Ensembl ID ENSG00000185627 Gene ID 5719 Accession 9558
Gene Symbol PSMD13 Alias S11;Rpn9;p40.5;HSPC027 Full Name proteasome 26S subunit, non-ATPase 13
Position 11 : 236966 - 252984 Length 16019 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

ENSG00000185627 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000185627 PSMD13 0.39 3.30e-14 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000185627 PSMD13 cancers 28165654
ENSG00000185627 PSMD13 cancer 29064820
ENSG00000185627 PSMD13 tumours 31619667
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000185627 PSMD13 MESO 0.00038 high
ENSG00000185627 PSMD13 UVM 0.0097 high
ENSG00000185627 PSMD13 PAAD 0.022 high
ENSG00000185627 PSMD13 UCEC 0.0017 low
ENSG00000185627 PSMD13 ACC 0.00021 high
ENSG00000185627 PSMD13 LUSC 0.029 high
ENSG00000185627 PSMD13 HNSC 0.011 high
ENSG00000185627 PSMD13 READ 0.041 high
ENSG00000185627 PSMD13 KIRP 0.0083 high
ENSG00000185627 PSMD13 KICH 0.015 high
ENSG00000185627 PSMD13 LUAD 0.009 high
ENSG00000185627 PSMD13 PCPG 0.0057 low
ENSG00000185627 PSMD13 BRCA 0.013 low
ENSG00000185627 PSMD13 GBM 0.016 high
ENSG00000185627 PSMD13 SKCM 0.034 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency