Ensembl ID ENSG00000187531 Gene ID 51547 Accession 14935
Gene Symbol SIRT7 Alias SIR2L7 Full Name sirtuin 7
Position 17 : 81911939 - 81921323 Length 9385 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

ENSG00000187531 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000187531 0.85 4.33e-33 KIRC
ENSG00000187531 0.95 6.51e-47 BRCA
ENSG00000187531 0.94 1.26e-23 LUSC
ENSG00000187531 1.12 1.75e-26 KIRP
ENSG00000187531 1.00 5.45e-22 LIHC
ENSG00000187531 1.11 5.64e-27 UCEC
ENSG00000187531 0.95 1.41e-30 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000187531 breast cancer 17003781
ENSG00000187531 cancer 22403547
ENSG00000187531 cancer 22698398
ENSG00000187531 cancer 22704201
ENSG00000187531 cancer 22722849
ENSG00000187531 tumor 23016857
ENSG00000187531 cancer 23079745
ENSG00000187531 cancer 24020007
ENSG00000187531 tumor 24113281
ENSG00000187531 cancer 24133372
ENSG00000187531 cancer 24335889
ENSG00000187531 bladder cancer 24396870
ENSG00000187531 bladder cancer 24512851
ENSG00000187531 cancer 24536059
ENSG00000187531 tumor 25085992
ENSG00000187531 tumor 25416589
ENSG00000187531 cancer 25435428
ENSG00000187531 cancer 25486244
ENSG00000187531 cancer 25503141
ENSG00000187531 cervical cancer 25794641
ENSG00000187531 tumor 25861255
ENSG00000187531 cancer 25907989
ENSG00000187531 Ovarian Cancer 25921180
ENSG00000187531 cancer 25923013
ENSG00000187531 cancer 25936698
ENSG00000187531 tumor 26063372
ENSG00000187531 tumour 26121130
ENSG00000187531 tumor 26420294
ENSG00000187531 tumors 26425032
ENSG00000187531 tumor 26442981
ENSG00000187531 tumor 26631040
ENSG00000187531 tumor 26701732
ENSG00000187531 lung cancer 26766902
ENSG00000187531 tumor 26798421
ENSG00000187531 cancer 26978351
ENSG00000187531 breast cancer 27080717
ENSG00000187531 cancer 27226812
ENSG00000187531 tumors 27379175
ENSG00000187531 tumor 27498548
ENSG00000187531 cancer 27500936
ENSG00000187531 non-small cell lung cancer 27599551
ENSG00000187531 cancer 27659520
ENSG00000187531 tumor 27916001
ENSG00000187531 tumor 28067587
ENSG00000187531 cancer 28147277
ENSG00000187531 cancer 28258519
ENSG00000187531 cancer 28426094
ENSG00000187531 tumor 28435470
ENSG00000187531 tumor 28445974
ENSG00000187531 basal-like breast cancer 28560068
ENSG00000187531 cancer 28661724
ENSG00000187531 breast cancer 28827661
ENSG00000187531 breast cancer 28944911
ENSG00000187531 tumor 28979804
ENSG00000187531 gastric cancer 29088792
ENSG00000187531 prostate cancer 29100388
ENSG00000187531 breast cancer 29123410
ENSG00000187531 tumor 29152116
ENSG00000187531 breast cancer 29231244
ENSG00000187531 Cancer 29438839
ENSG00000187531 gastric cancer 29953672
ENSG00000187531 tumor 30001742
ENSG00000187531 breast cancers 30038266
ENSG00000187531 thyroid cancer 30093629
ENSG00000187531 lung cancer 30237737
ENSG00000187531 cancer 30282801
ENSG00000187531 non-small cell lung cancer 30348528
ENSG00000187531 tumor 30503501
ENSG00000187531 tumor 30510540
ENSG00000187531 tumor 30627559
ENSG00000187531 cancer 30653310
ENSG00000187531 liver cancer 30756531
ENSG00000187531 tumor 30761005
ENSG00000187531 tumors 30875794
ENSG00000187531 cancer 30944854
ENSG00000187531 cancer 31025603
ENSG00000187531 ovarian cancer 31113446
ENSG00000187531 tumor 31121824
ENSG00000187531 liver cancer 31196136
ENSG00000187531 tumor 31572453
ENSG00000187531 lung cancer 31613681
ENSG00000187531 tumors 31678303
ENSG00000187531 non-small cell lung cancer 31683458
ENSG00000187531 tumor 31843644
ENSG00000187531 cancer 31863763
ENSG00000187531 breast cancer 31970414
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000187531 SARC 0.019 low
ENSG00000187531 STAD 0.00016 low
ENSG00000187531 CHOL 0.041 high
ENSG00000187531 UVM 0.0038 high
ENSG00000187531 UCEC 0.025 high
ENSG00000187531 THCA 0.036 low
ENSG00000187531 ACC 0.011 high
ENSG00000187531 LGG 0.011 high
ENSG00000187531 LUSC 0.0093 high
ENSG00000187531 HNSC 0.031 low
ENSG00000187531 KIRP 0.021 high
ENSG00000187531 PCPG 0.043 low
ENSG00000187531 THYM 0.0019 low
ENSG00000187531 BRCA 0.0082 low
ENSG00000187531 COAD 0.049 high
ENSG00000187531 ESCA 0.022 high
ENSG00000187531 OV 0.036 low
ENSG00000187531 BLCA 0.0059 low
ENSG00000187531 SKCM 0.03 low
ENSG00000187531 CESC 0.044 low
ENSG00000187531 LIHC 2e-04 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000187531 LUSC Del 0.828296 0.067423 0.332482 0.171657
ENSG00000187531 LUAD Amp 3.368468 0.176078 0.405624 0.500000
ENSG00000187531 LGG Amp 2.465343 0.069551 0.490975 0.093567
ENSG00000187531 CESC Del 1.839225 0.088447 0.461774 0.149153
ENSG00000187531 ACC Amp 0.854243 0.266635 0.767339 0.188889
ENSG00000187531 ESCA Del 0.663808 0.095320 0.377013 0.195652
ENSG00000187531 SKCM Amp 5.302479 0.250393 0.568379 0.329700
ENSG00000187531 HNSC Del 1.499596 0.063466 0.357491 0.111111
ENSG00000187531 LIHC Amp 12.329930 0.321119 0.713362 0.383784
ENSG00000187531 BLCA Amp 2.265064 0.217753 0.469934 0.470588
ENSG00000187531 OV Amp 3.200603 0.408379 0.565256 0.357513