Ensembl ID ENSG00000213639 Gene ID 5500 Accession 9282
Gene Symbol PPP1CB Alias MP;PP1B;PP1c;NSLH2;PP-1B;PPP1CD;PP1beta;PPP1beta;HEL-S-80p Full Name protein phosphatase 1 catalytic subunit beta
Position 2 : 28751640 - 28802940 Length 51301 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

ENSG00000213639 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000213639 PPP1CB -0.5 1.28e-12 HNSC
ENSG00000213639 PPP1CB -1.0 8.55e-18 BLCA
ENSG00000213639 PPP1CB -0.6 9.74e-14 COAD
ENSG00000213639 PPP1CB -0.9 1.22e-30 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000213639 PPP1CB tumors 19695104
ENSG00000213639 PPP1CB cancer 22537039
ENSG00000213639 PPP1CB tumors 22890320
ENSG00000213639 PPP1CB cancers 23382248
ENSG00000213639 PPP1CB cancer 28737169
ENSG00000213639 PPP1CB tumor 29285244
ENSG00000213639 PPP1CB Cancer 30158517
ENSG00000213639 PPP1CB tumor 30930989
ENSG00000213639 PPP1CB tumor 31554817
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000213639 PPP1CB PAAD 0.0012 high
ENSG00000213639 PPP1CB UCEC 0.044 high
ENSG00000213639 PPP1CB ACC 0.00041 high
ENSG00000213639 PPP1CB LUSC 0.0076 low
ENSG00000213639 PPP1CB HNSC 0.013 high
ENSG00000213639 PPP1CB KIRP 0.0017 high
ENSG00000213639 PPP1CB KICH 0.032 high
ENSG00000213639 PPP1CB PCPG 0.0014 high
ENSG00000213639 PPP1CB COAD 0.01 high
ENSG00000213639 PPP1CB OV 0.024 low
ENSG00000213639 PPP1CB DLBC 0.0092 high
ENSG00000213639 PPP1CB PRAD 0.046 low
ENSG00000213639 PPP1CB BLCA 0.0088 high
ENSG00000213639 PPP1CB SKCM 0.013 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000213639 PPP1CB TGCT Amp 1.710327 0.164688 0.447124 0.400000
ENSG00000213639 PPP1CB UCEC Amp 1.675438 0.126283 0.594652 0.230056
ENSG00000213639 PPP1CB OV Amp 1.031579 0.340807 0.664817 0.430052