Ensembl ID
ENSG00000196363
Gene ID
11091
Accession
12757
Gene Symbol
WDR5
Alias
BIG3;SWD3;BIG-3;CFAP89
Full Name
WD repeat domain 5
Position
9 : 134135365 - 134159968
Length
24604 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
ENSG00000196363 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000196363
WDR5
0.36
9.88e-12
KIRC
ENSG00000196363
WDR5
0.52
2.72e-28
BRCA
ENSG00000196363
WDR5
0.69
6.34e-21
COAD
ENSG00000196363
WDR5
1.04
5.65e-37
LUSC
ENSG00000196363
WDR5
0.38
1.55e-13
PRAD
ENSG00000196363
WDR5
0.47
1.48e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000196363
WDR5
cancers
22989411
ENSG00000196363
WDR5
cancer
24279307
ENSG00000196363
WDR5
prostate cancer
24793694
ENSG00000196363
WDR5
cancer
25071008
ENSG00000196363
WDR5
bladder cancer
25656485
ENSG00000196363
WDR5
tumors
25818646
ENSG00000196363
WDR5
liver cancer
25912306
ENSG00000196363
WDR5
AML
26167872
ENSG00000196363
WDR5
Breast Cancer
26355959
ENSG00000196363
WDR5
Cancer
26383167
ENSG00000196363
WDR5
bladder cancer
26484217
ENSG00000196363
WDR5
cancer
26958703
ENSG00000196363
WDR5
gastric cancer
27147598
ENSG00000196363
WDR5
bladder cancers
27192115
ENSG00000196363
WDR5
prostate cancer
27226492
ENSG00000196363
WDR5
prostate cancer
27268279
ENSG00000196363
WDR5
Pancreatic Cancer
27320920
ENSG00000196363
WDR5
cancer
28182322
ENSG00000196363
WDR5
colorectal cancer
28300833
ENSG00000196363
WDR5
lung cancer
28412363
ENSG00000196363
WDR5
Prostate Cancer
28484075
ENSG00000196363
WDR5
Prostate Cancer
28487115
ENSG00000196363
WDR5
Pancreatic Cancer
28741490
ENSG00000196363
WDR5
cancer
28782268
ENSG00000196363
WDR5
gastric cancer
29125890
ENSG00000196363
WDR5
cancers
29241110
ENSG00000196363
WDR5
cancer
29385767
ENSG00000196363
WDR5
HNSCC
29569374
ENSG00000196363
WDR5
tumor
29731905
ENSG00000196363
WDR5
acute myeloid leukemia (AML)
29857126
ENSG00000196363
WDR5
cancers
29889518
ENSG00000196363
WDR5
colon cancer
29925347
ENSG00000196363
WDR5
gastric cancer
29970131
ENSG00000196363
WDR5
gastric cancer
30013768
ENSG00000196363
WDR5
cancer
30089852
ENSG00000196363
WDR5
breast cancer
30226578
ENSG00000196363
WDR5
Gastric Cancer
30274785
ENSG00000196363
WDR5
Cancer
30488017
ENSG00000196363
WDR5
Lung Cancer
30703266
ENSG00000196363
WDR5
prostate cancer
30819158
ENSG00000196363
WDR5
cancer
30865883
ENSG00000196363
WDR5
tumor
31107859
ENSG00000196363
WDR5
Cancer
31360909
ENSG00000196363
WDR5
cancer
31434880
ENSG00000196363
WDR5
tumor
31544250
ENSG00000196363
WDR5
tumour
31685992
ENSG00000196363
WDR5
breast cancer
31752957
ENSG00000196363
WDR5
tumor
31767764
ENSG00000196363
WDR5
cancers
31768400
ENSG00000196363
WDR5
cancers
31858797
ENSG00000196363
WDR5
breast cancer
31938027
ENSG00000196363
WDR5
cancer
31948749
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000196363
WDR5
SARC
0.0091
high
show
ENSG00000196363
WDR5
STAD
0.0027
low
show
ENSG00000196363
WDR5
CHOL
0.011
low
show
ENSG00000196363
WDR5
PAAD
0.00022
low
show
ENSG00000196363
WDR5
THCA
0.042
high
show
ENSG00000196363
WDR5
LUSC
0.013
high
show
ENSG00000196363
WDR5
READ
0.031
low
show
ENSG00000196363
WDR5
KIRP
0.0075
high
show
ENSG00000196363
WDR5
LUAD
0.025
high
show
ENSG00000196363
WDR5
PCPG
0.0072
low
show
ENSG00000196363
WDR5
THYM
0.019
high
show
ENSG00000196363
WDR5
BRCA
0.024
high
show
ENSG00000196363
WDR5
COAD
0.0043
high
show
ENSG00000196363
WDR5
UCS
0.017
high
show
ENSG00000196363
WDR5
OV
0.045
high
show
ENSG00000196363
WDR5
BLCA
0.036
high
show
ENSG00000196363
WDR5
LAML
0.0024
high
show
ENSG00000196363
WDR5
SKCM
0.0016
high
show
ENSG00000196363
WDR5
CESC
0.02
low
show
ENSG00000196363
WDR5
LIHC
0.00028
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000196363
WDR5
SARC
Del
1.950897
0.155868
0.539978
0.233463
ENSG00000196363
WDR5
BRCA
Del
0.630143
0.062553
0.376320
0.273148
ENSG00000196363
WDR5
UCEC
Del
1.448602
0.057447
0.540081
0.243043
ENSG00000196363
WDR5
OV
Del
5.084974
0.247757
0.570607
0.588946
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.