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| Ensembl ID | ENSG00000196591 | Gene ID | 3066 | Accession | 4853 |
| Gene Symbol | HDAC2 | Alias | HD2;RPD3;YAF1;KDAC2 | Full Name | histone deacetylase 2 |
| Position | 6 : 113933028 - 114011308 | Length | 78281 bases | Strand | Minus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] | ||||
ENSG00000196591 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000196591 | 0.57 | 1.81e-16 | BRCA | |
| ENSG00000196591 | 0.76 | 1.06e-26 | COAD | |
| ENSG00000196591 | 1.19 | 1.17e-54 | LUSC | |
| ENSG00000196591 | 0.54 | 2.47e-12 | LUAD |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000196591 | breast cancer | 12176973 | |
| ENSG00000196591 | breast cancer | 12527756 | |
| ENSG00000196591 | prostate cancer | 12646234 | |
| ENSG00000196591 | colonic cancer | 15144953 | |
| ENSG00000196591 | colonic cancer | 15477762 | |
| ENSG00000196591 | tumor | 15665816 | |
| ENSG00000196591 | gastric cancer | 15865607 | |
| ENSG00000196591 | colon cancer | 15981215 | |
| ENSG00000196591 | tumor | 16309230 | |
| ENSG00000196591 | tumour | 16638127 | |
| ENSG00000196591 | cancers | 16642021 | |
| ENSG00000196591 | AML | 16914901 | |
| ENSG00000196591 | colon cancer | 17020613 | |
| ENSG00000196591 | Cancer | 17509875 | |
| ENSG00000196591 | tumor | 17718852 | |
| ENSG00000196591 | Cancer | 17760808 | |
| ENSG00000196591 | breast cancer | 17827154 | |
| ENSG00000196591 | intestinal tumor | 17909008 | |
| ENSG00000196591 | breast cancer | 18059533 | |
| ENSG00000196591 | prostate cancer | 18212746 | |
| ENSG00000196591 | cancer | 18264134 | |
| ENSG00000196591 | colon cancer | 18314102 | |
| ENSG00000196591 | colon cancer | 18347167 | |
| ENSG00000196591 | tumours | 18671804 | |
| ENSG00000196591 | tumor | 18834886 | |
| ENSG00000196591 | oral cancer | 18951835 | |
| ENSG00000196591 | colorectal cancer | 19010907 | |
| ENSG00000196591 | cancer | 19057998 | |
| ENSG00000196591 | cervical cancer | 19147762 | |
| ENSG00000196591 | tumor | 19318486 | |
| ENSG00000196591 | pancreatic cancer | 19362090 | |
| ENSG00000196591 | breast cancer | 19372552 | |
| ENSG00000196591 | tumor | 19372580 | |
| ENSG00000196591 | DLBCL | 19438744 | |
| ENSG00000196591 | cancer | 19471575 | |
| ENSG00000196591 | pancreatic cancer | 19528037 | |
| ENSG00000196591 | tumours | 19738609 | |
| ENSG00000196591 | endometrial cancer | 19787250 | |
| ENSG00000196591 | tumors | 19892411 | |
| ENSG00000196591 | cancer | 19997957 | |
| ENSG00000196591 | malignant tumors | 20049841 | |
| ENSG00000196591 | tumors | 20178884 | |
| ENSG00000196591 | cancer | 20190809 | |
| ENSG00000196591 | cancer | 20392638 | |
| ENSG00000196591 | pancreatic cancer | 20398369 | |
| ENSG00000196591 | cancer | 20534591 | |
| ENSG00000196591 | gastric cancer | 20680488 | |
| ENSG00000196591 | pancreatic cancer | 20697349 | |
| ENSG00000196591 | tumour | 20716118 | |
| ENSG00000196591 | cancer | 20802485 | |
| ENSG00000196591 | tumours | 20924032 | |
| ENSG00000196591 | tumours | 20967026 | |
| ENSG00000196591 | tumor | 21080974 | |
| ENSG00000196591 | tumor | 21143702 | |
| ENSG00000196591 | breast cancer | 21188173 | |
| ENSG00000196591 | cancers | 21197454 | |
| ENSG00000196591 | tumor | 21206745 | |
| ENSG00000196591 | tumor | 21270520 | |
| ENSG00000196591 | colorectal cancers | 21290163 | |
| ENSG00000196591 | oral cancer | 21332579 | |
| ENSG00000196591 | bladder cancer | 21507255 | |
| ENSG00000196591 | tumor | 21527555 | |
| ENSG00000196591 | tumour | 21559012 | |
| ENSG00000196591 | metastatic prostate cancer | 21636851 | |
| ENSG00000196591 | tumors | 21713366 | |
| ENSG00000196591 | cancers | 21725353 | |
| ENSG00000196591 | Breast Cancer | 21799737 | |
| ENSG00000196591 | breast cancer | 21860419 | |
| ENSG00000196591 | breast cancer | 21959976 | |
| ENSG00000196591 | mesenchymal tumors | 22037263 | |
| ENSG00000196591 | gastric cancer | 22066420 | |
| ENSG00000196591 | tumors | 22132221 | |
| ENSG00000196591 | pancreatic cancer | 22147512 | |
| ENSG00000196591 | cancer | 22154511 | |
| ENSG00000196591 | cancer | 22159500 | |
| ENSG00000196591 | colon cancer | 22247744 | |
| ENSG00000196591 | tumors | 22384017 | |
| ENSG00000196591 | gastric tumors | 22465428 | |
| ENSG00000196591 | tumor | 22487525 | |
| ENSG00000196591 | lung cancer | 22492270 | |
| ENSG00000196591 | cancers | 22493095 | |
| ENSG00000196591 | prostate cancer | 22531786 | |
| ENSG00000196591 | colorectal cancer | 22562579 | |
| ENSG00000196591 | cancer | 22699815 | |
| ENSG00000196591 | cancers | 22719182 | |
| ENSG00000196591 | cancer | 22800507 | |
| ENSG00000196591 | cancer | 22944197 | |
| ENSG00000196591 | colorectal cancer | 23046873 | |
| ENSG00000196591 | DLBCL | 23109994 | |
| ENSG00000196591 | lung cancer | 23110995 | |
| ENSG00000196591 | cancer | 23159608 | |
| ENSG00000196591 | gastric cancer | 23175521 | |
| ENSG00000196591 | tumor | 23242568 | |
| ENSG00000196591 | tumor | 23389039 | |
| ENSG00000196591 | tumor | 23420051 | |
| ENSG00000196591 | cancer | 23459471 | |
| ENSG00000196591 | tumors | 23493769 | |
| ENSG00000196591 | liver cancer | 23499894 | |
| ENSG00000196591 | tumor | 23544610 | |
| ENSG00000196591 | brain tumor | 23567845 | |
| ENSG00000196591 | tumor | 23625969 | |
| ENSG00000196591 | tumors | 23627572 | |
| ENSG00000196591 | tumor | 23724067 | |
| ENSG00000196591 | rhabdoid tumor | 23764045 | |
| ENSG00000196591 | cancer | 23797109 | |
| ENSG00000196591 | cancer | 23834173 | |
| ENSG00000196591 | cancer | 23926105 | |
| ENSG00000196591 | tumors | 23951168 | |
| ENSG00000196591 | breast cancer | 23975430 | |
| ENSG00000196591 | prostate cancer | 24010203 | |
| ENSG00000196591 | tumor | 24170248 | |
| ENSG00000196591 | ovarian cancer | 24200999 | |
| ENSG00000196591 | colon cancer | 24218540 | |
| ENSG00000196591 | tumour | 24240174 | |
| ENSG00000196591 | Cancer | 24265759 | |
| ENSG00000196591 | tumor | 24377043 | |
| ENSG00000196591 | renal cancer | 24390319 | |
| ENSG00000196591 | lung cancer | 24441677 | |
| ENSG00000196591 | liver cancer | 24448241 | |
| ENSG00000196591 | cancer | 24450491 | |
| ENSG00000196591 | tumor | 24586376 | |
| ENSG00000196591 | liver cancer | 24616922 | |
| ENSG00000196591 | colon cancer | 24622842 | |
| ENSG00000196591 | gastric tumors | 24668547 | |
| ENSG00000196591 | gastric cancer | 24788349 | |
| ENSG00000196591 | cancer | 24905164 | |
| ENSG00000196591 | colon cancer | 24948597 | |
| ENSG00000196591 | tumor | 24952595 | |
| ENSG00000196591 | liver cancer | 24958469 | |
| ENSG00000196591 | cervical cancer | 24965412 | |
| ENSG00000196591 | cancer | 25072962 | |
| ENSG00000196591 | DLBCL | 25076845 | |
| ENSG00000196591 | breast cancer | 25139823 | |
| ENSG00000196591 | tumor | 25275504 | |
| ENSG00000196591 | colorectal cancer | 25307864 | |
| ENSG00000196591 | cancers | 25322459 | |
| ENSG00000196591 | breast cancer | 25341045 | |
| ENSG00000196591 | colorectal cancer | 25447816 | |
| ENSG00000196591 | cancers | 25473896 | |
| ENSG00000196591 | cancer | 25486475 | |
| ENSG00000196591 | cancers | 25525429 | |
| ENSG00000196591 | tumors | 25548579 | |
| ENSG00000196591 | lung cancer | 25605253 | |
| ENSG00000196591 | cancer | 25704882 | |
| ENSG00000196591 | cancer | 25780677 | |
| ENSG00000196591 | liver cancer | 25797269 | |
| ENSG00000196591 | tumors | 25853389 | |
| ENSG00000196591 | lung cancer | 25970771 | |
| ENSG00000196591 | head and neck cancer | 26000099 | |
| ENSG00000196591 | cancer | 26144283 | |
| ENSG00000196591 | cancer | 26209800 | |
| ENSG00000196591 | tumor | 26352599 | |
| ENSG00000196591 | tumor | 26399531 | |
| ENSG00000196591 | colorectal cancer | 26411366 | |
| ENSG00000196591 | tumors | 26425032 | |
| ENSG00000196591 | cancer | 26560874 | |
| ENSG00000196591 | gastric cancer | 26675260 | |
| ENSG00000196591 | tumors | 26676829 | |
| ENSG00000196591 | ovarian cancer | 26683361 | |
| ENSG00000196591 | tumours | 26692909 | |
| ENSG00000196591 | bladder cancer | 26729194 | |
| ENSG00000196591 | colon cancer | 26774139 | |
| ENSG00000196591 | cancers | 26777304 | |
| ENSG00000196591 | colorectal cancer | 26846508 | |
| ENSG00000196591 | AML | 26858310 | |
| ENSG00000196591 | cancers | 26865995 | |
| ENSG00000196591 | cancer | 26883907 | |
| ENSG00000196591 | tumour | 26908329 | |
| ENSG00000196591 | tumor | 26934447 | |
| ENSG00000196591 | Breast cancer | 27065869 | |
| ENSG00000196591 | breast tumor | 27069638 | |
| ENSG00000196591 | tumor | 27130196 | |
| ENSG00000196591 | tumor | 27141386 | |
| ENSG00000196591 | tumor | 27239679 | |
| ENSG00000196591 | cancer | 27250763 | |
| ENSG00000196591 | cancer | 27266347 | |
| ENSG00000196591 | colorectal cancer | 27283986 | |
| ENSG00000196591 | lung cancer | 27356570 | |
| ENSG00000196591 | breast cancer | 27432453 | |
| ENSG00000196591 | lung cancer | 27534532 | |
| ENSG00000196591 | cancer | 27573798 | |
| ENSG00000196591 | thyroid cancer | 27600599 | |
| ENSG00000196591 | tumor | 27614429 | |
| ENSG00000196591 | cancers | 27631103 | |
| ENSG00000196591 | prostate cancer | 27641328 | |
| ENSG00000196591 | non-small cell lung cancer | 27665474 | |
| ENSG00000196591 | tumor | 27705912 | |
| ENSG00000196591 | pancreatic cancer | 27721407 | |
| ENSG00000196591 | cancer | 27761828 | |
| ENSG00000196591 | gastric cancers | 27886118 | |
| ENSG00000196591 | DLBCL | 27886239 | |
| ENSG00000196591 | cancer | 27903278 | |
| ENSG00000196591 | non-small cell lung cancer | 28002023 | |
| ENSG00000196591 | AML | 28030834 | |
| ENSG00000196591 | AML | 28060870 | |
| ENSG00000196591 | GBM | 28099914 | |
| ENSG00000196591 | tumors | 28123574 | |
| ENSG00000196591 | tumors | 28125812 | |
| ENSG00000196591 | AML | 28203711 | |
| ENSG00000196591 | tumors | 28235630 | |
| ENSG00000196591 | pancreatic cancer | 28261641 | |
| ENSG00000196591 | cancer | 28367242 | |
| ENSG00000196591 | tumor | 28434945 | |
| ENSG00000196591 | cancer | 28436261 | |
| ENSG00000196591 | GBM | 28460453 | |
| ENSG00000196591 | tumor | 28505071 | |
| ENSG00000196591 | tumour | 28526090 | |
| ENSG00000196591 | colorectal cancer | 28538837 | |
| ENSG00000196591 | breast cancer | 28560068 | |
| ENSG00000196591 | thyroid cancer | 28600475 | |
| ENSG00000196591 | lung cancer | 28634396 | |
| ENSG00000196591 | breast cancer | 28785170 | |
| ENSG00000196591 | bladder cancer | 28839000 | |
| ENSG00000196591 | Non-Small Cell Lung Cancer | 28839465 | |
| ENSG00000196591 | tumor | 28871696 | |
| ENSG00000196591 | cancer | 28982113 | |
| ENSG00000196591 | Bone cancer | 29096654 | |
| ENSG00000196591 | DLBCL | 29108243 | |
| ENSG00000196591 | tumors | 29136508 | |
| ENSG00000196591 | cancer | 29141538 | |
| ENSG00000196591 | tumor | 29158005 | |
| ENSG00000196591 | cancer | 29190639 | |
| ENSG00000196591 | tumors | 29301348 | |
| ENSG00000196591 | Breast Cancer | 29326587 | |
| ENSG00000196591 | Gastric Cancer | 29333444 | |
| ENSG00000196591 | prostate cancer | 29344347 | |
| ENSG00000196591 | Tumor | 29371906 | |
| ENSG00000196591 | tumour | 29472538 | |
| ENSG00000196591 | Bone Cancer | 29482000 | |
| ENSG00000196591 | AML | 29494986 | |
| ENSG00000196591 | tumor | 29590609 | |
| ENSG00000196591 | Breast Cancer | 29759486 | |
| ENSG00000196591 | pancreatic cancer | 29785119 | |
| ENSG00000196591 | prostate cancer | 29848834 | |
| ENSG00000196591 | cancer | 29882797 | |
| ENSG00000196591 | tumor | 29899271 | |
| ENSG00000196591 | tumor | 30071870 | |
| ENSG00000196591 | tumor | 30096875 | |
| ENSG00000196591 | tongue cancer | 30135512 | |
| ENSG00000196591 | tumors | 30208371 | |
| ENSG00000196591 | cancer | 30250993 | |
| ENSG00000196591 | breast cancer | 30262728 | |
| ENSG00000196591 | gastric cancer | 30266498 | |
| ENSG00000196591 | tumour | 30303525 | |
| ENSG00000196591 | tumor | 30310855 | |
| ENSG00000196591 | cancer | 30369061 | |
| ENSG00000196591 | Tumor | 30416311 | |
| ENSG00000196591 | tumor | 30443188 | |
| ENSG00000196591 | Prostate Cancer | 30453545 | |
| ENSG00000196591 | cancer | 30509303 | |
| ENSG00000196591 | ovarian cancer | 30519361 | |
| ENSG00000196591 | cancer | 30583572 | |
| ENSG00000196591 | breast cancer | 30618185 | |
| ENSG00000196591 | cancer | 30619741 | |
| ENSG00000196591 | Thyroid Cancer | 30669676 | |
| ENSG00000196591 | cancer | 30691229 | |
| ENSG00000196591 | prostate cancer | 30720161 | |
| ENSG00000196591 | tumour | 30737378 | |
| ENSG00000196591 | Tumor | 30818224 | |
| ENSG00000196591 | HNSCC | 30845357 | |
| ENSG00000196591 | cancer | 30868056 | |
| ENSG00000196591 | tumor | 30875794 | |
| ENSG00000196591 | cancer | 30909413 | |
| ENSG00000196591 | pancreatic cancer | 30958531 | |
| ENSG00000196591 | breast cancer | 31059004 | |
| ENSG00000196591 | cancer | 31103900 | |
| ENSG00000196591 | cancer | 31121824 | |
| ENSG00000196591 | cancers | 31254352 | |
| ENSG00000196591 | lung cancer | 31305128 | |
| ENSG00000196591 | cancers | 31312074 | |
| ENSG00000196591 | bone cancer | 31324142 | |
| ENSG00000196591 | tumors | 31399583 | |
| ENSG00000196591 | colorectal cancer | 31524278 | |
| ENSG00000196591 | Cancer | 31620242 | |
| ENSG00000196591 | cancer | 31630802 | |
| ENSG00000196591 | Cancer | 31635225 | |
| ENSG00000196591 | tumor | 31636472 | |
| ENSG00000196591 | non-small-cell lung cancer | 31713888 | |
| ENSG00000196591 | ovarian cancer | 31727867 | |
| ENSG00000196591 | tumor | 31737580 | |
| ENSG00000196591 | ovarian cancer | 31762274 | |
| ENSG00000196591 | cancer | 31805977 | |
| ENSG00000196591 | tumour | 31989434 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000196591 | MESO | 0.00043 | high | ||
| ENSG00000196591 | CHOL | 0.0079 | high | ||
| ENSG00000196591 | UCEC | 0.025 | high | ||
| ENSG00000196591 | THCA | 0.012 | low | ||
| ENSG00000196591 | LGG | 0.00079 | high | ||
| ENSG00000196591 | HNSC | 0.023 | high | ||
| ENSG00000196591 | KICH | 0.0029 | high | ||
| ENSG00000196591 | LUAD | 0.026 | high | ||
| ENSG00000196591 | THYM | 0.00014 | low | ||
| ENSG00000196591 | BRCA | 0.0018 | high | ||
| ENSG00000196591 | UCS | 0.041 | low | ||
| ENSG00000196591 | ESCA | 0.034 | high | ||
| ENSG00000196591 | KIRC | 0.00038 | low | ||
| ENSG00000196591 | GBM | 0.031 | low | ||
| ENSG00000196591 | SKCM | 0.001 | low |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|---|---|---|---|---|---|---|
| ENSG00000196591 | LUAD | Del | 0.775290 | 0.052244 | 0.373301 | 0.507752 | |
| ENSG00000196591 | LGG | Del | 0.675274 | 0.038410 | 0.559119 | 0.148148 | |
| ENSG00000196591 | GBM | Del | 3.178690 | 0.078244 | 0.550270 | 0.256499 | |
| ENSG00000196591 | SKCM | Del | 5.095453 | 0.123015 | 0.565259 | 0.588556 | |
| ENSG00000196591 | LIHC | Del | 1.016323 | 0.070811 | 0.602851 | 0.337838 | |
| ENSG00000196591 | DLBC | Del | 1.747807 | 0.182697 | 0.584665 | 0.312500 | |
| ENSG00000196591 | BLCA | Del | 3.259584 | 0.114634 | 0.378541 | 0.473039 | |
| ENSG00000196591 | BRCA | Del | 4.767699 | 0.091424 | 0.483328 | 0.321296 | |
| ENSG00000196591 | STAD | Del | 0.875336 | 0.063093 | 0.377481 | 0.183673 | |
| ENSG00000196591 | PRAD | Del | 36.866646 | 0.278804 | 0.536728 | 0.306911 | |
| ENSG00000196591 | MESO | Del | 1.467476 | 0.155553 | 0.521054 | 0.459770 | |
| ENSG00000196591 | KIRC | Del | 3.223565 | 0.038754 | 0.449446 | 0.276515 | |
| ENSG00000196591 | OV | Del | 8.354609 | 0.283845 | 0.614874 | 0.583765 |