Ensembl ID ENSG00000197275 Gene ID 25788 Accession 17228
Gene Symbol RAD54B Alias RDH54 Full Name RAD54 homolog B
Position 8 : 94371960 - 94475115 Length 103156 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]

ENSG00000197275 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197275 RAD54B 1.06 5.50e-17 KIRC
ENSG00000197275 RAD54B 1.30 5.90e-30 HNSC
ENSG00000197275 RAD54B 1.51 3.46e-14 BLCA
ENSG00000197275 RAD54B 1.53 2.74e-67 BRCA
ENSG00000197275 RAD54B 1.91 1.13e-46 COAD
ENSG00000197275 RAD54B 2.49 3.18e-128 LUSC
ENSG00000197275 RAD54B 1.62 6.35e-35 LIHC
ENSG00000197275 RAD54B 1.55 2.67e-24 STAD
ENSG00000197275 RAD54B 2.67 1.64e-13 CESC
ENSG00000197275 RAD54B 1.71 1.69e-45 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197275 RAD54B primary cancer 10362364
ENSG00000197275 RAD54B colon cancer 11782437
ENSG00000197275 RAD54B breast cancer 17405295
ENSG00000197275 RAD54B breast cancer 17585536
ENSG00000197275 RAD54B cancer 18000525
ENSG00000197275 RAD54B colorectal cancer 19218431
ENSG00000197275 RAD54B Colorectal Cancer 24002644
ENSG00000197275 RAD54B tumor 25765654
ENSG00000197275 RAD54B colorectal cancer 26046797
ENSG00000197275 RAD54B cancer 26318585
ENSG00000197275 RAD54B Cancer 27655641
ENSG00000197275 RAD54B HNSCC 27683114
ENSG00000197275 RAD54B colorectal cancer 27902462
ENSG00000197275 RAD54B cancer 28295846
ENSG00000197275 RAD54B cancer 29104272
ENSG00000197275 RAD54B tumors 29296198
ENSG00000197275 RAD54B liver cancer 29956808
ENSG00000197275 RAD54B liver cancer 30394818
ENSG00000197275 RAD54B cancer 30850667
ENSG00000197275 RAD54B breast cancer 31545289
ENSG00000197275 RAD54B lung cancer 31558081
ENSG00000197275 RAD54B breast cancer 31612045
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197275 RAD54B MESO 1e-04 high
ENSG00000197275 RAD54B SARC 0.007 high
ENSG00000197275 RAD54B UVM 0.0019 high
ENSG00000197275 RAD54B PAAD 0.019 high
ENSG00000197275 RAD54B UCEC 0.011 high
ENSG00000197275 RAD54B HNSC 0.028 low
ENSG00000197275 RAD54B LUAD 0.001 high
ENSG00000197275 RAD54B PCPG 0.011 high
ENSG00000197275 RAD54B THYM 0.049 low
ENSG00000197275 RAD54B BRCA 0.0016 high
ENSG00000197275 RAD54B COAD 0.029 low
ENSG00000197275 RAD54B ESCA 0.037 high
ENSG00000197275 RAD54B OV 0.04 low
ENSG00000197275 RAD54B GBM 0.017 low
ENSG00000197275 RAD54B SKCM 0.036 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197275 RAD54B LUAD Amp 1.891125 0.146978 0.590882 0.546512
ENSG00000197275 RAD54B LGG Amp 4.042490 0.088578 0.623757 0.155945
ENSG00000197275 RAD54B READ Amp 1.911053 0.184978 0.796561 0.624242
ENSG00000197275 RAD54B COAD Amp 1.866869 0.090487 0.763421 0.547672
ENSG00000197275 RAD54B LIHC Amp 7.561253 0.251206 1.129692 0.591892
ENSG00000197275 RAD54B TGCT Amp 1.872058 0.173218 0.549005 0.780000
ENSG00000197275 RAD54B BLCA Amp 4.359961 0.274480 0.675140 0.602941
ENSG00000197275 RAD54B BRCA Amp 29.874334 0.420561 1.018384 0.606481
ENSG00000197275 RAD54B STAD Amp 1.033022 0.141863 0.587010 0.612245
ENSG00000197275 RAD54B PRAD Amp 3.357046 0.081588 0.742731 0.315041
ENSG00000197275 RAD54B UVM Amp 8.630052 0.549332 1.490693 0.750000
ENSG00000197275 RAD54B OV Amp 7.460212 0.500524 0.894430 0.583765