Ensembl ID
ENSG00000198874
Gene ID
55253
Accession
25598
Gene Symbol
TYW1
Alias
TYW1A;RSAFD1;YPL207W
Full Name
tRNA-yW synthesizing protein 1 homolog
Position
7 : 66996820 - 67239514
Length
242695 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
ENSG00000198874 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000198874
TYW1
0.23
2.99e-11
BRCA
ENSG00000198874
TYW1
0.77
3.68e-23
KICH
ENSG00000198874
TYW1
0.52
7.31e-11
STAD
ENSG00000198874
TYW1
0.38
2.96e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000198874
TYW1
tumor
31817495
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000198874
TYW1
MESO
0.0021
low
show
ENSG00000198874
TYW1
STAD
0.027
low
show
ENSG00000198874
TYW1
UVM
0.047
high
show
ENSG00000198874
TYW1
PAAD
0.039
low
show
ENSG00000198874
TYW1
UCEC
0.03
high
show
ENSG00000198874
TYW1
THCA
0.0089
high
show
ENSG00000198874
TYW1
LUSC
0.007
low
show
ENSG00000198874
TYW1
KICH
0.0098
high
show
ENSG00000198874
TYW1
COAD
0.032
high
show
ENSG00000198874
TYW1
UCS
0.016
low
show
ENSG00000198874
TYW1
OV
0.00031
high
show
ENSG00000198874
TYW1
KIRC
0.04
low
show
ENSG00000198874
TYW1
TGCT
0.036
high
show
ENSG00000198874
TYW1
BLCA
0.013
high
show
ENSG00000198874
TYW1
LAML
0.00079
low
show
ENSG00000198874
TYW1
GBM
0.0093
high
show
ENSG00000198874
TYW1
SKCM
0.00036
low
show
ENSG00000198874
TYW1
CESC
0.0084
high
show
ENSG00000198874
TYW1
LIHC
0.031
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000198874
TYW1
KIRP
Amp
1.259300
0.072420
0.903267
0.611111
ENSG00000198874
TYW1
GBM
Amp
1.168574
0.076660
0.790172
0.824957
ENSG00000198874
TYW1
TGCT
Amp
0.658729
0.114169
0.534135
0.806667
ENSG00000198874
TYW1
STAD
Amp
1.042485
0.142053
0.511289
0.435374
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