Ensembl ID ENSG00000197837 Gene ID 121504 Accession 20510
Gene Symbol H4C16 Alias H4/p;H4C1;H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4-16;H4C11;H4C12;H4C13;H4C14;H4C15;HIST4H4 Full Name H4 histone 16
Position 12 : 14767999 - 14771131 Length 3133 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]

ENSG00000197837 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197837 1.44 3.04e-24 BRCA
ENSG00000197837 1.20 5.21e-19 LUSC
ENSG00000197837 1.16 2.49e-11 PRAD
ENSG00000197837 1.17 6.37e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197837 tumors 10344733
ENSG00000197837 tumour 10376979
ENSG00000197837 breast cancer 11682064
ENSG00000197837 Skin tumors 11782361
ENSG00000197837 tumor 12385581
ENSG00000197837 cancer 12579268
ENSG00000197837 gastric cancer 12677198
ENSG00000197837 tumor 12724227
ENSG00000197837 cancer 12865631
ENSG00000197837 Tumor 12891711
ENSG00000197837 tumor 12939461
ENSG00000197837 colon cancer 12975486
ENSG00000197837 tumours 14614037
ENSG00000197837 cancer 15095300
ENSG00000197837 cancer 15765097
ENSG00000197837 cancer 16131487
ENSG00000197837 tumors 16205112
ENSG00000197837 tumor 16254189
ENSG00000197837 tumors 16270534
ENSG00000197837 breast cancer 16322686
ENSG00000197837 cancer 16404435
ENSG00000197837 tumor 1644858
ENSG00000197837 tumor 16488987
ENSG00000197837 liver tumors 16497704
ENSG00000197837 cancer 16699174
ENSG00000197837 breast cancer 16707467
ENSG00000197837 breast cancer 16861913
ENSG00000197837 tumor 16863736
ENSG00000197837 tumor 1711413
ENSG00000197837 pediatric tumors 17725108
ENSG00000197837 cancer 17729398
ENSG00000197837 lung cancer 18172270
ENSG00000197837 prostate cancer 18187659
ENSG00000197837 tumour 18384290
ENSG00000197837 cancer 18595135
ENSG00000197837 cancers 18701507
ENSG00000197837 lung cancer 18974389
ENSG00000197837 cancer 19056850
ENSG00000197837 tumor 19086847
ENSG00000197837 DLBCL 19438744
ENSG00000197837 cancer 19509260
ENSG00000197837 pancreatic cancer 19582723
ENSG00000197837 cancer 19961487
ENSG00000197837 ovarian epithelial tumors 20057286
ENSG00000197837 ovarian cancer 20111712
ENSG00000197837 tumor 20534538
ENSG00000197837 cancer 21145737
ENSG00000197837 breast cancers 21321083
ENSG00000197837 ovarian cancer 21355783
ENSG00000197837 cancer 21415707
ENSG00000197837 AML 21968610
ENSG00000197837 cancer 22035019
ENSG00000197837 cancer 22260708
ENSG00000197837 tumor 22279574
ENSG00000197837 cancer 22419068
ENSG00000197837 tumours 22569052
ENSG00000197837 pancreatic cancer 22607671
ENSG00000197837 tumor 22720237
ENSG00000197837 tumor 23019525
ENSG00000197837 tumor 23308215
ENSG00000197837 prostate cancer 23524101
ENSG00000197837 tumor 23553687
ENSG00000197837 tumor 23720754
ENSG00000197837 cancer 23826629
ENSG00000197837 prostate cancer 24065480
ENSG00000197837 thyroid cancer 24155971
ENSG00000197837 lung cancer 24283195
ENSG00000197837 tumor 24778322
ENSG00000197837 cancer 24913909
ENSG00000197837 prostate cancer 24937452
ENSG00000197837 cancers 24953066
ENSG00000197837 tumor 25073158
ENSG00000197837 pancreatic cancer 25152840
ENSG00000197837 colon cancer 25451013
ENSG00000197837 non-small-cell lung cancer 25473433
ENSG00000197837 tumors 25512468
ENSG00000197837 cancers 25512710
ENSG00000197837 breast tumors 25814362
ENSG00000197837 tumour 25864732
ENSG00000197837 tumors 25889518
ENSG00000197837 tumor 25954275
ENSG00000197837 Endometrial Cancer 26222483
ENSG00000197837 cancers 26321891
ENSG00000197837 tumors 26929985
ENSG00000197837 lung cancer 27091080
ENSG00000197837 prostate cancer 27268279
ENSG00000197837 cancer 27322556
ENSG00000197837 cancer 27499010
ENSG00000197837 cancer 27994746
ENSG00000197837 cancer 28139737
ENSG00000197837 tumor 28360947
ENSG00000197837 Prostate Cancer 28609657
ENSG00000197837 tumors 28866885
ENSG00000197837 cancer 28874504
ENSG00000197837 lung cancer 29030587
ENSG00000197837 prostate cancer 29069764
ENSG00000197837 cervical cancer 29184082
ENSG00000197837 tumor 29250163
ENSG00000197837 tumor 29308302
ENSG00000197837 cancer 29401749
ENSG00000197837 cancer 29616094
ENSG00000197837 breast cancer 29667342
ENSG00000197837 cancers 29721093
ENSG00000197837 breast cancer 29745061
ENSG00000197837 breast cancer 29759486
ENSG00000197837 tumor 30021196
ENSG00000197837 cancer 30394813
ENSG00000197837 cervical cancer 30416981
ENSG00000197837 cancer 30471193
ENSG00000197837 ovarian cancer 30759370
ENSG00000197837 cancer 30807115
ENSG00000197837 AML 30819918
ENSG00000197837 childhood cancer 30929275
ENSG00000197837 breast tumors 30938887
ENSG00000197837 pancreatic cancer 30942624
ENSG00000197837 tumour 31043582
ENSG00000197837 prostate cancer 31061526
ENSG00000197837 tumors 31137727
ENSG00000197837 bladder cancer 31217782
ENSG00000197837 breast cancer 31219579
ENSG00000197837 pancreatic tumor 31312365
ENSG00000197837 Colon Cancer 31471419
ENSG00000197837 Cancer 31575549
ENSG00000197837 tumors 31608230
ENSG00000197837 tumor 31665067
ENSG00000197837 lung cancer 31737580
ENSG00000197837 cancer 31903140
ENSG00000197837 pituitary tumor 8232763
ENSG00000197837 tumors 8668193
ENSG00000197837 tumor 8816806
ENSG00000197837 tumor 9472111
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197837 MESO 0.035 low
ENSG00000197837 STAD 0.02 low
ENSG00000197837 CHOL 0.032 low
ENSG00000197837 PAAD 0.048 low
ENSG00000197837 ACC 0.044 high
ENSG00000197837 LUSC 0.011 low
ENSG00000197837 READ 0.00055 low
ENSG00000197837 LUAD 0.02 low
ENSG00000197837 COAD 0.0053 high
ENSG00000197837 UCS 0.02 low
ENSG00000197837 PRAD 0.034 low
ENSG00000197837 TGCT 0.0012 high
ENSG00000197837 GBM 0.01 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197837 LAML Del 1.854433 0.046480 0.752607 0.047120
ENSG00000197837 LUAD Del 5.093886 0.093788 0.359733 0.271318
ENSG00000197837 READ Del 0.629941 0.067584 0.441577 0.187879
ENSG00000197837 SARC Del 0.925649 0.128064 0.492243 0.307393
ENSG00000197837 GBM Del 1.035389 0.056290 0.522555 0.116118
ENSG00000197837 PAAD Del 1.392759 0.059428 0.396115 0.152174
ENSG00000197837 TGCT Amp 18.567864 0.614392 1.724866 0.980000
ENSG00000197837 BRCA Del 0.938672 0.065661 0.436620 0.165741
ENSG00000197837 STAD Del 1.566681 0.072913 0.412906 0.170068
ENSG00000197837 PRAD Del 3.683194 0.104304 0.513233 0.178862