Ensembl ID ENSG00000188529 Gene ID 10772 Accession 16713
Gene Symbol SRSF10 Alias NSSR;TASR;SRp38;TASR1;TASR2;FUSIP1;FUSIP2;SFRS13;SRrp40;SFRS13A;PPP1R149 Full Name serine and arginine rich splicing factor 10
Position 1 : 23964347 - 23980356 Length 16010 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ENSG00000188529 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000188529 SRSF10 0.63 1.87e-16 STAD
ENSG00000188529 SRSF10 0.34 1.54e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000188529 SRSF10 tumours 19686582
ENSG00000188529 SRSF10 breast cancer 21589938
ENSG00000188529 SRSF10 cancer 21811587
ENSG00000188529 SRSF10 breast cancer 22838641
ENSG00000188529 SRSF10 colon cancer 25091051
ENSG00000188529 SRSF10 tumor 25821520
ENSG00000188529 SRSF10 cancer 27851963
ENSG00000188529 SRSF10 cancer 29429992
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000188529 SRSF10 MESO 0.0064 low
ENSG00000188529 SRSF10 SARC 0.00088 high
ENSG00000188529 SRSF10 STAD 0.027 low
ENSG00000188529 SRSF10 UVM 0.044 high
ENSG00000188529 SRSF10 ACC 0.016 high
ENSG00000188529 SRSF10 LUSC 0.026 low
ENSG00000188529 SRSF10 HNSC 0.0062 low
ENSG00000188529 SRSF10 READ 0.0066 low
ENSG00000188529 SRSF10 KICH 0.0043 high
ENSG00000188529 SRSF10 PCPG 0.0024 high
ENSG00000188529 SRSF10 THYM 0.0064 low
ENSG00000188529 SRSF10 BRCA 0.012 high
ENSG00000188529 SRSF10 COAD 0.024 low
ENSG00000188529 SRSF10 UCS 0.013 low
ENSG00000188529 SRSF10 KIRC 0.018 high
ENSG00000188529 SRSF10 BLCA 0.0076 low
ENSG00000188529 SRSF10 GBM 0.0081 high
ENSG00000188529 SRSF10 SKCM 0.00019 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000188529 SRSF10 CHOL Del 20.935107 1.061598 0.678521 0.805556
ENSG00000188529 SRSF10 LUSC Del 4.984657 0.113019 0.386916 0.449102
ENSG00000188529 SRSF10 LUAD Del 1.144592 0.057490 0.292193 0.244186
ENSG00000188529 SRSF10 CESC Del 1.502765 0.082575 0.448473 0.111864
ENSG00000188529 SRSF10 KIRP Del 6.501430 0.076312 0.594947 0.177083
ENSG00000188529 SRSF10 READ Del 8.432720 0.206688 0.447014 0.448485
ENSG00000188529 SRSF10 COAD Del 18.827576 0.161797 0.453365 0.361419
ENSG00000188529 SRSF10 GBM Del 5.980911 0.099634 0.549004 0.102253
ENSG00000188529 SRSF10 PAAD Del 2.191029 0.074138 0.349050 0.320652
ENSG00000188529 SRSF10 ESCA Del 0.894600 0.102381 0.349363 0.364130
ENSG00000188529 SRSF10 SKCM Del 1.515384 0.079650 0.449609 0.188011
ENSG00000188529 SRSF10 HNSC Del 2.408384 0.072177 0.363283 0.180077
ENSG00000188529 SRSF10 LIHC Del 14.710558 0.200144 0.542842 0.367568
ENSG00000188529 SRSF10 PCPG Del 2.020882 0.085543 0.674895 0.623457
ENSG00000188529 SRSF10 BRCA Del 31.890415 0.181945 0.422617 0.405556
ENSG00000188529 SRSF10 STAD Del 3.907062 0.098691 0.353437 0.247166
ENSG00000188529 SRSF10 UCEC Del 9.659210 0.118107 0.503584 0.135436
ENSG00000188529 SRSF10 MESO Del 3.601791 0.227730 0.527430 0.321839
ENSG00000188529 SRSF10 KIRC Del 7.061267 0.055158 0.419977 0.181818
ENSG00000188529 SRSF10 UVM Del 1.628635 0.094732 0.814634 0.300000
ENSG00000188529 SRSF10 OV Del 24.488417 0.413613 0.549294 0.421416