Ensembl ID ENSG00000204351 Gene ID 6499 Accession 10898
Gene Symbol SKIC2 Alias HLP;170A;SKI2;DDX13;SKI2W;SKIV2;THES2;SKIV2L;SKIV2L1 Full Name SKI2 subunit of superkiller complex
Position 6 : 31959116 - 31969818 Length 10703 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

ENSG00000204351 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000204351 SKIV2L 0.53 3.25e-30 BRCA
ENSG00000204351 SKIV2L 0.58 9.65e-17 LUSC
ENSG00000204351 SKIV2L 0.35 2.01e-14 PRAD
ENSG00000204351 SKIV2L 0.61 3.51e-13 UCEC
ENSG00000204351 SKIV2L 0.77 9.38e-33 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000204351 SKIV2L tumor 15020404
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000204351 SKIV2L MESO 0.047 low
ENSG00000204351 SKIV2L SARC 0.00011 high
ENSG00000204351 SKIV2L UVM 0.002 high
ENSG00000204351 SKIV2L PAAD 0.0068 low
ENSG00000204351 SKIV2L UCEC 0.02 high
ENSG00000204351 SKIV2L THCA 0.044 high
ENSG00000204351 SKIV2L ACC 0.0028 high
ENSG00000204351 SKIV2L LGG 0.014 high
ENSG00000204351 SKIV2L READ 0.015 low
ENSG00000204351 SKIV2L KIRP 0.00044 high
ENSG00000204351 SKIV2L KICH 0.00075 high
ENSG00000204351 SKIV2L PCPG 0.00048 low
ENSG00000204351 SKIV2L COAD 0.012 high
ENSG00000204351 SKIV2L OV 0.0068 low
ENSG00000204351 SKIV2L DLBC 0.036 high
ENSG00000204351 SKIV2L PRAD 0.01 high
ENSG00000204351 SKIV2L GBM 0.038 high
ENSG00000204351 SKIV2L LIHC 0.00085 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000204351 SKIV2L DLBC Del 1.473551 0.166909 0.534071 0.125000
ENSG00000204351 SKIV2L UVM Amp 1.976306 0.243776 1.147565 0.537500