Ensembl ID ENSG00000188846 Gene ID 9045 Accession 10305
Gene Symbol RPL14 Alias L14;RL14;eL14;hRL14;CTG-B33;CAG-ISL-7 Full Name ribosomal protein L14
Position 3 : 40457292 - 40468587 Length 11296 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

ENSG00000188846 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000188846 RPL14 -0.7 8.70e-12 HNSC
ENSG00000188846 RPL14 0.61 4.47e-11 PRAD
ENSG00000188846 RPL14 0.87 2.18e-13 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000188846 RPL14 tumor 16316724
ENSG00000188846 RPL14 cancer 17701052
ENSG00000188846 RPL14 oral cancers 9920051
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000188846 RPL14 MESO 0.028 low
ENSG00000188846 RPL14 SARC 0.021 high
ENSG00000188846 RPL14 CHOL 0.012 high
ENSG00000188846 RPL14 PAAD 0.025 high
ENSG00000188846 RPL14 UCEC 0.028 low
ENSG00000188846 RPL14 ACC 0.0088 high
ENSG00000188846 RPL14 READ 0.0098 low
ENSG00000188846 RPL14 KICH 0.0068 high
ENSG00000188846 RPL14 THYM 0.0063 low
ENSG00000188846 RPL14 BRCA 0.0018 low
ENSG00000188846 RPL14 ESCA 0.012 high
ENSG00000188846 RPL14 OV 0.022 low
ENSG00000188846 RPL14 KIRC 0.0051 high
ENSG00000188846 RPL14 TGCT 0.049 low
ENSG00000188846 RPL14 GBM 0.045 low
ENSG00000188846 RPL14 LIHC 0.0062 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000188846 RPL14 CHOL Del 0.615751 0.195478 0.623115 0.805556
ENSG00000188846 RPL14 BRCA Del 9.332064 0.112175 0.441040 0.267593
ENSG00000188846 RPL14 STAD Del 2.215432 0.081260 0.333018 0.310658
ENSG00000188846 RPL14 MESO Del 7.043281 0.322306 0.538252 0.344828
ENSG00000188846 RPL14 KIRC Del 50.594206 0.178801 0.516467 0.880682