21 PRAD
ENSG00000239672 NME1 1.90 6.76e-35 KIRP
ENSG00000239672 NME1 1.18 2.86e-17 LIHC
ENSG00000239672 NME1 1.10 3.99e-12 STAD
ENSG00000239672 NME1 1.79 4.01e-41 UCEC
ENSG00000239672 NME1 2.19 2.59e-73 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000239672 NME1 cancer 10428867
ENSG00000239672 NME1 tumor 10600306
ENSG00000239672 NME1 tumor 10611312
ENSG00000239672 NME1 breast cancer 10619258
ENSG00000239672 NME1 ovarian tumors 10723138
ENSG00000239672 NME1 tumors 10999750
ENSG00000239672 NME1 pancreatic tumors 11032947
ENSG00000239672 NME1 breast cancer 11063804
ENSG00000239672 NME1 breast cancers 11091753
ENSG00000239672 NME1 tumors 11115597
ENSG00000239672 NME1 tumor 11121025
ENSG00000239672 NME1 colorectal cancers 11223826
ENSG00000239672 NME1 tumors 11268486
ENSG00000239672 NME1 hematological cancers 11299850
ENSG00000239672 NME1 tumor 11367729
ENSG00000239672 NME1 ovarian cancer 11389062
ENSG00000239672 NME1 larynx cancer 11445859
ENSG00000239672 NME1 tumor 12007505
ENSG00000239672 NME1 hematological cancers 12050732
ENSG00000239672 NME1 colorectal tumors 12063967
ENSG00000239672 NME1 pancreatic cancer 12085237
ENSG00000239672 NME1 tumor 12109225
ENSG00000239672 NME1 tumor 12405283
ENSG00000239672 NME1 colorectal cancer 12474051
ENSG00000239672 NME1 tumor 12490715
ENSG00000239672 NME1 tumor 12628178
ENSG00000239672 NME1 Tumor 12628186
ENSG00000239672 NME1 colorectal cancer 12678475
ENSG00000239672 NME1 cancer 12848339
ENSG00000239672 NME1 AML 12848346
ENSG00000239672 NME1 tumor 12874011
ENSG00000239672 NME1 tumour 12922171
ENSG00000239672 NME1 tumors 1320361
ENSG00000239672 NME1 cervical cancer 1330098
ENSG00000239672 NME1 tumor 1377015
ENSG00000239672 NME1 Cancer 14601090
ENSG00000239672 NME1 metastatic colorectal cancer 14625187
ENSG00000239672 NME1 tumors 14691637
ENSG00000239672 NME1 tumor 14697505
ENSG00000239672 NME1 tumor 14960567
ENSG00000239672 NME1 tumours 14973550
ENSG00000239672 NME1 ovarian tumor 14981979
ENSG00000239672 NME1 cancer 15079086
ENSG00000239672 NME1 tumour 15083191
ENSG00000239672 NME1 metastatic tumors 15105900
ENSG00000239672 NME1 colorectal cancer 15138555
ENSG00000239672 NME1 tumors 15280446
ENSG00000239672 NME1 breast cancer 1537618
ENSG00000239672 NME1 ovarian cancers 15477760
ENSG00000239672 NME1 tumor 15485929
ENSG00000239672 NME1 ovarian cancer 15674352
ENSG00000239672 NME1 tumor 1568230
ENSG00000239672 NME1 tumor 15814641
ENSG00000239672 NME1 tumors 15928304
ENSG00000239672 NME1 cancer 15967806
ENSG00000239672 NME1 ovarian tumor 16044917
ENSG00000239672 NME1 colorectal cancer 16166432
ENSG00000239672 NME1 breast cancer 16317582
ENSG00000239672 NME1 anaplastic cancer 16350729
ENSG00000239672 NME1 cancer 16440314
ENSG00000239672 NME1 tumor 16442775
ENSG00000239672 NME1 Tumor 16459650
ENSG00000239672 NME1 tumors 16528541
ENSG00000239672 NME1 ovarian tumor 16635329
ENSG00000239672 NME1 ovarian tumors 16674097
ENSG00000239672 NME1 tumors 16814409
ENSG00000239672 NME1 tumors 16823850
ENSG00000239672 NME1 tumor 16862176
ENSG00000239672 NME1 cancer 16944300
ENSG00000239672 NME1 tumor 16944304
ENSG00000239672 NME1 cancer 17033939
ENSG00000239672 NME1 tumor 17057884
ENSG00000239672 NME1 tumour 17146477
ENSG00000239672 NME1 tumor 17241778
ENSG00000239672 NME1 tumor 17314099
ENSG00000239672 NME1 tumor 17390007
ENSG00000239672 NME1 non-small cell lung cancer 17688968
ENSG00000239672 NME1 tumor 17696918
ENSG00000239672 NME1 tumor 17708612
ENSG00000239672 NME1 tumor 17916563
ENSG00000239672 NME1 tumor 17936523
ENSG00000239672 NME1 breast cancer 17975005
ENSG00000239672 NME1 tumor 18154714
ENSG00000239672 NME1 tumour 18219290
ENSG00000239672 NME1 gastric cancer 18239814
ENSG00000239672 NME1 breast cancer 18446242
ENSG00000239672 NME1 tumour 18496563
ENSG00000239672 NME1 tumor 18498268
ENSG00000239672 NME1 breast cancer 18676749
ENSG00000239672 NME1 tumor 18686102
ENSG00000239672 NME1 tumor 18833326
ENSG00000239672 NME1 tumor 19022560
ENSG00000239672 NME1 tumor 19096443
ENSG00000239672 NME1 cancer 19170058
ENSG00000239672 NME1 breast cancer 19183483
ENSG00000239672 NME1 breast cancer 19266025
ENSG00000239672 NME1 lung cancer 19331130
ENSG00000239672 NME1 tumor 19377884
ENSG00000239672 NME1 cancer 19381784
ENSG00000239672 NME1 cancer 19421718
ENSG00000239672 NME1 tumors 19513384
ENSG00000239672 NME1 AML 19655221
ENSG00000239672 NME1 tumor 19796404
ENSG00000239672 NME1 breast cancer 20064251
ENSG00000239672 NME1 tumor 20145075
ENSG00000239672 NME1 tumor 20209495
ENSG00000239672 NME1 tumor 20401329
ENSG00000239672 NME1 tumor 20560137
ENSG00000239672 NME1 esophageal cancers 20570897
ENSG00000239672 NME1 tumor 20671611
ENSG00000239672 NME1 breast cancer 20723247
ENSG00000239672 NME1 cancer 20841469
ENSG00000239672 NME1 tumor 20878062
ENSG00000239672 NME1 cancer 20944141
ENSG00000239672 NME1 lung cancer 21106156
ENSG00000239672 NME1 tumours 21136925
ENSG00000239672 NME1 tumor 21225146
ENSG00000239672 NME1 lung cancer 21265090
ENSG00000239672 NME1 tumor 21279956
ENSG00000239672 NME1 tumors 21385632
ENSG00000239672 NME1 prostate cancer 21553004
ENSG00000239672 NME1 cancer 21562815
ENSG00000239672 NME1 tumor 21738525
ENSG00000239672 NME1 tumor 21738817
ENSG00000239672 NME1 breast cancer 21913743
ENSG00000239672 NME1 tumor 21941554
ENSG00000239672 NME1 tumor 21966347
ENSG00000239672 NME1 tumor 21987726
ENSG00000239672 NME1 tumor 22080566
ENSG00000239672 NME1 tumor 22087286
ENSG00000239672 NME1 Breast Cancer 22091350
ENSG00000239672 NME1 tumor 22192927
ENSG00000239672 NME1 breast cancer 22290468
ENSG00000239672 NME1 AML 22421058
ENSG00000239672 NME1 tumor 22429909
ENSG00000239672 NME1 tumor 22632416
ENSG00000239672 NME1 tumors 22662276
ENSG00000239672 NME1 breast cancer 22691413
ENSG00000239672 NME1 tumor 22699362
ENSG00000239672 NME1 breast cancer 2274350
ENSG00000239672 NME1 tumors 22892044
ENSG00000239672 NME1 gastric cancer 22903495
ENSG00000239672 NME1 tumor 23505541
ENSG00000239672 NME1 lung cancer 23599685
ENSG00000239672 NME1 tumor 23717685
ENSG00000239672 NME1 tumour 23725501
ENSG00000239672 NME1 tumor 23729363
ENSG00000239672 NME1 tumor 23856325
ENSG00000239672 NME1 cancer 24096484
ENSG00000239672 NME1 tumor 24133580
ENSG00000239672 NME1 tumor 2460224
ENSG00000239672 NME1 tumor 24622613
ENSG00000239672 NME1 cancer 24811176
ENSG00000239672 NME1 cancer 24829611
ENSG00000239672 NME1 tumor 25017017
ENSG00000239672 NME1 breast cancer 25048347
ENSG00000239672 NME1 breast cancer 25075023
ENSG00000239672 NME1 ovarian cancer 25141992
ENSG00000239672 NME1 tumor 25193865
ENSG00000239672 NME1 tumor 25234227
ENSG00000239672 NME1 tumor 25277180
ENSG00000239672 NME1 prostate cancer 25373728
ENSG00000239672 NME1 tumors 25428551
ENSG00000239672 NME1 breast cancer 25454514
ENSG00000239672 NME1 cancer 25700270
ENSG00000239672 NME1 tumor 25808322
ENSG00000239672 NME1 liver cancer 25872475
ENSG00000239672 NME1 tumor 26045708
ENSG00000239672 NME1 cancers 26074449
ENSG00000239672 NME1 tumour 26117539
ENSG00000239672 NME1 tumor 26119944
ENSG00000239672 NME1 tumour 26269723
ENSG00000239672 NME1 tumor 26314522
ENSG00000239672 NME1 breast cancer 26413311
ENSG00000239672 NME1 cancer 26486520
ENSG00000239672 NME1 tumor 26634527
ENSG00000239672 NME1 tumor 26825905
ENSG00000239672 NME1 ovarian cancer 26893013
ENSG00000239672 NME1 cancer 27094059
ENSG00000239672 NME1 tumours 27222072
ENSG00000239672 NME1 Breast Cancer 27509166
ENSG00000239672 NME1 tumor 27518571
ENSG00000239672 NME1 tumor 27698698
ENSG00000239672 NME1 thyroid cancers 27811013
ENSG00000239672 NME1 cancer 27840927
ENSG00000239672 NME1 colorectal cancer 28101224
ENSG00000239672 NME1 cancer 28128954
ENSG00000239672 NME1 breast cancer 28161101
ENSG00000239672 NME1 metastatic cancer 28216015
ENSG00000239672 NME1 colorectal cancer 28224416
ENSG00000239672 NME1 cancer 28331561
ENSG00000239672 NME1 Gastric Cancer 28401162
ENSG00000239672 NME1 tumor 28788083
ENSG00000239672 NME1 cancer 28920944
ENSG00000239672 NME1 cancer 28962550
ENSG00000239672 NME1 tumor 29035383
ENSG00000239672 NME1 cancer 29058704
ENSG00000239672 NME1 cancers 29058705
ENSG00000239672 NME1 tumor 29058706
ENSG00000239672 NME1 cancer 29062040
ENSG00000239672 NME1 tumor 29078900
ENSG00000239672 NME1 breast cancer 29203642
ENSG00000239672 NME1 tumour 29203880
ENSG00000239672 NME1 ovarian cancer 29274004
ENSG00000239672 NME1 breast cancer 29407582
ENSG00000239672 NME1 tumor 29441724
ENSG00000239672 NME1 tumour 29490009
ENSG00000239672 NME1 tumors 29507682
ENSG00000239672 NME1 tumors 29522283
ENSG00000239672 NME1 cancer 29525404
ENSG00000239672 NME1 breast cancer 29535799
ENSG00000239672 NME1 lung cancer 29541242
ENSG00000239672 NME1 tumours 29562234
ENSG00000239672 NME1 tumor 29589313
ENSG00000239672 NME1 tumor 29700912
ENSG00000239672 NME1 tumor 29956840
ENSG00000239672 NME1 tumor 29963765
ENSG00000239672 NME1 AML 30041457
ENSG00000239672 NME1 tumor 30158514
ENSG00000239672 NME1 tumor 30195750
ENSG00000239672 NME1 gastric cancer 30249868
ENSG00000239672 NME1 cancer 30396920
ENSG00000239672 NME1 lung cancer 30504895
ENSG00000239672 NME1 cancer 30584338
ENSG00000239672 NME1 tumor 30651219
ENSG00000239672 NME1 tumor 30662464
ENSG00000239672 NME1 tumor 30675295
ENSG00000239672 NME1 tumor 30678288
ENSG00000239672 NME1 cancer 30827726
ENSG00000239672 NME1 tumor 30875636
ENSG00000239672 NME1 Tumor 31123173
ENSG00000239672 NME1 breast cancer 31281727
ENSG00000239672 NME1 Tumor 31311812
ENSG00000239672 NME1 tumors 31312613
ENSG00000239672 NME1 tumor 31394634
ENSG00000239672 NME1 tumor 31427986
ENSG00000239672 NME1 tumour 31462745
ENSG00000239672 NME1 breast cancer 31598678
ENSG00000239672 NME1 tumor 31611991
ENSG00000239672 NME1 gastric cancer 31694930
ENSG00000239672 NME1 tumor 31734851
ENSG00000239672 NME1 tumor 31966710
ENSG00000239672 NME1 tumor 3346912
ENSG00000239672 NME1 colorectal cancer 7537507
ENSG00000239672 NME1 thyroid cancer 7617649
ENSG00000239672 NME1 epithelial ovarian cancer 7622307
ENSG00000239672 NME1 tumours 7658474
ENSG00000239672 NME1 tumors 7685630
ENSG00000239672 NME1 tumours 7734302
ENSG00000239672 NME1 skin tumor 7794272
ENSG00000239672 NME1 tumor 7896455
ENSG00000239672 NME1 tumors 7912561
ENSG00000239672 NME1 tumours 7919963
ENSG00000239672 NME1 colorectal cancer 7947085
ENSG00000239672 NME1 mammary cancers 7954474
ENSG00000239672 NME1 breast tumors 8028038
ENSG00000239672 NME1 tumors 8174043
ENSG00000239672 NME1 ovarian cancer 8242614
ENSG00000239672 NME1 colorectal cancer 8297127
ENSG00000239672 NME1 tumours 8390799
ENSG00000239672 NME1 tumor 8406509
ENSG00000239672 NME1 colorectal cancer 8631033
ENSG00000239672 NME1 breast cancer 8640802
ENSG00000239672 NME1 tumor 8641619
ENSG00000239672 NME1 tumor 8648172
ENSG00000239672 NME1 Ovarian Cancer 8651607
ENSG00000239672 NME1 cancers 8679442
ENSG00000239672 NME1 tumor 8692914
ENSG00000239672 NME1 tumour 8724537
ENSG00000239672 NME1 tumour 8932344
ENSG00000239672 NME1 tumor 8978595
ENSG00000239672 NME1 tumor 8984006
ENSG00000239672 NME1 tumor 9036878
ENSG00000239672 NME1 lung cancer 9066685
ENSG00000239672 NME1 tumor 9109790
ENSG00000239672 NME1 tumour 9167178
ENSG00000239672 NME1 tumor 9408751
ENSG00000239672 NME1 colorectal cancer 9538187
ENSG00000239672 NME1 tumors 9555115
ENSG00000239672 NME1 tumour 9569056
ENSG00000239672 NME1 renal tumors 9615786
ENSG00000239672 NME1 tumors 9816065
ENSG00000239672 NME1 Tumor 9874452
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000239672 NME1 SARC 0.001 high
ENSG00000239672 NME1 CHOL 0.015 high
ENSG00000239672 NME1 PAAD 0.026 high
ENSG00000239672 NME1 ACC 0.0013 high
ENSG00000239672 NME1 LGG 0.0045 high
ENSG00000239672 NME1 HNSC 0.0022 high
ENSG00000239672 NME1 READ 0.016 high
ENSG00000239672 NME1 LUAD 0.019 high
ENSG00000239672 NME1 PCPG 0.022 high
ENSG00000239672 NME1 THYM 0.0067 low
ENSG00000239672 NME1 COAD 0.013 low
ENSG00000239672 NME1 ESCA 0.024 low
ENSG00000239672 NME1 OV 0.0017 low
ENSG00000239672 NME1 BLCA 0.0067 low
ENSG00000239672 NME1 LAML 0.017 high
ENSG00000239672 NME1 SKCM 0.0019 high
ENSG00000239672 NME1 CESC 0.021 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000239672 NME1 SKCM Amp 2.469309 0.174782 0.534072 0.294278
ENSG00000239672 NME1 BRCA Amp 37.701683 0.472337 0.917255 0.321296