Ensembl ID ENSG00000197451 Gene ID 3182 Accession 5034
Gene Symbol HNRNPAB Alias ABBP1;HNRPAB Full Name heterogeneous nuclear ribonucleoprotein A/B
Position 5 : 178204533 - 178211163 Length 6631 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

ENSG00000197451 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197451 HNRNPAB 0.44 4.46e-12 KIRC
ENSG00000197451 HNRNPAB 1.06 4.68e-87 BRCA
ENSG00000197451 HNRNPAB 0.78 1.49e-27 LUSC
ENSG00000197451 HNRNPAB 0.45 9.71e-15 PRAD
ENSG00000197451 HNRNPAB 0.70 1.34e-17 KIRP
ENSG00000197451 HNRNPAB 1.02 5.95e-36 UCEC
ENSG00000197451 HNRNPAB 0.68 3.14e-22 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197451 HNRNPAB tumor 15358129
ENSG00000197451 HNRNPAB tumour 18544163
ENSG00000197451 HNRNPAB non-small cell lung cancer 20716340
ENSG00000197451 HNRNPAB lung tumor 24246049
ENSG00000197451 HNRNPAB tumor 24638979
ENSG00000197451 HNRNPAB tumor 30033362
ENSG00000197451 HNRNPAB cancer 30306765
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197451 HNRNPAB MESO 0.033 high
ENSG00000197451 HNRNPAB SARC 0.0092 high
ENSG00000197451 HNRNPAB CHOL 0.04 high
ENSG00000197451 HNRNPAB PAAD 0.023 high
ENSG00000197451 HNRNPAB UCEC 0.0022 high
ENSG00000197451 HNRNPAB ACC 0.016 high
ENSG00000197451 HNRNPAB LGG 0.00097 high
ENSG00000197451 HNRNPAB READ 0.028 low
ENSG00000197451 HNRNPAB LUAD 0.0012 high
ENSG00000197451 HNRNPAB UCS 0.0012 high
ENSG00000197451 HNRNPAB ESCA 0.023 high
ENSG00000197451 HNRNPAB OV 0.0018 low
ENSG00000197451 HNRNPAB DLBC 0.0092 low
ENSG00000197451 HNRNPAB PRAD 0.0044 low
ENSG00000197451 HNRNPAB SKCM 0.00032 high
ENSG00000197451 HNRNPAB LIHC 0.00097 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197451 HNRNPAB LGG Del 4.095460 0.068800 0.414042 0.113060
ENSG00000197451 HNRNPAB KIRP Amp 0.969852 0.061208 0.634107 0.125000
ENSG00000197451 HNRNPAB ACC Amp 1.636341 0.378498 1.219810 0.688889
ENSG00000197451 HNRNPAB GBM Del 0.772239 0.052725 0.442639 0.098787
ENSG00000197451 HNRNPAB SKCM Del 1.966190 0.086140 0.477374 0.302452
ENSG00000197451 HNRNPAB HNSC Del 2.178273 0.070103 0.392156 0.381226
ENSG00000197451 HNRNPAB LIHC Amp 1.220388 0.127223 0.542482 0.354054
ENSG00000197451 HNRNPAB BLCA Del 3.195534 0.114103 0.404257 0.492647
ENSG00000197451 HNRNPAB KIRC Amp 59.407579 0.324820 0.550725 0.625000