Ensembl ID ENSG00000198901 Gene ID 9055 Accession 9341
Gene Symbol PRC1 Alias ASE1 Full Name protein regulator of cytokinesis 1
Position 15 : 90966040 - 90995629 Length 29590 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

ENSG00000198901 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000198901 PRC1 1.34 2.42e-47 KIRC
ENSG00000198901 PRC1 1.12 1.11e-24 HNSC
ENSG00000198901 PRC1 1.48 8.21e-12 BLCA
ENSG00000198901 PRC1 2.64 2.62e-154 BRCA
ENSG00000198901 PRC1 1.18 1.22e-35 COAD
ENSG00000198901 PRC1 3.57 1.50e-249 LUSC
ENSG00000198901 PRC1 0.99 2.27e-16 PRAD
ENSG00000198901 PRC1 3.21 1.10e-80 LIHC
ENSG00000198901 PRC1 1.70 4.45e-28 STAD
ENSG00000198901 PRC1 2.48 1.62e-64 UCEC
ENSG00000198901 PRC1 1.87 8.59e-16 ESCA
ENSG00000198901 PRC1 3.95 3.04e-28 CHOL
ENSG00000198901 PRC1 3.87 6.27e-25 CESC
ENSG00000198901 PRC1 2.51 1.25e-73 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000198901 PRC1 cancer 16529553
ENSG00000198901 PRC1 cancer 16710298
ENSG00000198901 PRC1 prostate cancer 17134822
ENSG00000198901 PRC1 breast cancer 17233835
ENSG00000198901 PRC1 tumor 17374722
ENSG00000198901 PRC1 bladder cancer 17409436
ENSG00000198901 PRC1 GBM 17960622
ENSG00000198901 PRC1 breast cancer 18587273
ENSG00000198901 PRC1 cancer 19602592
ENSG00000198901 PRC1 tumor 19636380
ENSG00000198901 PRC1 cancer 19723660
ENSG00000198901 PRC1 tumor 19749759
ENSG00000198901 PRC1 cancer 19956605
ENSG00000198901 PRC1 cancer 20347825
ENSG00000198901 PRC1 tumor 20543829
ENSG00000198901 PRC1 tumour 20601937
ENSG00000198901 PRC1 gastric cancer 21060834
ENSG00000198901 PRC1 cancer 21195142
ENSG00000198901 PRC1 cancers 21881606
ENSG00000198901 PRC1 tumor 22096074
ENSG00000198901 PRC1 tumor 22766604
ENSG00000198901 PRC1 cancer 23256043
ENSG00000198901 PRC1 tumor 23357979
ENSG00000198901 PRC1 tumor 23405241
ENSG00000198901 PRC1 cancers 23437065
ENSG00000198901 PRC1 cancer 23648477
ENSG00000198901 PRC1 cancer 23902761
ENSG00000198901 PRC1 cancer 23942079
ENSG00000198901 PRC1 cancers 23982173
ENSG00000198901 PRC1 tumor 24069565
ENSG00000198901 PRC1 malignant brain tumour 24369422
ENSG00000198901 PRC1 tumour 24728135
ENSG00000198901 PRC1 breast cancer 24742605
ENSG00000198901 PRC1 cancer 24905164
ENSG00000198901 PRC1 AML 24953053
ENSG00000198901 PRC1 breast cancer 25038754
ENSG00000198901 PRC1 cancer 25071008
ENSG00000198901 PRC1 prostate cancer 25115397
ENSG00000198901 PRC1 breast cancer 25505268
ENSG00000198901 PRC1 cancer 25634095
ENSG00000198901 PRC1 breast tumors 26000042
ENSG00000198901 PRC1 cancer 26416703
ENSG00000198901 PRC1 tumor 26526724
ENSG00000198901 PRC1 tumours 26573325
ENSG00000198901 PRC1 cancers 26580594
ENSG00000198901 PRC1 biliary tract cancer 26623561
ENSG00000198901 PRC1 tumor 26693053
ENSG00000198901 PRC1 tumor 26716510
ENSG00000198901 PRC1 prostate cancer 26807715
ENSG00000198901 PRC1 tumors 26894859
ENSG00000198901 PRC1 prostate cancer 26898432
ENSG00000198901 PRC1 tumours 26941395
ENSG00000198901 PRC1 tumor 27007508
ENSG00000198901 PRC1 AML 27010239
ENSG00000198901 PRC1 breast cancer 27053251
ENSG00000198901 PRC1 cancer 27125204
ENSG00000198901 PRC1 cancer 27168727
ENSG00000198901 PRC1 GBM 27291091
ENSG00000198901 PRC1 tumor 27326334
ENSG00000198901 PRC1 tumors 27488310
ENSG00000198901 PRC1 cancer 27488323
ENSG00000198901 PRC1 Cancer 27505665
ENSG00000198901 PRC1 tumors 27505863
ENSG00000198901 PRC1 tumor 27510973
ENSG00000198901 PRC1 brain tumors 27568929
ENSG00000198901 PRC1 tumor 27643538
ENSG00000198901 PRC1 tumor 27730210
ENSG00000198901 PRC1 tumors of the thyroid 27796194
ENSG00000198901 PRC1 cancer 27827373
ENSG00000198901 PRC1 tumors 27863398
ENSG00000198901 PRC1 tumor 27864346
ENSG00000198901 PRC1 cancer 27893710
ENSG00000198901 PRC1 gastric cancer 27923621
ENSG00000198901 PRC1 GBM 28018136
ENSG00000198901 PRC1 tumor 28061449
ENSG00000198901 PRC1 tumour 28190297
ENSG00000198901 PRC1 Cancer 28329686
ENSG00000198901 PRC1 cancer 28382142
ENSG00000198901 PRC1 cancer 28429652
ENSG00000198901 PRC1 bladder cancer 28515962
ENSG00000198901 PRC1 tumor 28577303
ENSG00000198901 PRC1 cancers 28580277
ENSG00000198901 PRC1 Tumour 28587163
ENSG00000198901 PRC1 tumor 28646916
ENSG00000198901 PRC1 cervical cancer 28670392
ENSG00000198901 PRC1 AML 28718414
ENSG00000198901 PRC1 cancer 28776911
ENSG00000198901 PRC1 cancer 28840006
ENSG00000198901 PRC1 tumor 29050200
ENSG00000198901 PRC1 breast cancer 29085450
ENSG00000198901 PRC1 liver cancer 29097204
ENSG00000198901 PRC1 cervical cancer 29103025
ENSG00000198901 PRC1 mammary cancer 29115935
ENSG00000198901 PRC1 cancer 29187402
ENSG00000198901 PRC1 tumor 29229426
ENSG00000198901 PRC1 cancer 29337063
ENSG00000198901 PRC1 tumours 29357360
ENSG00000198901 PRC1 cancers 29379165
ENSG00000198901 PRC1 AML 29383137
ENSG00000198901 PRC1 cancer 29383875
ENSG00000198901 PRC1 cancer 29394261
ENSG00000198901 PRC1 prostate cancer 29402932
ENSG00000198901 PRC1 Cancer 29413422
ENSG00000198901 PRC1 gastric cancer 29422082
ENSG00000198901 PRC1 tumor 29435157
ENSG00000198901 PRC1 AML 29527516
ENSG00000198901 PRC1 tumor 29560857
ENSG00000198901 PRC1 HNSCC 29667751
ENSG00000198901 PRC1 cancer 29670361
ENSG00000198901 PRC1 cancers 29723807
ENSG00000198901 PRC1 tumor 29748662
ENSG00000198901 PRC1 tumors 29752448
ENSG00000198901 PRC1 prostate cancer 29862993
ENSG00000198901 PRC1 AML 29877252
ENSG00000198901 PRC1 cancers 29886801
ENSG00000198901 PRC1 cancer 29904729
ENSG00000198901 PRC1 cancer 30068546
ENSG00000198901 PRC1 cancer 30139998
ENSG00000198901 PRC1 tumor 30341152
ENSG00000198901 PRC1 tumor 30374364
ENSG00000198901 PRC1 cancer 30380541
ENSG00000198901 PRC1 cancer 30429953
ENSG00000198901 PRC1 cancer 30478317
ENSG00000198901 PRC1 tumor 30643969
ENSG00000198901 PRC1 tumor 30655550
ENSG00000198901 PRC1 breast cancer 30820027
ENSG00000198901 PRC1 cancer 30881920
ENSG00000198901 PRC1 cancers 30992249
ENSG00000198901 PRC1 tumor 30992425
ENSG00000198901 PRC1 liver cancer 31001331
ENSG00000198901 PRC1 ovarian cancer 31043753
ENSG00000198901 PRC1 cancer 31150156
ENSG00000198901 PRC1 tumors 31179414
ENSG00000198901 PRC1 TGCTs 31181810
ENSG00000198901 PRC1 tumor 31211140
ENSG00000198901 PRC1 cancers 31323431
ENSG00000198901 PRC1 prostate cancer 31327655
ENSG00000198901 PRC1 tumor 31333911
ENSG00000198901 PRC1 Cancer 31408617
ENSG00000198901 PRC1 breast cancer 31423162
ENSG00000198901 PRC1 tumor 31438464
ENSG00000198901 PRC1 cancer 31451683
ENSG00000198901 PRC1 tumor 31471323
ENSG00000198901 PRC1 tumor 31545466
ENSG00000198901 PRC1 tumor 31572440
ENSG00000198901 PRC1 tumor 31737106
ENSG00000198901 PRC1 lung cancer 31760859
ENSG00000198901 PRC1 cancer 31792072
ENSG00000198901 PRC1 tumor 31856871
ENSG00000198901 PRC1 ovarian cancer 31922238
ENSG00000198901 PRC1 acute myeloid leukemia (AML) 31940477
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000198901 PRC1 SARC 0.0026 high
ENSG00000198901 PRC1 STAD 0.029 low
ENSG00000198901 PRC1 CHOL 0.029 high
ENSG00000198901 PRC1 UCEC 0.0015 high
ENSG00000198901 PRC1 HNSC 0.028 high
ENSG00000198901 PRC1 READ 0.0041 low
ENSG00000198901 PRC1 PCPG 0.0054 high
ENSG00000198901 PRC1 THYM 0.003 low
ENSG00000198901 PRC1 OV 0.023 low
ENSG00000198901 PRC1 BLCA 0.025 high
ENSG00000198901 PRC1 LAML 0.043 high
ENSG00000198901 PRC1 GBM 0.033 high
ENSG00000198901 PRC1 SKCM 0.00018 high
ENSG00000198901 PRC1 LIHC 5e-04 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000198901 PRC1 LUSC Amp 0.932308 0.201825 0.429327 0.335329
ENSG00000198901 PRC1 CESC Amp 1.777701 0.171260 0.544559 0.257627
ENSG00000198901 PRC1 SKCM Amp 3.443595 0.201478 0.530339 0.326975
ENSG00000198901 PRC1 BRCA Amp 0.749421 0.146294 0.533419 0.164815
ENSG00000198901 PRC1 STAD Amp 5.231469 0.242094 0.557933 0.231293
ENSG00000198901 PRC1 OV Amp 1.099074 0.343334 0.669705 0.246978