Ensembl ID ENSG00000185651 Gene ID 7332 Accession 12488
Gene Symbol UBE2L3 Alias E2-F1;L-UBC;UBCH7;UbcM4 Full Name ubiquitin conjugating enzyme E2 L3
Position 22 : 21549447 - 21624034 Length 74588 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

ENSG00000185651 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000185651 0.58 3.82e-15 KICH
ENSG00000185651 0.59 9.46e-13 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000185651 prostate cancer 22140652
ENSG00000185651 esophageal cancer 22382060
ENSG00000185651 metastatic prostate cancers 22586312
ENSG00000185651 tumor 29137415
ENSG00000185651 Cancer 29969176
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000185651 STAD 0.047 low
ENSG00000185651 CHOL 0.038 high
ENSG00000185651 UVM 0.031 high
ENSG00000185651 PAAD 0.038 high
ENSG00000185651 UCEC 0.0052 low
ENSG00000185651 LGG 0.0034 high
ENSG00000185651 LUSC 0.026 low
ENSG00000185651 HNSC 0.0095 high
ENSG00000185651 READ 0.005 low
ENSG00000185651 KIRP 0.044 low
ENSG00000185651 KICH 0.016 high
ENSG00000185651 LUAD 0.023 high
ENSG00000185651 THYM 0.0014 low
ENSG00000185651 BRCA 0.035 high
ENSG00000185651 PRAD 0.0091 low
ENSG00000185651 TGCT 0.047 low
ENSG00000185651 BLCA 0.0021 low
ENSG00000185651 LAML 0.00014 high
ENSG00000185651 GBM 0.0037 low
ENSG00000185651 SKCM 0.01 high
ENSG00000185651 CESC 0.02 low
ENSG00000185651 LIHC 0.00014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency