Ensembl ID ENSG00000198945 Gene ID 84456 Accession 23035
Gene Symbol L3MBTL3 Alias MBT1;MBT-1 Full Name L3MBTL histone methyl-lysine binding protein 3
Position 6 : 130013699 - 130141449 Length 127751 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]

ENSG00000198945 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000198945 cancer 22145013
ENSG00000198945 malignant brain tumor 23292653
ENSG00000198945 tumour 23505385
ENSG00000198945 prostate cancer 27432226
ENSG00000198945 prostate cancer 28115406
ENSG00000198945 malignant brain tumor 29100496
ENSG00000198945 malignant-brain-tumor 30442713
ENSG00000198945 breast cancer 30988301
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000198945 MESO 0.022 low
ENSG00000198945 SARC 0.018 high
ENSG00000198945 STAD 0.0056 high
ENSG00000198945 PAAD 0.0029 high
ENSG00000198945 THCA 0.023 high
ENSG00000198945 ACC 0.025 high
ENSG00000198945 LUSC 0.0072 high
ENSG00000198945 HNSC 0.013 high
ENSG00000198945 KICH 0.023 high
ENSG00000198945 LUAD 0.0057 high
ENSG00000198945 UCS 0.016 low
ENSG00000198945 ESCA 0.021 low
ENSG00000198945 DLBC 0.036 high
ENSG00000198945 KIRC 0.01 low
ENSG00000198945 BLCA 0.019 low
ENSG00000198945 LAML 0.024 high
ENSG00000198945 GBM 0.0024 low
ENSG00000198945 SKCM 0.045 low
ENSG00000198945 LIHC 0.036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000198945 LUAD Del 0.618568 0.049936 0.377805 0.492248
ENSG00000198945 LGG Del 1.646146 0.049173 0.577001 0.153996
ENSG00000198945 GBM Del 5.327452 0.094943 0.556675 0.277296
ENSG00000198945 SKCM Del 4.162433 0.113280 0.562402 0.585831
ENSG00000198945 LIHC Del 1.808100 0.083101 0.590809 0.348649
ENSG00000198945 DLBC Del 1.157828 0.146609 0.576941 0.291667
ENSG00000198945 MESO Del 0.841360 0.129420 0.533565 0.448276
ENSG00000198945 KIRC Del 4.950082 0.046546 0.457214 0.280303
ENSG00000198945 OV Del 6.950258 0.269073 0.604163 0.588946