Ensembl ID ENSG00000196230 Gene ID 203068 Accession 20778
Gene Symbol TUBB Alias M40;TUBB1;TUBB5;CDCBM6;CSCSC1;OK/SW-cl.56 Full Name tubulin beta class I
Position 6 : 30717435 - 30725538 Length 8104 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014]

ENSG00000196230 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000196230 TUBB 0.82 1.02e-42 KIRC
ENSG00000196230 TUBB 0.81 2.97e-25 HNSC
ENSG00000196230 TUBB 0.82 3.47e-39 BRCA
ENSG00000196230 TUBB 0.52 3.23e-13 COAD
ENSG00000196230 TUBB 1.24 1.78e-56 LUSC
ENSG00000196230 TUBB 0.81 1.94e-18 KIRP
ENSG00000196230 TUBB 0.79 1.07e-13 UCEC
ENSG00000196230 TUBB 0.69 5.52e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000196230 TUBB non-small-cell lung cancer 11752014
ENSG00000196230 TUBB cancer 15986332
ENSG00000196230 TUBB tumour 16095531
ENSG00000196230 TUBB cancers 19455236
ENSG00000196230 TUBB cancer 20015360
ENSG00000196230 TUBB breast cancer 20842223
ENSG00000196230 TUBB GBM 21807073
ENSG00000196230 TUBB cancer 23321512
ENSG00000196230 TUBB tumours 23639410
ENSG00000196230 TUBB colon cancer 23737015
ENSG00000196230 TUBB gastric cancer 23747515
ENSG00000196230 TUBB tumour 24099319
ENSG00000196230 TUBB colorectal cancer 24618180
ENSG00000196230 TUBB tumor 25975782
ENSG00000196230 TUBB tumour 25991917
ENSG00000196230 TUBB tumor 27556505
ENSG00000196230 TUBB breast cancer 28754978
ENSG00000196230 TUBB tumors 29507682
ENSG00000196230 TUBB cancer 29720836
ENSG00000196230 TUBB tumor 30126203
ENSG00000196230 TUBB Cancer 30890140
ENSG00000196230 TUBB cancer 31177901
ENSG00000196230 TUBB tumor 31242129
ENSG00000196230 TUBB cancer 31508486
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000196230 TUBB UVM 0.042 low
ENSG00000196230 TUBB PAAD 0.021 high
ENSG00000196230 TUBB UCEC 0.027 high
ENSG00000196230 TUBB LGG 0.0014 high
ENSG00000196230 TUBB LUSC 0.041 low
ENSG00000196230 TUBB HNSC 0.011 high
ENSG00000196230 TUBB READ 0.019 low
ENSG00000196230 TUBB LUAD 0.011 high
ENSG00000196230 TUBB PCPG 0.049 low
ENSG00000196230 TUBB THYM 0.0011 low
ENSG00000196230 TUBB COAD 0.024 low
ENSG00000196230 TUBB ESCA 0.021 low
ENSG00000196230 TUBB OV 0.0054 low
ENSG00000196230 TUBB DLBC 0.0092 low
ENSG00000196230 TUBB LAML 0.039 high
ENSG00000196230 TUBB SKCM 0.0049 high
ENSG00000196230 TUBB LIHC 0.0011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000196230 TUBB CESC Amp 2.131438 0.183672 0.616771 0.274576
ENSG00000196230 TUBB SKCM Amp 2.033367 0.162659 0.749712 0.514986
ENSG00000196230 TUBB LIHC Amp 2.143254 0.149391 0.770293 0.402703
ENSG00000196230 TUBB BLCA Amp 1.108418 0.179525 0.496008 0.284314
ENSG00000196230 TUBB STAD Amp 1.234162 0.148369 0.489020 0.244898
ENSG00000196230 TUBB UVM Amp 2.411362 0.267714 1.168829 0.537500
ENSG00000196230 TUBB OV Amp 1.221916 0.347970 0.672202 0.468048