Ensembl ID
ENSG00000213523
Gene ID
10011
Accession
11281
Gene Symbol
SRA1
Alias
SRA;SRAP;STRAA1;pp7684
Full Name
steroid receptor RNA activator 1
Position
5 : 140537340 - 140557473
Length
20134 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]
ENSG00000213523 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000213523
SRA1
0.53
2.06e-21
BRCA
ENSG00000213523
SRA1
0.87
1.75e-18
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000213523
SRA1
prostate cancer
12350225
ENSG00000213523
SRA1
prostate cancer
12473178
ENSG00000213523
SRA1
breast cancer
15147866
ENSG00000213523
SRA1
breast tumor
16152589
ENSG00000213523
SRA1
breast cancer
16848684
ENSG00000213523
SRA1
breast tumors
17710122
ENSG00000213523
SRA1
breast cancer
19483093
ENSG00000213523
SRA1
tumors
19740422
ENSG00000213523
SRA1
breast cancer
23579816
ENSG00000213523
SRA1
breast tumors
23907597
ENSG00000213523
SRA1
breast cancer
24486609
ENSG00000213523
SRA1
tumor
24704270
ENSG00000213523
SRA1
breast cancer
25874233
ENSG00000213523
SRA1
cancer
26581859
ENSG00000213523
SRA1
tumors
27694140
ENSG00000213523
SRA1
breast cancer
30238005
ENSG00000213523
SRA1
colon cancer
30545127
ENSG00000213523
SRA1
tumors
31507331
ENSG00000213523
SRA1
breast cancers
31945347
ENSG00000213523
SRA1
tumors
31975343
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000213523
SRA1
STAD
0.0089
high
show
ENSG00000213523
SRA1
PAAD
0.0069
low
show
ENSG00000213523
SRA1
ACC
0.015
high
show
ENSG00000213523
SRA1
LGG
0.00013
high
show
ENSG00000213523
SRA1
KIRP
0.0042
low
show
ENSG00000213523
SRA1
LUAD
0.04
high
show
ENSG00000213523
SRA1
THYM
0.02
high
show
ENSG00000213523
SRA1
COAD
0.027
low
show
ENSG00000213523
SRA1
UCS
0.046
high
show
ENSG00000213523
SRA1
TGCT
0.0033
low
show
ENSG00000213523
SRA1
GBM
0.0072
high
show
ENSG00000213523
SRA1
SKCM
0.035
low
show
ENSG00000213523
SRA1
CESC
0.0095
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000213523
SRA1
LAML
Del
6.887040
0.098062
0.800690
0.089005
ENSG00000213523
SRA1
LGG
Del
1.543113
0.048118
0.399767
0.089669
ENSG00000213523
SRA1
ACC
Amp
1.656823
0.409187
1.300433
0.677778
ENSG00000213523
SRA1
SKCM
Del
5.867539
0.131275
0.499850
0.343324
ENSG00000213523
SRA1
KIRC
Amp
51.061677
0.292110
0.543534
0.609848
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