Ensembl ID
ENSG00000205531
Gene ID
4676
Accession
7640
Gene Symbol
NAP1L4
Alias
NAP2;NAP2L;hNAP2;NAP1L4b
Full Name
nucleosome assembly protein 1 like 4
Position
11 : 2944431 - 2992377
Length
47947 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
ENSG00000205531 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000205531
0.36
2.69e-20
BRCA
ENSG00000205531
0.35
5.58e-13
COAD
ENSG00000205531
0.95
3.62e-23
KICH
ENSG00000205531
0.59
6.10e-20
LUSC
ENSG00000205531
0.50
1.37e-13
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000205531
liver tumor
18331625
ENSG00000205531
cancer
18765953
ENSG00000205531
lung cancer
19414677
ENSG00000205531
cancer
22500112
ENSG00000205531
lung cancer
22835075
ENSG00000205531
tumor
30591657
ENSG00000205531
Wilms tumor
9325046
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000205531
MESO
0.0015
high
show
ENSG00000205531
SARC
0.033
low
show
ENSG00000205531
UCEC
0.005
low
show
ENSG00000205531
ACC
0.00023
high
show
ENSG00000205531
LGG
0.00064
high
show
ENSG00000205531
HNSC
0.025
low
show
ENSG00000205531
READ
0.016
low
show
ENSG00000205531
PCPG
0.0066
low
show
ENSG00000205531
THYM
0.047
high
show
ENSG00000205531
COAD
0.019
high
show
ENSG00000205531
DLBC
0.0095
high
show
ENSG00000205531
SKCM
0.016
low
show
ENSG00000205531
CESC
0.0018
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000205531
LUSC
Del
12.289886
0.164883
0.375452
0.485030
ENSG00000205531
LUAD
Del
1.995215
0.067141
0.300146
0.265504
ENSG00000205531
LGG
Del
9.721440
0.102778
0.575321
0.202729
ENSG00000205531
CESC
Del
0.938690
0.071932
0.483656
0.352542
ENSG00000205531
SARC
Del
1.294836
0.139017
0.508814
0.392996
ENSG00000205531
GBM
Del
1.483583
0.061732
0.477153
0.213172
ENSG00000205531
PAAD
Del
1.487708
0.061193
0.341808
0.157609
ENSG00000205531
ESCA
Del
2.775091
0.152395
0.382809
0.429348
ENSG00000205531
HNSC
Del
2.369902
0.071762
0.365820
0.312261
ENSG00000205531
PCPG
Del
1.688309
0.078860
0.627179
0.358025
ENSG00000205531
BLCA
Del
2.590565
0.106408
0.435734
0.534314
ENSG00000205531
BRCA
Del
15.428316
0.134128
0.436646
0.282407
ENSG00000205531
STAD
Del
2.826732
0.087889
0.376938
0.224490
ENSG00000205531
UCEC
Del
4.044942
0.081349
0.531985
0.192950
ENSG00000205531
OV
Del
35.354815
0.482985
0.609857
0.595855
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