Ensembl ID ENSG00000204394 Gene ID 7407 Accession 12651
Gene Symbol VARS1 Alias G7A;VARS;VARS2;NDMSCA Full Name valyl-tRNA synthetase 1
Position 6 : 31777518 - 31795752 Length 18235 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

ENSG00000204394 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000204394 VARS1 0.71 3.82e-33 BRCA
ENSG00000204394 VARS1 1.06 2.69e-27 COAD
ENSG00000204394 VARS1 0.86 5.06e-23 LUSC
ENSG00000204394 VARS1 0.62 7.69e-22 PRAD
ENSG00000204394 VARS1 0.76 3.92e-16 LIHC
ENSG00000204394 VARS1 1.12 1.14e-27 UCEC
ENSG00000204394 VARS1 1.17 2.20e-40 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000204394 VARS1 breast cancer 24510587
ENSG00000204394 VARS1 malignant tumor 30381327
ENSG00000204394 VARS1 cancer 30588513
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000204394 VARS1 MESO 0.011 high
ENSG00000204394 VARS1 PAAD 0.026 low
ENSG00000204394 VARS1 THCA 0.0059 high
ENSG00000204394 VARS1 ACC 0.049 high
ENSG00000204394 VARS1 LGG 0.0052 low
ENSG00000204394 VARS1 HNSC 0.039 high
ENSG00000204394 VARS1 READ 0.015 low
ENSG00000204394 VARS1 LUAD 0.00087 high
ENSG00000204394 VARS1 THYM 8e-04 low
ENSG00000204394 VARS1 BRCA 0.016 high
ENSG00000204394 VARS1 COAD 0.031 low
ENSG00000204394 VARS1 DLBC 0.043 low
ENSG00000204394 VARS1 KIRC 0.049 high
ENSG00000204394 VARS1 PRAD 0.05 high
ENSG00000204394 VARS1 LAML 0.0027 high
ENSG00000204394 VARS1 GBM 0.018 low
ENSG00000204394 VARS1 SKCM 0.0014 high
ENSG00000204394 VARS1 CESC 0.0016 high
ENSG00000204394 VARS1 LIHC 0.00041 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000204394 VARS1 DLBC Del 1.473551 0.166909 0.534071 0.125000
ENSG00000204394 VARS1 UVM Amp 1.976306 0.243776 1.147565 0.537500