Ensembl ID ENSG00000185745 Gene ID 3434 Accession 5407
Gene Symbol IFIT1 Alias C56;P56;G10P1;IFI56;ISG56;IFI-56;IFIT-1;IFNAI1;RNM561;IFI-56K Full Name interferon induced protein with tetratricopeptide repeats 1
Position 10 : 89392546 - 89406487 Length 13942 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]

ENSG00000185745 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000185745 IFIT1 2.12 2.20e-17 HNSC
ENSG00000185745 IFIT1 1.42 6.08e-20 BRCA
ENSG00000185745 IFIT1 -2.5 1.00e-30 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000185745 IFIT1 tumor 10644362
ENSG00000185745 IFIT1 cervical cancer 11765912
ENSG00000185745 IFIT1 tumors 20374648
ENSG00000185745 IFIT1 breast cancer 23528130
ENSG00000185745 IFIT1 cancer 24086395
ENSG00000185745 IFIT1 tumor 24725474
ENSG00000185745 IFIT1 tumor 24870930
ENSG00000185745 IFIT1 tumors 25076125
ENSG00000185745 IFIT1 tumors 25503978
ENSG00000185745 IFIT1 breast cancer 25588716
ENSG00000185745 IFIT1 tumors 26769142
ENSG00000185745 IFIT1 tumor 26980050
ENSG00000185745 IFIT1 cancer 27411336
ENSG00000185745 IFIT1 cancer 27454254
ENSG00000185745 IFIT1 tumor 28878208
ENSG00000185745 IFIT1 cancer 29245969
ENSG00000185745 IFIT1 cancer 29681787
ENSG00000185745 IFIT1 cancer 30389917
ENSG00000185745 IFIT1 tumor 30626937
ENSG00000185745 IFIT1 oral cancer 31538341
ENSG00000185745 IFIT1 tumor 31977029
ENSG00000185745 IFIT1 tumors 3601261
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000185745 IFIT1 MESO 0.00099 low
ENSG00000185745 IFIT1 STAD 0.017 high
ENSG00000185745 IFIT1 CHOL 0.032 low
ENSG00000185745 IFIT1 UVM 0.012 high
ENSG00000185745 IFIT1 PAAD 0.016 high
ENSG00000185745 IFIT1 UCEC 0.002 high
ENSG00000185745 IFIT1 THCA 0.014 low
ENSG00000185745 IFIT1 ACC 0.017 high
ENSG00000185745 IFIT1 LGG 0.0015 low
ENSG00000185745 IFIT1 HNSC 0.023 high
ENSG00000185745 IFIT1 KIRP 0.00011 low
ENSG00000185745 IFIT1 THYM 0.024 high
ENSG00000185745 IFIT1 OV 0.018 low
ENSG00000185745 IFIT1 DLBC 0.00022 high
ENSG00000185745 IFIT1 PRAD 0.023 high
ENSG00000185745 IFIT1 BLCA 0.0036 high
ENSG00000185745 IFIT1 LAML 0.00049 high
ENSG00000185745 IFIT1 GBM 0.00039 low
ENSG00000185745 IFIT1 SKCM 0.00018 low
ENSG00000185745 IFIT1 LIHC 0.028 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000185745 IFIT1 LUSC Del 4.531804 0.108697 0.379358 0.518962
ENSG00000185745 IFIT1 LGG Del 0.874518 0.040942 0.547906 0.224172
ENSG00000185745 IFIT1 CESC Del 2.398697 0.097622 0.459213 0.298305
ENSG00000185745 IFIT1 READ Del 1.039481 0.082019 0.433750 0.309091
ENSG00000185745 IFIT1 COAD Del 5.596625 0.084740 0.388510 0.226164
ENSG00000185745 IFIT1 SARC Del 0.701212 0.120060 0.563043 0.525292
ENSG00000185745 IFIT1 GBM Del 4.346515 0.087438 0.704747 0.887348
ENSG00000185745 IFIT1 ESCA Del 1.570423 0.121210 0.382624 0.353261
ENSG00000185745 IFIT1 THCA Del 1.956122 0.014971 0.507180 0.022044
ENSG00000185745 IFIT1 HNSC Del 2.831976 0.075910 0.353616 0.256705
ENSG00000185745 IFIT1 LIHC Del 1.003036 0.070811 0.500274 0.256757
ENSG00000185745 IFIT1 DLBC Del 2.449370 0.227808 0.785172 0.145833
ENSG00000185745 IFIT1 BLCA Del 4.316672 0.126575 0.417175 0.406863
ENSG00000185745 IFIT1 BRCA Del 7.985261 0.106661 0.394124 0.295370
ENSG00000185745 IFIT1 STAD Del 4.618793 0.105074 0.390151 0.247166
ENSG00000185745 IFIT1 PRAD Del 21.964064 0.213229 0.522690 0.245935
ENSG00000185745 IFIT1 UCEC Del 6.042765 0.095812 0.559508 0.137291
ENSG00000185745 IFIT1 MESO Del 0.665323 0.121954 0.467682 0.310345
ENSG00000185745 IFIT1 OV Del 10.403037 0.303666 0.562006 0.392055