Ensembl ID ENSG00000198874 Gene ID 55253 Accession 25598
Gene Symbol TYW1 Alias TYW1A;RSAFD1;YPL207W Full Name tRNA-yW synthesizing protein 1 homolog
Position 7 : 66996820 - 67239514 Length 242695 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

ENSG00000198874 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000198874 TYW1 0.23 2.99e-11 BRCA
ENSG00000198874 TYW1 0.77 3.68e-23 KICH
ENSG00000198874 TYW1 0.52 7.31e-11 STAD
ENSG00000198874 TYW1 0.38 2.96e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000198874 TYW1 tumor 31817495
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000198874 TYW1 MESO 0.0021 low
ENSG00000198874 TYW1 STAD 0.027 low
ENSG00000198874 TYW1 UVM 0.047 high
ENSG00000198874 TYW1 PAAD 0.039 low
ENSG00000198874 TYW1 UCEC 0.03 high
ENSG00000198874 TYW1 THCA 0.0089 high
ENSG00000198874 TYW1 LUSC 0.007 low
ENSG00000198874 TYW1 KICH 0.0098 high
ENSG00000198874 TYW1 COAD 0.032 high
ENSG00000198874 TYW1 UCS 0.016 low
ENSG00000198874 TYW1 OV 0.00031 high
ENSG00000198874 TYW1 KIRC 0.04 low
ENSG00000198874 TYW1 TGCT 0.036 high
ENSG00000198874 TYW1 BLCA 0.013 high
ENSG00000198874 TYW1 LAML 0.00079 low
ENSG00000198874 TYW1 GBM 0.0093 high
ENSG00000198874 TYW1 SKCM 0.00036 low
ENSG00000198874 TYW1 CESC 0.0084 high
ENSG00000198874 TYW1 LIHC 0.031 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000198874 TYW1 KIRP Amp 1.259300 0.072420 0.903267 0.611111
ENSG00000198874 TYW1 GBM Amp 1.168574 0.076660 0.790172 0.824957
ENSG00000198874 TYW1 TGCT Amp 0.658729 0.114169 0.534135 0.806667
ENSG00000198874 TYW1 STAD Amp 1.042485 0.142053 0.511289 0.435374