Ensembl ID ENSG00000213639 Gene ID 5500 Accession 9282
Gene Symbol PPP1CB Alias MP;PP1B;PP1c;NSLH2;PP-1B;PPP1CD;PP1beta;PPP1beta;HEL-S-80p Full Name protein phosphatase 1 catalytic subunit beta
Position 2 : 28751640 - 28802940 Length 51301 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

ENSG00000213639 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000213639 -0.5 1.28e-12 HNSC
ENSG00000213639 -1.0 8.55e-18 BLCA
ENSG00000213639 -0.6 9.74e-14 COAD
ENSG00000213639 -0.9 1.22e-30 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000213639 tumors 19695104
ENSG00000213639 cancer 22537039
ENSG00000213639 tumors 22890320
ENSG00000213639 cancers 23382248
ENSG00000213639 cancer 28737169
ENSG00000213639 tumor 29285244
ENSG00000213639 Cancer 30158517
ENSG00000213639 tumor 30930989
ENSG00000213639 tumor 31554817
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000213639 PAAD 0.0012 high
ENSG00000213639 UCEC 0.044 high
ENSG00000213639 ACC 0.00041 high
ENSG00000213639 LUSC 0.0076 low
ENSG00000213639 HNSC 0.013 high
ENSG00000213639 KIRP 0.0017 high
ENSG00000213639 KICH 0.032 high
ENSG00000213639 PCPG 0.0014 high
ENSG00000213639 COAD 0.01 high
ENSG00000213639 OV 0.024 low
ENSG00000213639 DLBC 0.0092 high
ENSG00000213639 PRAD 0.046 low
ENSG00000213639 BLCA 0.0088 high
ENSG00000213639 SKCM 0.013 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000213639 TGCT Amp 1.710327 0.164688 0.447124 0.400000
ENSG00000213639 UCEC Amp 1.675438 0.126283 0.594652 0.230056
ENSG00000213639 OV Amp 1.031579 0.340807 0.664817 0.430052