Ensembl ID ENSG00000186298 Gene ID 5501 Accession 9283
Gene Symbol PPP1CC Alias PP1C;PP-1G;PPP1G Full Name protein phosphatase 1 catalytic subunit gamma
Position 12 : 110719680 - 110742939 Length 23260 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

ENSG00000186298 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000186298 PPP1CC 0.49 2.18e-24 KIRC
ENSG00000186298 PPP1CC 0.70 1.14e-15 KICH
ENSG00000186298 PPP1CC 0.62 3.81e-21 LUSC
ENSG00000186298 PPP1CC 0.47 1.68e-12 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000186298 PPP1CC tumor 29285244
ENSG00000186298 PPP1CC Cancer 30158517
ENSG00000186298 PPP1CC ovarian cancer 31216618
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000186298 PPP1CC STAD 0.022 low
ENSG00000186298 PPP1CC UVM 0.008 low
ENSG00000186298 PPP1CC PAAD 0.0043 high
ENSG00000186298 PPP1CC LGG 0.028 high
ENSG00000186298 PPP1CC LUSC 0.033 low
ENSG00000186298 PPP1CC HNSC 0.0072 high
ENSG00000186298 PPP1CC READ 0.025 low
ENSG00000186298 PPP1CC KIRP 0.0053 high
ENSG00000186298 PPP1CC LUAD 0.029 high
ENSG00000186298 PPP1CC ESCA 0.0071 high
ENSG00000186298 PPP1CC KIRC 0.0043 low
ENSG00000186298 PPP1CC PRAD 0.0091 high
ENSG00000186298 PPP1CC LAML 0.0038 high
ENSG00000186298 PPP1CC GBM 0.011 low
ENSG00000186298 PPP1CC SKCM 0.026 low
ENSG00000186298 PPP1CC CESC 0.00015 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000186298 PPP1CC CHOL Del 0.848275 0.219537 0.589045 0.222222
ENSG00000186298 PPP1CC LGG Del 1.013479 0.042631 0.426904 0.124756
ENSG00000186298 PPP1CC PAAD Del 1.340810 0.058840 0.351339 0.222826
ENSG00000186298 PPP1CC SKCM Del 1.619716 0.081125 0.444947 0.245232
ENSG00000186298 PPP1CC BRCA Del 2.674719 0.079294 0.380139 0.191667
ENSG00000186298 PPP1CC OV Del 3.113373 0.221018 0.557278 0.328152