Ensembl ID ENSG00000198056 Gene ID 5557 Accession 9369
Gene Symbol PRIM1 Alias p49;PDIL Full Name DNA primase subunit 1
Position 12 : 56730438 - 56752374 Length 21937 bases Strand Minus strand
Status Confidence Main interacting RNAsdiverseRBP type Non-canonical_RBPs
Summary The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008]

ENSG00000198056 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000198056 PRIM1 0.58 3.86e-16 KIRC
ENSG00000198056 PRIM1 0.82 3.21e-14 HNSC
ENSG00000198056 PRIM1 0.69 5.44e-26 BRCA
ENSG00000198056 PRIM1 0.91 1.47e-18 COAD
ENSG00000198056 PRIM1 1.36 4.54e-37 LUSC
ENSG00000198056 PRIM1 1.27 2.57e-22 LIHC
ENSG00000198056 PRIM1 0.87 1.01e-11 STAD
ENSG00000198056 PRIM1 0.87 4.82e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000198056 PRIM1 cancers 10441007
ENSG00000198056 PRIM1 tumor 30097999
ENSG00000198056 PRIM1 Cancer 30257222
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000198056 PRIM1 SARC 0.044 high
ENSG00000198056 PRIM1 UCEC 0.0078 high
ENSG00000198056 PRIM1 HNSC 0.0078 low
ENSG00000198056 PRIM1 READ 0.004 low
ENSG00000198056 PRIM1 KIRP 0.00049 high
ENSG00000198056 PRIM1 LUAD 0.00088 high
ENSG00000198056 PRIM1 PCPG 0.021 high
ENSG00000198056 PRIM1 THYM 0.0012 low
ENSG00000198056 PRIM1 BRCA 0.0038 high
ENSG00000198056 PRIM1 UCS 0.05 low
ENSG00000198056 PRIM1 OV 0.0028 low
ENSG00000198056 PRIM1 KIRC 0.00011 low
ENSG00000198056 PRIM1 PRAD 0.034 low
ENSG00000198056 PRIM1 BLCA 0.037 high
ENSG00000198056 PRIM1 CESC 0.027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000198056 PRIM1 LUAD Amp 0.696237 0.116608 0.417173 0.304264
ENSG00000198056 PRIM1 ACC Amp 0.778019 0.257946 1.129237 0.755556
ENSG00000198056 PRIM1 SARC Amp 1.492405 0.304794 1.088471 0.163424
ENSG00000198056 PRIM1 GBM Amp 0.609153 0.064836 0.737505 0.097054
ENSG00000198056 PRIM1 PCPG Amp 0.805519 0.072315 0.622754 0.092593