Ensembl ID ENSG00000197238 Gene ID 8363 Accession 4785
Gene Symbol H4C11 Alias H4/e;H4C1;H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4FE;H4-16;H4C12;H4C13;H4C14;H4C15;H4C16;H4F2iv;HIST1H4J;TEVANED2;TEBIVANED2;dJ160A22.2 Full Name H4 clustered histone 11
Position 6 : 27824092 - 27824480 Length 389 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

ENSG00000197238 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197238 2.12 1.16e-21 KIRC
ENSG00000197238 2.43 3.95e-46 BRCA
ENSG00000197238 2.24 1.45e-20 LUSC
ENSG00000197238 1.48 2.96e-14 PRAD
ENSG00000197238 2.05 5.34e-15 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197238 tumors 10344733
ENSG00000197238 tumour 10376979
ENSG00000197238 breast cancer 11682064
ENSG00000197238 Skin tumors 11782361
ENSG00000197238 tumor 12385581
ENSG00000197238 tumor 12579268
ENSG00000197238 gastric cancer 12677198
ENSG00000197238 colorectal cancers 12724227
ENSG00000197238 cancer 12865631
ENSG00000197238 Tumor 12891711
ENSG00000197238 tumor 12939461
ENSG00000197238 colon cancer 12975486
ENSG00000197238 tumours 14614037
ENSG00000197238 cancer 15095300
ENSG00000197238 cancer 15765097
ENSG00000197238 cancer 16131487
ENSG00000197238 tumors 16205112
ENSG00000197238 tumor 16254189
ENSG00000197238 tumors 16270534
ENSG00000197238 breast cancer 16322686
ENSG00000197238 tumours 16404435
ENSG00000197238 tumor 1644858
ENSG00000197238 tumor 16488987
ENSG00000197238 tumor 16497704
ENSG00000197238 tumor 16699174
ENSG00000197238 breast cancer 16707467
ENSG00000197238 breast cancer 16861913
ENSG00000197238 tumor 16863736
ENSG00000197238 tumor 1711413
ENSG00000197238 pediatric tumors 17725108
ENSG00000197238 cancer 17729398
ENSG00000197238 lung cancer 18172270
ENSG00000197238 tumor 18187659
ENSG00000197238 tumour 18384290
ENSG00000197238 cancer 18595135
ENSG00000197238 cancers 18701507
ENSG00000197238 lung cancer 18974389
ENSG00000197238 cancer 19056850
ENSG00000197238 tumor 19086847
ENSG00000197238 DLBCL 19438744
ENSG00000197238 cancer 19509260
ENSG00000197238 pancreatic cancer 19582723
ENSG00000197238 cancer 19961487
ENSG00000197238 ovarian epithelial tumors 20057286
ENSG00000197238 ovarian cancer 20111712
ENSG00000197238 tumor 20534538
ENSG00000197238 cancer 21145737
ENSG00000197238 breast cancers 21321083
ENSG00000197238 ovarian cancer 21355783
ENSG00000197238 cancer 21415707
ENSG00000197238 AML 21968610
ENSG00000197238 cancer 22035019
ENSG00000197238 cancer 22260708
ENSG00000197238 tumor 22279574
ENSG00000197238 cancer 22419068
ENSG00000197238 tumours 22569052
ENSG00000197238 pancreatic cancer 22607671
ENSG00000197238 tumor 22720237
ENSG00000197238 tumor 23019525
ENSG00000197238 tumor 23308215
ENSG00000197238 prostate cancer 23524101
ENSG00000197238 tumor 23553687
ENSG00000197238 tumor 23720754
ENSG00000197238 cancer 23826629
ENSG00000197238 prostate cancer 24065480
ENSG00000197238 thyroid cancer 24155971
ENSG00000197238 lung cancer 24283195
ENSG00000197238 tumor 24778322
ENSG00000197238 cancer 24913909
ENSG00000197238 prostate cancer 24937452
ENSG00000197238 cancers 24953066
ENSG00000197238 tumor 25073158
ENSG00000197238 pancreatic cancer 25152840
ENSG00000197238 colon cancer 25451013
ENSG00000197238 non-small-cell lung cancer 25473433
ENSG00000197238 tumors 25512468
ENSG00000197238 cancers 25512710
ENSG00000197238 breast tumors 25814362
ENSG00000197238 tumour 25864732
ENSG00000197238 tumors 25889518
ENSG00000197238 tumor 25954275
ENSG00000197238 Endometrial Cancer 26222483
ENSG00000197238 cancers 26321891
ENSG00000197238 tumors 26929985
ENSG00000197238 lung cancer 27091080
ENSG00000197238 prostate cancer 27268279
ENSG00000197238 cancer 27322556
ENSG00000197238 cancer 27499010
ENSG00000197238 cancer 27994746
ENSG00000197238 cancer 28139737
ENSG00000197238 tumor 28360947
ENSG00000197238 Prostate Cancer 28609657
ENSG00000197238 tumors 28866885
ENSG00000197238 cancer 28874504
ENSG00000197238 lung cancer 29030587
ENSG00000197238 prostate cancer 29069764
ENSG00000197238 cervical cancer 29184082
ENSG00000197238 tumor 29250163
ENSG00000197238 tumor 29308302
ENSG00000197238 cancer 29401749
ENSG00000197238 cancer 29616094
ENSG00000197238 breast cancer 29667342
ENSG00000197238 cancers 29721093
ENSG00000197238 breast cancer 29745061
ENSG00000197238 breast cancer 29759486
ENSG00000197238 tumor 30021196
ENSG00000197238 Ovarian cancer 30394813
ENSG00000197238 cervical cancer 30416981
ENSG00000197238 cancer 30471193
ENSG00000197238 ovarian cancer 30759370
ENSG00000197238 cancer 30807115
ENSG00000197238 AML 30819918
ENSG00000197238 childhood cancer 30929275
ENSG00000197238 breast tumors 30938887
ENSG00000197238 pancreatic cancer 30942624
ENSG00000197238 tumour 31043582
ENSG00000197238 prostate cancer 31061526
ENSG00000197238 tumors 31137727
ENSG00000197238 bladder cancer 31217782
ENSG00000197238 breast cancer 31219579
ENSG00000197238 pancreatic tumor 31312365
ENSG00000197238 Colon Cancer 31471419
ENSG00000197238 Cancer 31575549
ENSG00000197238 tumors 31608230
ENSG00000197238 tumor 31665067
ENSG00000197238 lung cancer 31737580
ENSG00000197238 cancer 31903140
ENSG00000197238 pituitary tumor 8232763
ENSG00000197238 tumors 8668193
ENSG00000197238 tumor 8816806
ENSG00000197238 tumor 9472111
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197238 MESO 0.014 low
ENSG00000197238 SARC 0.05 low
ENSG00000197238 UVM 0.00042 low
ENSG00000197238 UCEC 0.046 low
ENSG00000197238 ACC 0.0024 low
ENSG00000197238 LUSC 0.0051 low
ENSG00000197238 KIRP 0.022 low
ENSG00000197238 PCPG 0.00065 low
ENSG00000197238 THYM 0.0065 low
ENSG00000197238 BRCA 0.02 high
ENSG00000197238 COAD 0.01 low
ENSG00000197238 ESCA 0.00025 high
ENSG00000197238 DLBC 0.043 low
ENSG00000197238 KIRC 0.0012 high
ENSG00000197238 PRAD 0.029 low
ENSG00000197238 BLCA 0.0054 low
ENSG00000197238 LAML 0.013 high
ENSG00000197238 CESC 0.016 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197238 ESCA Del 0.633934 0.094143 0.370630 0.266304
ENSG00000197238 SKCM Amp 2.227198 0.168055 0.749187 0.517711
ENSG00000197238 LIHC Amp 0.910672 0.118119 0.739976 0.397297
ENSG00000197238 BLCA Amp 1.599452 0.196779 0.508666 0.289216
ENSG00000197238 UVM Amp 2.411362 0.267714 1.169068 0.537500