Ensembl ID ENSG00000186666 Gene ID 144233 Accession 27050
Gene Symbol BCDIN3D Alias NA Full Name BCDIN3 domain containing RNA methyltransferase
Position 12 : 49836043 - 49843106 Length 7064 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]

ENSG00000186666 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000186666 BCDIN3D -0.3 4.21e-11 KIRC
ENSG00000186666 BCDIN3D 0.42 2.41e-16 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000186666 BCDIN3D breast cancer 23063121
ENSG00000186666 BCDIN3D breast cancer 27259993
ENSG00000186666 BCDIN3D breast cancer 28119416
ENSG00000186666 BCDIN3D breast cancers 30127802
ENSG00000186666 BCDIN3D breast cancer 31145769
ENSG00000186666 BCDIN3D cancer 31329584
ENSG00000186666 BCDIN3D breast cancer 31919512
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000186666 BCDIN3D MESO 0.00023 low
ENSG00000186666 BCDIN3D SARC 6e-04 low
ENSG00000186666 BCDIN3D STAD 0.012 low
ENSG00000186666 BCDIN3D CHOL 0.0087 low
ENSG00000186666 BCDIN3D UVM 0.0052 high
ENSG00000186666 BCDIN3D PAAD 0.002 low
ENSG00000186666 BCDIN3D UCEC 0.017 high
ENSG00000186666 BCDIN3D THCA 0.025 low
ENSG00000186666 BCDIN3D ACC 0.033 high
ENSG00000186666 BCDIN3D LUSC 0.001 low
ENSG00000186666 BCDIN3D HNSC 0.0093 low
ENSG00000186666 BCDIN3D KIRP 0.049 low
ENSG00000186666 BCDIN3D KICH 0.011 high
ENSG00000186666 BCDIN3D LUAD 0.011 low
ENSG00000186666 BCDIN3D PCPG 0.0012 high
ENSG00000186666 BCDIN3D THYM 0.033 low
ENSG00000186666 BCDIN3D BRCA 0.024 high
ENSG00000186666 BCDIN3D COAD 0.0026 low
ENSG00000186666 BCDIN3D OV 0.00078 low
ENSG00000186666 BCDIN3D KIRC 0.0015 low
ENSG00000186666 BCDIN3D TGCT 0.027 low
ENSG00000186666 BCDIN3D BLCA 0.00017 low
ENSG00000186666 BCDIN3D GBM 0.026 low
ENSG00000186666 BCDIN3D SKCM 0.0091 low
ENSG00000186666 BCDIN3D LIHC 0.0094 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000186666 BCDIN3D LGG Del 0.618790 0.037777 0.426690 0.130604
ENSG00000186666 BCDIN3D PAAD Del 0.927232 0.050602 0.381066 0.179348