Ensembl ID ENSG00000189060 Gene ID 3005 Accession 4714
Gene Symbol H1-0 Alias H10;H1.0;H1F0;H1FV Full Name H1.0 linker histone
Position 22 : 37805229 - 37807432 Length 2204 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]

ENSG00000189060 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000189060 -1.9 1.85e-68 KIRC
ENSG00000189060 0.79 9.62e-26 BRCA
ENSG00000189060 1.43 4.26e-35 LUSC
ENSG00000189060 1.16 9.50e-33 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000189060 tumors 10477169
ENSG00000189060 tumors 1269855
ENSG00000189060 tumours 1284124
ENSG00000189060 tumor 1381622
ENSG00000189060 liver tumor 1618930
ENSG00000189060 tumor 1694982
ENSG00000189060 GBM 17593975
ENSG00000189060 tumor 18241678
ENSG00000189060 tumors 19538164
ENSG00000189060 metastatic tumors 2015714
ENSG00000189060 tumour 20229286
ENSG00000189060 breast cancer 21723901
ENSG00000189060 tumour 22238065
ENSG00000189060 tumor 22589538
ENSG00000189060 tumor 2328774
ENSG00000189060 tumor 23812966
ENSG00000189060 tumor 24806546
ENSG00000189060 GBM 25133526
ENSG00000189060 tumour 25283551
ENSG00000189060 breast cancer 25739083
ENSG00000189060 tumours 26171933
ENSG00000189060 tumor 26186119
ENSG00000189060 tumor 26218790
ENSG00000189060 tumor 27313150
ENSG00000189060 Cancer 27633859
ENSG00000189060 tumor 27708074
ENSG00000189060 tumour 27893815
ENSG00000189060 tumor 27918638
ENSG00000189060 liver tumor 281557
ENSG00000189060 breast cancer 28536618
ENSG00000189060 cancer 28545132
ENSG00000189060 tumor 29437590
ENSG00000189060 cancer 29937991
ENSG00000189060 tumour 3033141
ENSG00000189060 tumor 31675152
ENSG00000189060 AML 31681584
ENSG00000189060 tumor 320348
ENSG00000189060 tumor 3265705
ENSG00000189060 metastatic tumor 3357332
ENSG00000189060 tumor 3567891
ENSG00000189060 liver tumor 3601320
ENSG00000189060 liver tumor 3760037
ENSG00000189060 tumor 4091528
ENSG00000189060 tumor 470220
ENSG00000189060 GBM 6083703
ENSG00000189060 tumors 6209187
ENSG00000189060 breast cancer 6279951
ENSG00000189060 liver tumors 6549550
ENSG00000189060 tumor 7671250
ENSG00000189060 tumor 7715903
ENSG00000189060 tumour 8220251
ENSG00000189060 tumor 8287619
ENSG00000189060 tumor 8385575
ENSG00000189060 tumors 8486531
ENSG00000189060 tumor 9049831
ENSG00000189060 tumor 9157980
ENSG00000189060 tumor 9458372
ENSG00000189060 tumor 9877246
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000189060 MESO 0.0033 high
ENSG00000189060 PAAD 0.0096 high
ENSG00000189060 THCA 0.0012 high
ENSG00000189060 HNSC 0.049 high
ENSG00000189060 KICH 0.00017 high
ENSG00000189060 LUAD 0.02 high
ENSG00000189060 BRCA 0.0031 low
ENSG00000189060 COAD 0.024 high
ENSG00000189060 UCS 0.01 low
ENSG00000189060 ESCA 0.015 low
ENSG00000189060 DLBC 0.022 low
ENSG00000189060 KIRC 0.019 low
ENSG00000189060 PRAD 0.0063 low
ENSG00000189060 LAML 0.0067 low
ENSG00000189060 GBM 0.0026 low
ENSG00000189060 SKCM 0.0032 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000189060 THYM Del 0.970980 0.043130 0.436505 0.130081
ENSG00000189060 SKCM Amp 1.524178 0.147355 0.568195 0.389646