Ensembl ID ENSG00000185238 Gene ID 10196 Accession 30163
Gene Symbol PRMT3 Alias HRMT1L3 Full Name protein arginine methyltransferase 3
Position 11 : 20387558 - 20509338 Length 121781 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ENSG00000185238 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000185238 PRMT3 0.41 2.34e-13 BRCA
ENSG00000185238 PRMT3 1.26 2.59e-40 COAD
ENSG00000185238 PRMT3 0.80 3.12e-14 KICH
ENSG00000185238 PRMT3 1.41 2.46e-51 LUSC
ENSG00000185238 PRMT3 0.76 1.12e-18 LIHC
ENSG00000185238 PRMT3 0.88 7.44e-30 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000185238 PRMT3 tumor 15334060
ENSG00000185238 PRMT3 tumor 19095693
ENSG00000185238 PRMT3 cancer 23445220
ENSG00000185238 PRMT3 cancer 25406853
ENSG00000185238 PRMT3 tumor 28338320
ENSG00000185238 PRMT3 tumor 29442054
ENSG00000185238 PRMT3 tumor 30577570
ENSG00000185238 PRMT3 tumor 31324208
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000185238 PRMT3 MESO 0.0078 high
ENSG00000185238 PRMT3 SARC 0.016 high
ENSG00000185238 PRMT3 THCA 0.011 high
ENSG00000185238 PRMT3 READ 0.01 low
ENSG00000185238 PRMT3 KIRP 0.026 high
ENSG00000185238 PRMT3 KICH 0.019 high
ENSG00000185238 PRMT3 PCPG 0.017 low
ENSG00000185238 PRMT3 BRCA 0.019 high
ENSG00000185238 PRMT3 COAD 0.038 low
ENSG00000185238 PRMT3 UCS 0.0077 high
ENSG00000185238 PRMT3 PRAD 0.021 high
ENSG00000185238 PRMT3 BLCA 0.029 low
ENSG00000185238 PRMT3 GBM 0.023 low
ENSG00000185238 PRMT3 SKCM 0.0028 low
ENSG00000185238 PRMT3 CESC 0.042 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000185238 PRMT3 OV Del 2.570459 0.212416 0.559443 0.450777