Ensembl ID ENSG00000204316 Gene ID 64978 Accession 14033
Gene Symbol MRPL38 Alias mL38;L38MT;RPML3;MRP-L3;HSPC262;MRP-L38 Full Name mitochondrial ribosomal protein L38
Position 17 : 75898644 - 75904884 Length 6241 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Non-canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

ENSG00000204316 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000204316 MRPL38 0.61 1.77e-15 BRCA
ENSG00000204316 MRPL38 0.90 9.21e-25 LUSC
ENSG00000204316 MRPL38 0.69 7.45e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000204316 MRPL38 liver cancer 31272500
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000204316 MRPL38 MESO 0.013 low
ENSG00000204316 MRPL38 STAD 0.008 low
ENSG00000204316 MRPL38 UVM 0.033 low
ENSG00000204316 MRPL38 PAAD 0.00031 low
ENSG00000204316 MRPL38 UCEC 0.0034 high
ENSG00000204316 MRPL38 ACC 0.0076 high
ENSG00000204316 MRPL38 HNSC 0.017 low
ENSG00000204316 MRPL38 KICH 0.035 high
ENSG00000204316 MRPL38 ESCA 0.015 low
ENSG00000204316 MRPL38 OV 0.033 low
ENSG00000204316 MRPL38 DLBC 0.029 low
ENSG00000204316 MRPL38 PRAD 0.028 high
ENSG00000204316 MRPL38 GBM 0.028 high
ENSG00000204316 MRPL38 CESC 8e-04 high
ENSG00000204316 MRPL38 LIHC 0.011 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000204316 MRPL38 LUSC Amp 2.793190 0.256554 0.458715 0.479042
ENSG00000204316 MRPL38 LUAD Amp 1.891125 0.147000 0.396133 0.490310
ENSG00000204316 MRPL38 LGG Amp 4.107918 0.089248 0.642367 0.083821
ENSG00000204316 MRPL38 CESC Amp 4.694463 0.255999 0.700018 0.250847
ENSG00000204316 MRPL38 UCS Amp 2.279497 0.730271 0.850807 0.553571
ENSG00000204316 MRPL38 PAAD Del 3.747687 0.098262 0.356137 0.228261
ENSG00000204316 MRPL38 SKCM Amp 5.611761 0.257398 0.561426 0.343324
ENSG00000204316 MRPL38 LIHC Amp 7.839590 0.255614 0.656325 0.386486
ENSG00000204316 MRPL38 BLCA Amp 1.952842 0.208119 0.463362 0.473039
ENSG00000204316 MRPL38 BRCA Amp 23.496974 0.375637 0.647559 0.375926
ENSG00000204316 MRPL38 PRAD Amp 0.751957 0.046451 0.524691 0.042683
ENSG00000204316 MRPL38 UCEC Amp 3.514385 0.159443 0.554422 0.176252
ENSG00000204316 MRPL38 OV Amp 1.151214 0.345293 0.545341 0.329879