Ensembl ID ENSG00000221914 Gene ID 5520 Accession 9304
Gene Symbol PPP2R2A Alias B55A;PR52A;PR55A;B55ALPHA;PR55alpha Full Name protein phosphatase 2 regulatory subunit Balpha
Position 8 : 26291508 - 26372680 Length 81173 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

ENSG00000221914 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000221914 -0.8 9.31e-20 HNSC
ENSG00000221914 -0.8 1.09e-18 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000221914 tumors 16790090
ENSG00000221914 breast cancer 19890961
ENSG00000221914 tumor 20103675
ENSG00000221914 tumor 20237410
ENSG00000221914 prostate cancer 21872824
ENSG00000221914 lung cancer 21890451
ENSG00000221914 cancer 22522925
ENSG00000221914 tumor 22689922
ENSG00000221914 tumor 23044976
ENSG00000221914 tumor 23087057
ENSG00000221914 breast cancer 23905624
ENSG00000221914 non-small cell lung cancer 23959478
ENSG00000221914 lung cancer 24204789
ENSG00000221914 colorectal cancer 24448818
ENSG00000221914 AML 24858343
ENSG00000221914 tumor 25879784
ENSG00000221914 colorectal cancer 26054685
ENSG00000221914 tumor 26260902
ENSG00000221914 prostate cancer 26297546
ENSG00000221914 bladder cancer 26800397
ENSG00000221914 pancreatic cancer 26848620
ENSG00000221914 pancreatic cancer 26893480
ENSG00000221914 tumor 27531894
ENSG00000221914 lung cancer 27602961
ENSG00000221914 DLBCL 27720936
ENSG00000221914 cancer 27876019
ENSG00000221914 tumor 28783765
ENSG00000221914 breast cancer 29229993
ENSG00000221914 tumor 29435111
ENSG00000221914 ovarian cancer 29532877
ENSG00000221914 AML 29545342
ENSG00000221914 Bladder Cancer 29703843
ENSG00000221914 thyroid cancer 29882471
ENSG00000221914 breast cancer 29943541
ENSG00000221914 tumor 31221814
ENSG00000221914 AML 31496026
ENSG00000221914 prostate cancer 31822657
ENSG00000221914 cancer 31923339
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000221914 CHOL 0.029 high
ENSG00000221914 PAAD 0.021 high
ENSG00000221914 UCEC 0.016 high
ENSG00000221914 THCA 0.033 high
ENSG00000221914 ACC 0.018 high
ENSG00000221914 HNSC 0.021 low
ENSG00000221914 READ 0.015 low
ENSG00000221914 KIRP 0.00059 high
ENSG00000221914 PCPG 0.014 high
ENSG00000221914 COAD 0.0079 high
ENSG00000221914 UCS 0.041 high
ENSG00000221914 DLBC 0.021 high
ENSG00000221914 PRAD 0.025 high
ENSG00000221914 GBM 0.043 low
ENSG00000221914 CESC 0.044 low
ENSG00000221914 LIHC 0.00024 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000221914 LUSC Del 2.558304 0.089464 0.449747 0.656687
ENSG00000221914 LUAD Del 1.965021 0.066931 0.450486 0.513566
ENSG00000221914 READ Del 5.989707 0.168631 0.682412 0.587879
ENSG00000221914 COAD Del 7.451670 0.097222 0.674039 0.436807
ENSG00000221914 UCS Del 0.961999 0.224263 0.702658 0.553571
ENSG00000221914 ESCA Del 0.712627 0.097085 0.468503 0.461957
ENSG00000221914 LIHC Del 3.573701 0.105632 0.706626 0.702703
ENSG00000221914 BLCA Del 3.407042 0.116491 0.514896 0.602941
ENSG00000221914 BRCA Del 21.372876 0.152674 0.592079 0.536111
ENSG00000221914 STAD Del 1.417417 0.070949 0.441184 0.303855
ENSG00000221914 PRAD Del 24.776464 0.226432 0.573119 0.573171
ENSG00000221914 UCEC Del 9.262034 0.115496 0.697465 0.217069
ENSG00000221914 OV Del 36.773031 0.491400 0.767685 0.699482