Ensembl ID ENSG00000197157 Gene ID 27044 Accession 30646
Gene Symbol SND1 Alias p100;TDRD11;Tudor-SN Full Name staphylococcal nuclease and tudor domain containing 1
Position 7 : 127652194 - 128092593 Length 440400 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016]

ENSG00000197157 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000197157 SND1 0.50 9.14e-19 KIRC
ENSG00000197157 SND1 0.34 2.12e-14 BRCA
ENSG00000197157 SND1 0.95 2.46e-30 COAD
ENSG00000197157 SND1 0.67 1.09e-11 KICH
ENSG00000197157 SND1 1.07 7.16e-13 READ
ENSG00000197157 SND1 0.49 1.85e-14 PRAD
ENSG00000197157 SND1 0.48 4.04e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000197157 SND1 colon cancers 17909068
ENSG00000197157 SND1 prostate cancer 19435788
ENSG00000197157 SND1 colon cancers 20883704
ENSG00000197157 SND1 colon cancers 20957089
ENSG00000197157 SND1 breast cancer 21478147
ENSG00000197157 SND1 tumor 21520169
ENSG00000197157 SND1 tumor 22060137
ENSG00000197157 SND1 tumor 22396537
ENSG00000197157 SND1 tumor 22745804
ENSG00000197157 SND1 colon cancer 23065261
ENSG00000197157 SND1 tumor 23878061
ENSG00000197157 SND1 prostate cancer 23995791
ENSG00000197157 SND1 tumor 24918049
ENSG00000197157 SND1 tumors 24981741
ENSG00000197157 SND1 colon cancer 25009642
ENSG00000197157 SND1 breast cancer 25105576
ENSG00000197157 SND1 prostate cancer 25189356
ENSG00000197157 SND1 tumor 25216670
ENSG00000197157 SND1 tumor 25242325
ENSG00000197157 SND1 cancer 25405367
ENSG00000197157 SND1 liver cancer 25494629
ENSG00000197157 SND1 Breast Cancer 25596283
ENSG00000197157 SND1 lung cancer 25650807
ENSG00000197157 SND1 cancer 25965817
ENSG00000197157 SND1 tumors 25985019
ENSG00000197157 SND1 cancer 26323317
ENSG00000197157 SND1 tumors 26351803
ENSG00000197157 SND1 cancers 26808625
ENSG00000197157 SND1 cancers 26997225
ENSG00000197157 SND1 cancer 27238764
ENSG00000197157 SND1 GBM 28160566
ENSG00000197157 SND1 breast cancer 28263968
ENSG00000197157 SND1 tumor 28428278
ENSG00000197157 SND1 cancer 28508063
ENSG00000197157 SND1 tumor 28638727
ENSG00000197157 SND1 lung cancer 29159900
ENSG00000197157 SND1 cancers 29207636
ENSG00000197157 SND1 cancer 29296233
ENSG00000197157 SND1 tumor 30106117
ENSG00000197157 SND1 cancers 30158500
ENSG00000197157 SND1 GBM 30214229
ENSG00000197157 SND1 breast cancer 30216461
ENSG00000197157 SND1 cancer 30321081
ENSG00000197157 SND1 tumor 30365124
ENSG00000197157 SND1 cancers 30509125
ENSG00000197157 SND1 tumor 30619748
ENSG00000197157 SND1 breast cancer 31137748
ENSG00000197157 SND1 cancer 31240215
ENSG00000197157 SND1 oral cancer 31452252
ENSG00000197157 SND1 cancers 31497746
ENSG00000197157 SND1 tumors 31561558
ENSG00000197157 SND1 colorectal cancer 31579913
ENSG00000197157 SND1 breast cancer 31737791
ENSG00000197157 SND1 cervical cancer 31891682
ENSG00000197157 SND1 cancer 31978555
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000197157 SND1 esophageal adenocarcinoma missense_variant 17.35% (76/438) 1 entry
ENSG00000197157 SND1 breast ductal adenocarcinoma sequence_alteration 27.74% (162/584) 3 entries
ENSG00000197157 SND1 prostate adenocarcinoma missense_variant 10.11% (147/1454) 1 entry
ENSG00000197157 SND1 pancreatic ductal adenocarcinoma gene_fusion 11.8% (149/1263) 1 entry
ENSG00000197157 SND1 pancreatic ductal adenocarcinoma sequence_alteration 11.8% (149/1263) 1 entry
ENSG00000197157 SND1 prostate adenocarcinoma sequence_alteration 10.11% (147/1454) 2 entries
ENSG00000197157 SND1 esophageal adenocarcinoma sequence_alteration 17.35% (76/438) 1 entry
ENSG00000197157 SND1 prostate carcinoma sequence_alteration 7.746% (33/426) 2 entries
ENSG00000197157 SND1 colon adenocarcinoma frameshift_variant 3.878% (28/722) 1 entry
ENSG00000197157 SND1 small cell lung carcinoma missense_variant 1.577% (5/317) 1 entry
ENSG00000197157 SND1 clear cell renal carcinoma sequence_alteration 1.058% (13/1229) 1 entry
ENSG00000197157 SND1 rectal adenocarcinoma sequence_alteration 1.357% (3/221) 2 entries
ENSG00000197157 SND1 bladder transitional cell carcinoma missense_variant 2.92% (4/137) 2 entries
ENSG00000197157 SND1 Pancreatic Acinar Cell Carcinoma missense_variant 20.83% (5/24) 2 entries
ENSG00000197157 SND1 breast carcinoma sequence_alteration 0.9922% (14/1411) 1 entry
ENSG00000197157 SND1 colon adenocarcinoma missense_variant 3.878% (28/722) 4 entries
ENSG00000197157 SND1 Pancreatic Acinar Cell Carcinoma gene_fusion 20.83% (5/24) 1 entry
ENSG00000197157 SND1 oral squamous cell carcinoma sequence_alteration 3.415% (7/205) 2 entries
ENSG00000197157 SND1 skin melanoma sequence_alteration 3.516% (34/967) 5 entries
ENSG00000197157 SND1 head and neck squamous cell carcinoma sequence_alteration 2.396% (15/626) 1 entry
ENSG00000197157 SND1 prostate carcinoma missense_variant 7.746% (33/426) 2 entries
ENSG00000197157 SND1 Mantle cell lymphoma sequence_alteration 4.878% (2/41) 1 entry
ENSG00000197157 SND1 basal cell carcinoma missense_variant 6.897% (4/58) 1 entry
ENSG00000197157 SND1 colorectal adenocarcinoma missense_variant 7.821% (89/1138) 2 entries
ENSG00000197157 SND1 female breast carcinoma missense_variant 2.996% (8/267) 1 entry
ENSG00000197157 SND1 melanoma missense_variant 6.931% (7/101) 2 entries
ENSG00000197157 SND1 hepatocellular carcinoma sequence_alteration 3.548% (32/902) 1 entry
ENSG00000197157 SND1 esophageal squamous cell carcinoma frameshift_variant 1.926% (13/675) 2 entries
ENSG00000197157 SND1 ependymoma sequence_alteration 4.348% (2/46) 1 entry
ENSG00000197157 SND1 cecum adenocarcinoma sequence_alteration 6.4% (8/125) 2 entries
ENSG00000197157 SND1 angiosarcoma sequence_alteration 15.38% (2/13) 1 entry
ENSG00000197157 SND1 colon adenocarcinoma sequence_alteration 3.878% (28/722) 5 entries
ENSG00000197157 SND1 colorectal adenocarcinoma frameshift_variant 7.821% (89/1138) 2 entries
ENSG00000197157 SND1 Ampulla of Vater Carcinoma missense_variant 2.353% (2/85) 1 entry
ENSG00000197157 SND1 esophageal squamous cell carcinoma sequence_alteration 1.926% (13/675) 4 entries
ENSG00000197157 SND1 gastric adenocarcinoma missense_variant 3.943% (22/558) 1 entry
ENSG00000197157 SND1 small cell lung carcinoma sequence_alteration 1.577% (5/317) 2 entries
ENSG00000197157 SND1 lung adenocarcinoma sequence_alteration 2.923% (34/1163) 1 entry
ENSG00000197157 SND1 esophageal squamous cell carcinoma missense_variant 1.926% (13/675) 2 entries
ENSG00000197157 SND1 skin melanoma missense_variant 3.516% (34/967) 2 entries
ENSG00000197157 SND1 gastric adenocarcinoma sequence_alteration 3.943% (22/558) 1 entry
ENSG00000197157 SND1 colon adenocarcinoma stop_gained 3.878% (28/722) 2 entries
ENSG00000197157 SND1 kidney Wilms tumor sequence_alteration 0.6289% (2/318) 1 entry
ENSG00000197157 SND1 gastric intestinal type adenocarcinoma sequence_alteration 2.353% (2/85) 1 entry
ENSG00000197157 SND1 bladder carcinoma missense_variant 2.703% (15/555) 1 entry
ENSG00000197157 SND1 female breast carcinoma sequence_alteration 2.996% (8/267) 1 entry
ENSG00000197157 SND1 colorectal adenocarcinoma sequence_alteration 7.821% (89/1138) 4 entries
ENSG00000197157 SND1 chronic lymphocytic leukemia sequence_alteration 2.14% (19/888) 1 entry
ENSG00000197157 SND1 lung adenocarcinoma missense_variant 2.923% (34/1163) 5 entries
ENSG00000197157 SND1 bile duct adenocarcinoma sequence_alteration 1.058% (2/189) 1 entry
ENSG00000197157 SND1 bladder carcinoma sequence_alteration 2.703% (15/555) 1 entry
ENSG00000197157 SND1 brain glioblastoma sequence_alteration 1.188% (11/926) 3 entries
ENSG00000197157 SND1 colon carcinoma sequence_alteration 12.5% (1/8) 1 entry
ENSG00000197157 SND1 melanoma stop_gained 6.931% (7/101) 1 entry
ENSG00000197157 SND1 ovarian serous adenocarcinoma missense_variant 0.1486% (1/673) 1 entry
ENSG00000197157 SND1 Brain Stem Glioblastoma sequence_alteration 1.786% (1/56) 1 entry
ENSG00000197157 SND1 esophageal squamous cell carcinoma stop_gained 1.926% (13/675) 1 entry
ENSG00000197157 SND1 laryngeal squamous cell carcinoma sequence_alteration 7.692% (2/26) 1 entry
ENSG00000197157 SND1 endometrial carcinoma missense_variant 4.348% (1/23) 1 entry
ENSG00000197157 SND1 Pancreatic Acinar Cell Carcinoma sequence_alteration 20.83% (5/24) 1 entry
ENSG00000197157 SND1 bladder transitional cell carcinoma sequence_alteration 2.92% (4/137) 1 entry
ENSG00000197157 SND1 basal cell carcinoma sequence_alteration 6.897% (4/58) 1 entry
ENSG00000197157 SND1 hairy cell leukemia missense_variant 4.762% (1/21) 1 entry
ENSG00000197157 SND1 Invasive Breast Carcinoma missense_variant 2.222% (1/45) 1 entry
ENSG00000197157 SND1 colorectal adenocarcinoma stop_gained 7.821% (89/1138) 1 entry
ENSG00000197157 SND1 nodular melanoma stop_gained 50.0% (1/2) 1 entry
ENSG00000197157 SND1 Olfactory Neuroblastoma missense_variant 100.0% (1/1) 1 entry
ENSG00000197157 SND1 melanoma sequence_alteration 6.931% (7/101) 1 entry
ENSG00000197157 SND1 B-cell acute lymphoblastic leukemia sequence_alteration 1.852% (1/54) 1 entry
ENSG00000197157 SND1 oral squamous cell carcinoma missense_variant 3.415% (7/205) 1 entry
ENSG00000197157 SND1 laryngeal squamous cell carcinoma missense_variant 7.692% (2/26) 1 entry
ENSG00000197157 SND1 Merkel cell skin cancer missense_variant 3.333% (1/30) 1 entry
ENSG00000197157 SND1 Pancreatic Acinar Cell Carcinoma frameshift_variant 20.83% (5/24) 1 entry
ENSG00000197157 SND1 mucosal melanoma stop_gained 7.143% (1/14) 1 entry
ENSG00000197157 SND1 osteosarcoma sequence_alteration 0.8621% (1/116) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000197157 SND1 MESO 0.029 low
ENSG00000197157 SND1 SARC 0.0098 high
ENSG00000197157 SND1 UCEC 0.00011 low
ENSG00000197157 SND1 THCA 0.037 high
ENSG00000197157 SND1 ACC 0.0068 high
ENSG00000197157 SND1 KICH 0.00032 high
ENSG00000197157 SND1 LUAD 0.034 low
ENSG00000197157 SND1 THYM 0.00016 low
ENSG00000197157 SND1 COAD 0.036 high
ENSG00000197157 SND1 ESCA 0.0057 low
ENSG00000197157 SND1 OV 0.029 high
ENSG00000197157 SND1 BLCA 0.0024 high
ENSG00000197157 SND1 GBM 0.0036 high
ENSG00000197157 SND1 SKCM 0.046 high
ENSG00000197157 SND1 CESC 0.0054 high
ENSG00000197157 SND1 LIHC 0.03 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000197157 SND1 LUSC Del 1.785064 0.080604 0.336593 0.173653
ENSG00000197157 SND1 LAML Del 2.834280 0.058384 0.730149 0.125654
ENSG00000197157 SND1 LGG Amp 5.695393 0.107679 0.662322 0.346979
ENSG00000197157 SND1 CESC Del 1.060178 0.074501 0.498156 0.186441
ENSG00000197157 SND1 KIRP Amp 1.434009 0.084489 0.937173 0.607639
ENSG00000197157 SND1 PAAD Del 0.793100 0.047660 0.357603 0.086957
ENSG00000197157 SND1 ESCA Del 5.423977 0.206527 0.380634 0.331522
ENSG00000197157 SND1 SKCM Amp 4.441631 0.228353 0.723080 0.599455
ENSG00000197157 SND1 HNSC Del 11.064241 0.127346 0.396625 0.214559
ENSG00000197157 SND1 STAD Del 2.826732 0.088134 0.338718 0.160998
ENSG00000197157 SND1 UCEC Del 0.763922 0.048408 0.459899 0.113173
ENSG00000197157 SND1 OV Amp 1.520813 0.358569 0.682424 0.480138