Ensembl ID ENSG00000197381 Gene ID 104 Accession 226
Gene Symbol ADARB1 Alias RED1;ADAR2;DRABA2;DRADA2;NEDHYMS Full Name adenosine deaminase RNA specific B1
Position 21 : 45074580 - 45226560 Length 151981 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]

ENSG00000197381 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197381 ADARB1 -2.6 1.10e-21 BLCA
ENSG00000197381 ADARB1 -0.5 7.86e-17 BRCA
ENSG00000197381 ADARB1 -2.1 1.24e-58 LUSC
ENSG00000197381 ADARB1 -2.5 5.90e-13 GBM
ENSG00000197381 ADARB1 -1.2 8.56e-14 STAD
ENSG00000197381 ADARB1 -1.6 2.13e-31 UCEC
ENSG00000197381 ADARB1 -1.7 7.04e-65 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197381 ADARB1 brain tumors 17908822
ENSG00000197381 ADARB1 cancer 19139135
ENSG00000197381 ADARB1 tumors 23135352
ENSG00000197381 ADARB1 tumor 31491024
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197381 ADARB1 SARC 0.008 high
ENSG00000197381 ADARB1 STAD 0.045 high
ENSG00000197381 ADARB1 CHOL 0.029 low
ENSG00000197381 ADARB1 UVM 0.0043 high
ENSG00000197381 ADARB1 UCEC 0.018 low
ENSG00000197381 ADARB1 THCA 0.024 low
ENSG00000197381 ADARB1 ACC 0.007 high
ENSG00000197381 ADARB1 READ 0.0063 high
ENSG00000197381 ADARB1 COAD 0.0082 high
ENSG00000197381 ADARB1 OV 0.0081 high
ENSG00000197381 ADARB1 KIRC 0.0017 low
ENSG00000197381 ADARB1 BLCA 0.026 high
ENSG00000197381 ADARB1 GBM 0.032 high
ENSG00000197381 ADARB1 LIHC 0.017 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197381 ADARB1 LAML Amp 2.896252 0.091359 1.153172 0.062827
ENSG00000197381 ADARB1 READ Del 1.609251 0.095798 0.477377 0.418182
ENSG00000197381 ADARB1 SARC Del 1.021556 0.131435 0.449803 0.237354
ENSG00000197381 ADARB1 HNSC Del 1.058435 0.058695 0.351298 0.392720
ENSG00000197381 ADARB1 STAD Del 1.355480 0.070213 0.383850 0.433107
ENSG00000197381 ADARB1 OV Del 0.908783 0.179507 0.555853 0.393782