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Ensembl ID | ENSG00000204351 | Gene ID | 6499 | Accession | 10898 |
Gene Symbol | SKIC2 | Alias | HLP;170A;SKI2;DDX13;SKI2W;SKIV2;THES2;SKIV2L;SKIV2L1 | Full Name | SKI2 subunit of superkiller complex |
Position | 6 : 31959116 - 31969818 | Length | 10703 bases | Strand | Plus strand |
Status | Confidence | Main interacting RNAs | mRNA | RBP type | Canonical_RBPs |
Summary | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008] |
ENSG00000204351 Expression In 33 Tumors
Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
---|---|---|---|---|
ENSG00000204351 | SKIV2L | 0.53 | 3.25e-30 | BRCA |
ENSG00000204351 | SKIV2L | 0.58 | 9.65e-17 | LUSC |
ENSG00000204351 | SKIV2L | 0.35 | 2.01e-14 | PRAD |
ENSG00000204351 | SKIV2L | 0.61 | 3.51e-13 | UCEC |
ENSG00000204351 | SKIV2L | 0.77 | 9.38e-33 | LUAD |
Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
---|---|---|---|
ENSG00000204351 | SKIV2L | tumor | 15020404 |
Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
---|
Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
---|---|---|---|---|---|
ENSG00000204351 | SKIV2L | MESO | 0.047 | low | |
ENSG00000204351 | SKIV2L | SARC | 0.00011 | high | |
ENSG00000204351 | SKIV2L | UVM | 0.002 | high | |
ENSG00000204351 | SKIV2L | PAAD | 0.0068 | low | |
ENSG00000204351 | SKIV2L | UCEC | 0.02 | high | |
ENSG00000204351 | SKIV2L | THCA | 0.044 | high | |
ENSG00000204351 | SKIV2L | ACC | 0.0028 | high | |
ENSG00000204351 | SKIV2L | LGG | 0.014 | high | |
ENSG00000204351 | SKIV2L | READ | 0.015 | low | |
ENSG00000204351 | SKIV2L | KIRP | 0.00044 | high | |
ENSG00000204351 | SKIV2L | KICH | 0.00075 | high | |
ENSG00000204351 | SKIV2L | PCPG | 0.00048 | low | |
ENSG00000204351 | SKIV2L | COAD | 0.012 | high | |
ENSG00000204351 | SKIV2L | OV | 0.0068 | low | |
ENSG00000204351 | SKIV2L | DLBC | 0.036 | high | |
ENSG00000204351 | SKIV2L | PRAD | 0.01 | high | |
ENSG00000204351 | SKIV2L | GBM | 0.038 | high | |
ENSG00000204351 | SKIV2L | LIHC | 0.00085 | high |
Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
---|---|---|---|---|---|---|---|
ENSG00000204351 | SKIV2L | DLBC | Del | 1.473551 | 0.166909 | 0.534071 | 0.125000 |
ENSG00000204351 | SKIV2L | UVM | Amp | 1.976306 | 0.243776 | 1.147565 | 0.537500 |