Ensembl ID ENSG00000197275 Gene ID 25788 Accession 17228
Gene Symbol RAD54B Alias RDH54 Full Name RAD54 homolog B
Position 8 : 94371960 - 94475115 Length 103156 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]

ENSG00000197275 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197275 1.06 5.50e-17 KIRC
ENSG00000197275 1.30 5.90e-30 HNSC
ENSG00000197275 1.51 3.46e-14 BLCA
ENSG00000197275 1.53 2.74e-67 BRCA
ENSG00000197275 1.91 1.13e-46 COAD
ENSG00000197275 2.49 3.18e-128 LUSC
ENSG00000197275 1.62 6.35e-35 LIHC
ENSG00000197275 1.55 2.67e-24 STAD
ENSG00000197275 2.67 1.64e-13 CESC
ENSG00000197275 1.71 1.69e-45 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197275 primary cancer 10362364
ENSG00000197275 colon cancer 11782437
ENSG00000197275 breast cancer 17405295
ENSG00000197275 breast cancer 17585536
ENSG00000197275 cancer 18000525
ENSG00000197275 colorectal cancer 19218431
ENSG00000197275 Colorectal Cancer 24002644
ENSG00000197275 tumor 25765654
ENSG00000197275 colorectal cancer 26046797
ENSG00000197275 cancer 26318585
ENSG00000197275 Cancer 27655641
ENSG00000197275 HNSCC 27683114
ENSG00000197275 colorectal cancer 27902462
ENSG00000197275 cancer 28295846
ENSG00000197275 cancer 29104272
ENSG00000197275 tumors 29296198
ENSG00000197275 liver cancer 29956808
ENSG00000197275 liver cancer 30394818
ENSG00000197275 cancer 30850667
ENSG00000197275 breast cancer 31545289
ENSG00000197275 lung cancer 31558081
ENSG00000197275 breast cancer 31612045
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197275 MESO 1e-04 high
ENSG00000197275 SARC 0.007 high
ENSG00000197275 UVM 0.0019 high
ENSG00000197275 PAAD 0.019 high
ENSG00000197275 UCEC 0.011 high
ENSG00000197275 HNSC 0.028 low
ENSG00000197275 LUAD 0.001 high
ENSG00000197275 PCPG 0.011 high
ENSG00000197275 THYM 0.049 low
ENSG00000197275 BRCA 0.0016 high
ENSG00000197275 COAD 0.029 low
ENSG00000197275 ESCA 0.037 high
ENSG00000197275 OV 0.04 low
ENSG00000197275 GBM 0.017 low
ENSG00000197275 SKCM 0.036 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197275 LUAD Amp 1.891125 0.146978 0.590882 0.546512
ENSG00000197275 LGG Amp 4.042490 0.088578 0.623757 0.155945
ENSG00000197275 READ Amp 1.911053 0.184978 0.796561 0.624242
ENSG00000197275 COAD Amp 1.866869 0.090487 0.763421 0.547672
ENSG00000197275 LIHC Amp 7.561253 0.251206 1.129692 0.591892
ENSG00000197275 TGCT Amp 1.872058 0.173218 0.549005 0.780000
ENSG00000197275 BLCA Amp 4.359961 0.274480 0.675140 0.602941
ENSG00000197275 BRCA Amp 29.874334 0.420561 1.018384 0.606481
ENSG00000197275 STAD Amp 1.033022 0.141863 0.587010 0.612245
ENSG00000197275 PRAD Amp 3.357046 0.081588 0.742731 0.315041
ENSG00000197275 UVM Amp 8.630052 0.549332 1.490693 0.750000
ENSG00000197275 OV Amp 7.460212 0.500524 0.894430 0.583765