Ensembl ID ENSG00000204469 Gene ID 7916 Accession 13918
Gene Symbol PRRC2A Alias G2;BAT2;D6S51;D6S51E Full Name proline rich coiled-coil 2A
Position 6 : 31620715 - 31637771 Length 17057 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

ENSG00000204469 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000204469 PRRC2A 0.38 2.92e-18 BRCA
ENSG00000204469 PRRC2A 0.58 1.40e-12 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000204469 PRRC2A tumors 22328825
ENSG00000204469 PRRC2A breast cancer 23079975
ENSG00000204469 PRRC2A lung cancer 23221128
ENSG00000204469 PRRC2A Cancer 23861046
ENSG00000204469 PRRC2A lung tumors 25937444
ENSG00000204469 PRRC2A lung cancer 31069257
ENSG00000204469 PRRC2A cancer 31506425
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000204469 PRRC2A MESO 0.04 high
ENSG00000204469 PRRC2A SARC 0.00099 high
ENSG00000204469 PRRC2A STAD 0.015 low
ENSG00000204469 PRRC2A UVM 0.00065 low
ENSG00000204469 PRRC2A PAAD 0.0066 low
ENSG00000204469 PRRC2A UCEC 0.0028 high
ENSG00000204469 PRRC2A ACC 0.018 high
ENSG00000204469 PRRC2A READ 0.0083 low
ENSG00000204469 PRRC2A KICH 0.036 high
ENSG00000204469 PRRC2A BRCA 0.0064 high
ENSG00000204469 PRRC2A COAD 0.046 low
ENSG00000204469 PRRC2A UCS 0.029 high
ENSG00000204469 PRRC2A TGCT 0.043 low
ENSG00000204469 PRRC2A GBM 0.02 low
ENSG00000204469 PRRC2A SKCM 0.00014 high
ENSG00000204469 PRRC2A CESC 0.05 high
ENSG00000204469 PRRC2A LIHC 0.0044 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000204469 PRRC2A DLBC Del 1.473551 0.166909 0.534071 0.125000
ENSG00000204469 PRRC2A UVM Amp 1.976306 0.243776 1.147565 0.537500