Ensembl ID ENSG00000188612 Gene ID 6613 Accession 11125
Gene Symbol SUMO2 Alias HSMT3;SMT3B;SUMO3;Smt3A;SMT3H2 Full Name small ubiquitin like modifier 2
Position 17 : 75165586 - 75182959 Length 17374 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

ENSG00000188612 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000188612 SUMO2 0.46 7.67e-19 BRCA
ENSG00000188612 SUMO2 -0.7 8.25e-17 KICH
ENSG00000188612 SUMO2 0.71 6.14e-21 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000188612 SUMO2 MESO 0.013 low
ENSG00000188612 SUMO2 SARC 0.01 high
ENSG00000188612 SUMO2 CHOL 0.026 high
ENSG00000188612 SUMO2 THCA 0.013 low
ENSG00000188612 SUMO2 ACC 0.0012 high
ENSG00000188612 SUMO2 LGG 0.0011 low
ENSG00000188612 SUMO2 LUSC 0.014 low
ENSG00000188612 SUMO2 HNSC 0.0012 high
ENSG00000188612 SUMO2 KIRP 0.00019 high
ENSG00000188612 SUMO2 KICH 0.00021 high
ENSG00000188612 SUMO2 LUAD 0.01 high
ENSG00000188612 SUMO2 PCPG 0.0059 high
ENSG00000188612 SUMO2 THYM 0.019 low
ENSG00000188612 SUMO2 BRCA 0.048 low
ENSG00000188612 SUMO2 UCS 0.047 low
ENSG00000188612 SUMO2 ESCA 0.026 high
ENSG00000188612 SUMO2 OV 0.0019 low
ENSG00000188612 SUMO2 KIRC 0.016 high
ENSG00000188612 SUMO2 BLCA 5e-04 low
ENSG00000188612 SUMO2 LAML 0.042 low
ENSG00000188612 SUMO2 SKCM 0.001 low
ENSG00000188612 SUMO2 CESC 0.0096 low
ENSG00000188612 SUMO2 LIHC 0.0025 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000188612 SUMO2 LUSC Amp 1.936474 0.233702 0.450176 0.469062
ENSG00000188612 SUMO2 LUAD Amp 2.789370 0.165310 0.407117 0.498062
ENSG00000188612 SUMO2 LGG Amp 2.516991 0.070210 0.582991 0.079922
ENSG00000188612 SUMO2 CESC Amp 4.297122 0.246623 0.707703 0.244068
ENSG00000188612 SUMO2 UCS Amp 0.799683 0.510805 0.722966 0.535714
ENSG00000188612 SUMO2 GBM Amp 0.713041 0.066946 0.415184 0.140381
ENSG00000188612 SUMO2 PAAD Del 3.330359 0.091201 0.350607 0.222826
ENSG00000188612 SUMO2 SKCM Amp 5.669251 0.258865 0.551263 0.351499
ENSG00000188612 SUMO2 LIHC Amp 8.474266 0.265708 0.672562 0.381081
ENSG00000188612 SUMO2 BLCA Amp 2.032497 0.210732 0.465711 0.473039
ENSG00000188612 SUMO2 BRCA Amp 21.936150 0.364073 0.652991 0.370370
ENSG00000188612 SUMO2 UCEC Amp 3.652659 0.161661 0.587823 0.166976
ENSG00000188612 SUMO2 OV Amp 1.464057 0.356674 0.537313 0.343696