Ensembl ID
ENSG00000204394
Gene ID
7407
Accession
12651
Gene Symbol
VARS1
Alias
G7A;VARS;VARS2;NDMSCA
Full Name
valyl-tRNA synthetase 1
Position
6 : 31777518 - 31795752
Length
18235 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
ENSG00000204394 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000204394
VARS1
0.71
3.82e-33
BRCA
ENSG00000204394
VARS1
1.06
2.69e-27
COAD
ENSG00000204394
VARS1
0.86
5.06e-23
LUSC
ENSG00000204394
VARS1
0.62
7.69e-22
PRAD
ENSG00000204394
VARS1
0.76
3.92e-16
LIHC
ENSG00000204394
VARS1
1.12
1.14e-27
UCEC
ENSG00000204394
VARS1
1.17
2.20e-40
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000204394
VARS1
breast cancer
24510587
ENSG00000204394
VARS1
malignant tumor
30381327
ENSG00000204394
VARS1
cancer
30588513
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000204394
VARS1
MESO
0.011
high
show
ENSG00000204394
VARS1
PAAD
0.026
low
show
ENSG00000204394
VARS1
THCA
0.0059
high
show
ENSG00000204394
VARS1
ACC
0.049
high
show
ENSG00000204394
VARS1
LGG
0.0052
low
show
ENSG00000204394
VARS1
HNSC
0.039
high
show
ENSG00000204394
VARS1
READ
0.015
low
show
ENSG00000204394
VARS1
LUAD
0.00087
high
show
ENSG00000204394
VARS1
THYM
8e-04
low
show
ENSG00000204394
VARS1
BRCA
0.016
high
show
ENSG00000204394
VARS1
COAD
0.031
low
show
ENSG00000204394
VARS1
DLBC
0.043
low
show
ENSG00000204394
VARS1
KIRC
0.049
high
show
ENSG00000204394
VARS1
PRAD
0.05
high
show
ENSG00000204394
VARS1
LAML
0.0027
high
show
ENSG00000204394
VARS1
GBM
0.018
low
show
ENSG00000204394
VARS1
SKCM
0.0014
high
show
ENSG00000204394
VARS1
CESC
0.0016
high
show
ENSG00000204394
VARS1
LIHC
0.00041
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000204394
VARS1
DLBC
Del
1.473551
0.166909
0.534071
0.125000
ENSG00000204394
VARS1
UVM
Amp
1.976306
0.243776
1.147565
0.537500
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